Background
Methods
Setting
Participants
Inclusion and exclusion criteria
Ethical approval
Instruments
Statistical analyses
Results
Sample characteristics
Variables | Total | Male | Female | Sex difference | P value |
---|---|---|---|---|---|
No. (%) | No. (%) | No. (%) | OR (95% CI) | ||
Sex | |||||
Male | 186 (48.3) | - | - | - | - |
Female | 199 (51.7) | - | - | ||
Religion | |||||
All others | 90 (23.4) | 50 (13.0) | 40 (10.4) | Ref. | |
Hindu | 295 (76.6) | 136 (35.3) | 159 (41.3) | 1.46 (0.91,2.35) | 0.12 |
Ethnicity | |||||
High caste | 173 (45.0) | 83 (21.60) | 90 (23.4) | Ref. | |
Newar | 65 (16.9) | 27 (7.0) | 38 (9.9) | 1.29 (0.73,2.31) | 0.38 |
Hilly indigenous (Janajati) | 90 (23.4) | 54 (14.0) | 36 (9.4) | 0.62 (0.37,1.03) | 0.07 |
Occupational castes (Dalit) | 11 (2.9) | 8 (2.1) | 3 (0.8) | 0.35 (0.09,1.35) | 0.13 |
All others | 46 (11.9) | 14 (3.6) | 32 (8.3) | 2.11 (1.05,4.23) | 0.04 |
Marital status | |||||
Married | 264 (68.6) | 138 (35.8) | 126 (32.7) | Ref. | |
Others | 121 (31.4) | 48 (12.5) | 73 (19.0) | 1.66 (1.07,2.57) | 0.02 |
Residence | |||||
Rural | 60 (15.6) | 22 (5.7) | 38 (9.9) | Ref. | |
Urban | 242 (62.9) | 108 (28.1) | 134 (34.8) | 0.72 (0.40,1.29) | 0.27 |
Sub-urban | 82 (21.3) | 56 (14.5) | 26 (6.8) | 0.27 (0.13,0.54) | <0.001 |
Occupation* | |||||
Unemployed | 8 (2.1) | 2 (0.5) | 6 (1.56) | Ref. | |
House wife | 125 (32.5) | 60 (15.6) | 65 (16.9) | 0.36 (0.07,1.86) | 0.22 |
Farmer | 59 (15.3) | 28 (7.3) | 31 (8.1) | 0.37 (0.07,1.98) | 0.25 |
Service | 32 (8.3) | 15 (3.9) | 17 (4.4) | 0.38 (0.07,2.16) | 0.27 |
Retired | 86 (22.3) | 46 (11.9) | 40 (10.4) | 0.29 (0.01,1.52) | 0.14 |
Laborers | 14 (3.6) | 8 (2.1) | 6 (1.6) | 0.25 (0.04,1.70) | 0.16 |
Business | 44 (11.4) | 20 (5.2) | 24 (6.2) | 0.40 (0.07,2.20) | 0.29 |
All others | 14 (3.6) | 7 (1.9) | 7 (1.8) | 0.33 (0.05,2.26) | 0.26 |
Education | |||||
No formal | 182 (47.3) | 85 (22.07) | 97 (25.20) | Ref. | |
Below primary | 38 (9.9) | 15 (3.9) | 23 (6.0) | 1.34 (0.66,2.74) | 0.42 |
Primary/secondary | 57 (14.8) | 27 (7.0) | 30 (7.8) | 0.974 (0.54,1.77) | 0.93 |
School leaving certificate | 108 (28.1) | 59 (15.3) | 49 (12.7) | 0.73 (0.45,1.18) | 0.19 |
Family type | |||||
Nuclear | 305 (79.2) | 148 (38.4) | 157 (40.8) | Ref. | |
Joint | 80 (20.8) | 38 (9.9) | 42 (10.9) | 1.04 (0.64,1.71) | 0.87 |
Continuous variables | Range | Mean ± SD | Sex difference (T-test value) | 95% Confidence interval |
pvalue | ||
---|---|---|---|---|---|---|---|
Total | Male | Female | |||||
Age (years) | 23-100 | 52.0 ± 13.1 | 52.2 ± 12.6 | 51.7 ± 13.5 | 0.40 | -2.10, 3.15 | 0.69 |
Education (years) | 0-19 | 5.8 ± 6.7 | 6.3 ± 6.9 | 5.4 ± 6.5 | 1.29 | -0.46, 2.22 | 0.20 |
No of members in family | 1-20 | 5.0 ± 3.0 | 5.1 ± 3.1 | 4.8 ± 2.8 | 1.21 | -0.23, 0.96 | 0.23 |
Monthly income (thousand rupees) | 0-200 | 17.9 ± 37.0 | 18.7 ± 39.9 | 17.2 ±34.2 | 0.40 | -59.20, 89.39 | 0.69 |
Monthly family income (thousand rupees) | 0-500 | 50.7 ± 68.2 | 43.9 ±5.6 | 57.0 ± 77.3 | -1.89 | -26.73, 51.69 | 0.06 |
Monthly family expenditure (thousand rupees) | 0-130 | 28.7 ± 25.9 | 26.7 ± 24.1 | 30.6 ± 27.3 | -1.51 | -91.47, 12.09 | 0.13 |
Monthly diabetes related health care cost (thousand rupees) | 0-35 | 2.2 ± 4.3 | 2.1 ± 4.2 | 2.3 ± 4.5 | -0.48 | -1.08, 0.66 | 0.63 |
Depression
Characteristics | Total samples | |||
---|---|---|---|---|
Variables | Categories | Mean (SD) | Beta (95% CI) | P Value |
Sex | Male | 18.6 ± 7.6 | Ref. | <0.01 |
Female | 20.9 ± 8.1 | 2.2 (0.6, 3.8) | ||
Religion | All others | 21.3 ± 8.7 | Ref. | 0.03 |
Hindu | 19.3 ± 7.7 | -2.1 (-4.0,-0.2) | ||
Ethnicity | High caste | 19.3 ± 7.3 | Ref. | |
Newar | 19.6 ± 8.4 | -0.7 (-3.3,1.9) | 0.62 | |
Hilly indigenous (Janajati) | 20.5 ± 8.6 | -0.4(-3.4,2.6) | 0.80 | |
Occupational castes (Dalit) | 21.1 ± 10.7 | 0.5 (-2.4,3.3) | 0.74 | |
Others | 20.0 ± 7.7 | 1.1 (-4.2,6.4) | 0.68 | |
Marital status | Married | 20.6 ± 8.2 | Ref. | |
All others | 19.41 ± 7.9 | -1.2 (-2.9,0.5) | 0.17 | |
Residence | Rural | 20.2 ± 7.8 | Ref. | |
Urban | 20.3 ± 8.3 | 2.3 (-0.4,4.9) | 0.09 | |
Sub-urban | 17.9 ± 6.7 | 2.4 (0.4,4.5) | 0.02 | |
Occupation | Unemployed | 20.4 ± 17.9 | Ref. | |
House wife | 19.6 ± 8.0 | 2.9 (-4.1,9.8) | 0.42 | |
Farmer | 21.7 ± 6.7 | 2.1 (-2.4,6.5) | 0.36 | |
Service | 19.1 ± 9.1 | 4.2 (-0.5,8.9) | 0.08 | |
Retired | 19.3 ± 7.3 | 1.6 (-3.4,6.6) | 0.53 | |
Student | 20.0 ± 5.7 | 1.8 (-2.8,6.3) | 0.44 | |
Laborers | 18.5 ± 10.0 | 2.5 (-9.4,14.4) | 0.68 | |
Business | 20.2 ± 7.0 | 1.0 (-4.9,6.9) | 0.74 | |
All others | 17.5 ± 6.5 | 2.7 (-2.1,7.6) | 0.27 | |
Education | No formal | 20.7 ± 7.7 | Ref. | |
Formal but below primary | 20.2 ± 7.1 | 2.7 (0.8,4.6) | <0.01 | |
Primary/secondary | 20.2 ± 7.7 | 2.3 (-0.6,5.2) | 0.12 | |
SCL + (class 10 passed) | 17.9 ± 8.6 | 2.2 (-0.3,4.8) | 0.09 | |
Family type | Nuclear | 19.8 ± 7.5 | Ref. | |
Joint | 19.9 ± 9.6 | 0.1 (-1.9,2.1) | 0.91 | |
Parental history of DM | No | 20.7 ± 7.9 | ref | |
Yes | 18.0 ± 7.8 | -2.7 (-4.3,-1.0) | <0.01 | |
Treatment modality | Oral | 19.5 ± 7.7 | Ref. | |
Any insulin | 21.5 ± 8.4 | 2.8 (0.5,5.2) | 0.02 | |
All others | 16.7 ± 6.9 | 4.77 (2.3,7.3) | <0.001 | |
Non adherence | No | 18.2 ± 7.2 | Ref. | |
Yes | 22.6 ± 8.5 | 4.4 (2.8, 6.0) | <0.001 | |
Frequency of non adherence | ≤once a week | 19.8 ± 8.9 | Ref. | |
>one a week | 24.8 ± 7.5 | 5.0 (2.3,7.8) | <0.001 | |
Any diabetic complication | No | 17.9 ± 7.0 | Ref. | |
yes | 21.4 ± 8.4 | 3.6 (2.0,5.2) | <0.001 | |
Erectile dysfunction | No | 19.5 ± 7.9 | Ref. | |
Yes | 28.4 ± 4.8 | 8.9 (4.4,13.4) | <0.001 | |
Smoking | Never | 19.6 ± 7.3 | Ref. | |
Past | 19.0 ± 8.5 | -1.2 (-3.2,0.7) | 0.22 | |
Current | 20.9 ± 8.6 | -1.7 (-4.1,0.3) | 0.10 | |
Alcohol use | Never | 19.6 ± 7.7 | Ref. | |
Past | 20.3 ± 7.5 | -0.1 (-2.1,1.9) | 0.93 | |
Current | 19.7 ± 8.9 | 0.6 (-1.7,2.8) | 0.61 | |
History HTN | No | 18.8 ± 7.68 | Ref. | |
Yes | 20.8 ± 8.15 | 2.0 (0.4,3.6) | 0.01 | |
HTN medication | No | 16.2 ± 5.4 | ref | |
Yes | 20.9 ± 8.1 | 4.7 (1.0,8.5) | 0.01 | |
Family history of HTN | No | 20.6 ± 8.2 | Ref. | |
Yes | 18.3 ± 7.8 | -1.8 (-3.6,-0.1) | 0.03 |
Characteristics | Beta (95% CI) | p-value |
---|---|---|
Age (years) | -0.09 (-0.15, -0.03) | <0.01 |
Education (years) | -0.17 (-0.29, -0.05) | <0.01 |
No of members in family | -0.02 (-0.29, 0.25) | 0.90 |
Monthly income (thousand rupees) | 0.01 (-0.01, 0.03) | 0.33 |
Monthly family income (thousand rupees) | -0.01 (-0.00, 0.01) | 0.85 |
Monthly family expenditure (thousand rupees) | -0.01 (-0.04, 0.02) | 0.54 |
Monthly diabetes related health care cost (thousand rupees) | -0.01 (-0.00,0.01) | 0.87 |
Duration of diagnosis of DM | -0.13 (-0.25,-0.01) | 0.03 |
Duration of diagnosis of HTN | 0.09 (-0.06,0.24) | 0.26 |
Systolic BP | 0.31 (0.27,0.35) | <0.001 |
Diastolic BP | 0.42 (0.37,0.48) | <0.001 |
BMI | -0.01 (-0.21,0.18) | 0.90 |
WHR | 18.5 (7.65,29.44) | <0.001 |
HbA1c | 3.16 (2.82, 3.49) | <0.001 |
Variables | Predictors for total BDI score | |||
---|---|---|---|---|
Beta | (95% CI) | P Value | ||
Intercept | -29.92 | -38.81, -21.03 | <0.001 | |
Sex (female) | 0.67 | -0.34, 1.67 | 0.34 | |
Age (years) | -0.01 | -0.05, 0.03 | 0.72 | |
Religion (Hindu) | -0.81 | -2.21, 0.59 | 0.26 | |
Ethnicity | High Caste Hindu | Ref. | ||
Newar | -0.86 | -2.23, 0.50 | 0.21 | |
Hill indigenous (Janajati) | -1.21 | -2.75, 0.33 | 0.12 | |
Occupational castes (Dalit) | -0.40 | -3.34, 2.54 | 0.79 | |
All others | 0.93 | -0.72, 2.58 | 0.27 | |
Marital status (married) | 0.69 | -0.45, 1.84 | 0.24 | |
Years of education | -0.06 | -0.13, 0.02 | 0.14 | |
Monthly income (thousand rupees) | 0.03 | 0.01, 0.04 | <0.001 | |
Family type (nuclear) | 1.60 | 0.21, 3.00 | 0.03 | |
Total family members | 0.20 | -0.00, 0.38 | 0.05 | |
No known parental history of DM | 1.48 | 0.33, 2.62 | 0.01 | |
Family history of HTN | -0.75 | -1.89, 0.38 | 0.19 | |
History of HTN | -0.31 | -1.34, 0.72 | 0.55 | |
Smoking | Never | Ref. | ||
Past | -1.05 | -2.40, 0.29 | 0.12 | |
Current | 0.08 | -1.32, 1.48 | 0.91 | |
Alcohol use | Never | Ref. | ||
Past | -0.22 | -1.58, 1.14 | 0.75 | |
Current | -0.63 | -2.07, 0.81 | 0.39 | |
Treatment modality for DM | Oral | Ref. | ||
All insulin | 1.74 | 0.60, 2.88 | <0.001 | |
All other | -0.81 | -2.32, 0.68 | 0.29 | |
Non-adherence | 1.05 | 0.02, 2.08 | 0.05 | |
DM complication | 1.19 | 0.18, 2.21 | 0.02 | |
Erectile dysfunction | 4.74 | 1.94, 7.53 | <0.01 | |
BP Systolic (mmHg) | 0.13 | 0.08, 0.17 | <0.001 | |
BP Diastolic (mmHg) | 0.14 | 0.08, 0.20 | <0.001 | |
WHR | 9.12 | 2.47, 15.77 | 0.01 | |
HbA1c (%) | 2.08 | 1.76, 2.41 | <0.001 |