Erschienen in:
01.09.2011 | Breast Oncology
Multidisciplinary Considerations in the Implementation of the Findings from the American College of Surgeons Oncology Group (ACOSOG) Z0011 Study: A Practice-Changing Trial
verfasst von:
Abigail S. Caudle, MD, Kelly K. Hunt, MD, Henry M. Kuerer, MD, Funda Meric-Bernstam, MD, Anthony Lucci, MD, Isabelle Bedrosian, MD, Gildy V. Babiera, MD, Rosa F. Hwang, MD, Merrick I. Ross, MD, Barry W. Feig, MD, Karen Hoffman, MD, Jennifer K. Litton, MD, Aysegul A. Sahin, MD, Wei Yang, MD, Gabriel N. Hortobagyi, MD, Thomas A. Buchholz, MD, Elizabeth A. Mittendorf, MD
Erschienen in:
Annals of Surgical Oncology
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Ausgabe 9/2011
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Excerpt
Surgical management of breast cancer has evolved from routine use of radical mastectomy to less disfiguring and extensive procedures, including breast-conserving approaches, for appropriately selected patients. Whereas this transition occurred over several decades, until recently axillary lymph node dissection (ALND) remained standard practice for patients with both node-positive and node-negative breast cancer. The introduction of sentinel lymph node dissection (SLND) was a major departure from ALND allowing for an alternative for nodal staging with less morbidity for the increasing population of patients presenting with clinically node-negative disease.
1,
2 Although some early studies suggested a survival advantage for patients who undergo ALND compared with no axillary surgery, the likelihood that removing negative nodes could improve outcomes has been questioned. …
