Background
Methods
The Leicester Cough Questionnaire (LCQ)
Patients
Questionnaires
Translation procedure
Validation
Statistical analysis
Results
Patients
n | 152 | |
---|---|---|
Sex m, f (%f) | 50, 102 (67%) | |
Age, years | 59 ± 12 | |
Duration of cough, years | 5.0 | |
FEV1 %predicted | 103 ± 21 | |
LCQ | physical | 4.4 ± 1.1 |
psychological | 4.2 ± 1.0 | |
social | 3.8 ± 1.3 | |
total | 12.3 ± 3.0 | |
HADS | anxiety | 4.6 ± 3.5 |
depression | 4.1 ± 3.8 | |
SF-36 | general health | 57.3 ± 23.2 |
Borg cough scale | 3.6 ± 1.7 | |
Current smoker | 8% | |
Pack-years (min-max) | 15 (1–100) |
Concurrent validity
Validated outcome scales | LCQ physical | LCQ psychological | LCQ social | LCQ total |
---|---|---|---|---|
Borg cough scale | -0.37 | -0.38 | -0.36 | -0.41 |
HADS anxiety | -0.41 | -0.40 | -0.33 | -0.43 |
HADS depression | -0.36 | -0.36 | -0.38 | -0.42 |
HADS total | -0.42 | -0.42 | -0.39 | -0.46 |
SF-36 general health | 0.54 | 0.28 | 0.30 | 0.41 |
SF-36 vitality | 0.61 | 0.38 | 0.45 | 0.55 |
SF-36 mental | 0.39 | 0.41 | 0.39 | 0.45 |
SF-36 pain | 0.46 | 0.22 | 0.28 | 0.36 |
SF-36 emotional | 0.35 | 0.32 | 0.16 (NS) | 0.30 |
SF-36 physical | 0.49 | 0.23 | 0.29 | 0.37 |
SF-36 social functioning | 0.50 | 0.38 | 0.43 | 0.50 |
SF-36 physical functioning | 0.50 | 0.24 | 0.34 | 0.40 |
SF-36 health changes | 0.11 (NS) | 0.22 | 0.22 | 0.22 |
Internal consistency
Test-retest reliability
Domain LCQ | Intraclass correlation coefficient | 95%CI | p-value | |
---|---|---|---|---|
Birring [11] | Zwolle | |||
Physical | 0.93 | 0.86 | 0.76–0.92 | <0.0001 |
Psychological | 0.90 | 0.93 | 0.88–0.96 | |
Social | 0.88 | 0.93 | 0.87–0.96 | |
Total | 0.96 | 0.93 | 0.87–0.96 |
Responsiveness
Domain LCQ | Improvement score | 95%CI |
---|---|---|
Physical | 1.42 | 1.14–1.71 |
Psychological | 1.77 | 1.47–2.06 |
Social | 2.10 | 1.70–2.49 |
Total | 5.28 | 4.41–6.15 |