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Annals of Surgical Oncology
Erschienen in: Annals of Surgical Oncology 8/2007

01.08.2007 | Gynecologic Oncology

Laparoscopic Sentinel Node Biopsy in Cervical Cancer Using a Combined Detection: 5–Years Experience

verfasst von: Charles Coutant, MD, Olivier Morel, MD, Yann Delpech, MD, PhD, Serge Uzan, MD, Emile Daraï, MD, PhD, Emmanuel Barranger, MD

Erschienen in: Annals of Surgical Oncology | Ausgabe 8/2007

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Abstract

Background

To evaluate the feasibility after 5 years experience of a laparoscopic sentinel node (SN) procedure with combined radioisotopic and patent blue labeling in patients with cervical cancer.

Methods

Sixty-seven patients (median age 48.9 years) with cervical cancer underwent a laparoscopic SN procedure using an endoscopic gamma probe, after both radioactive and patent blue injections. After the procedure, all the patients underwent complete laparoscopic pelvic/para-aortic lymphadenectomy.

Results

At least one SN was identified in 57 patients (85.1%). According to the Stage, the SN identification rate was 91.2% in early-stage cervical cancer and 78.5% in locally advanced cervical cancer. The mean number of SN was 2.3 per patient (range 1–5). A total of 129 SNs were removed. Lymph node metastasis involvement was identified in the 20 SNs (15.5%) from 14 patients (24.6%). Nine of the 14 patients had at least one macrometastases, three patients presented micrometastases in H&S, and two patients presented isolated single cells. Six patients presented a pelvic non-SN involvement including two patients whose SNs were uninvolved. The false-negative SNs rate was 12.5% (two patients out of 16). Both patients have locally advanced cervical cancer.

Conclusion

This study confirms that laparoscopic SN detection with a combination of radiocolloid and patent blue is accurate in patients with early cervical cancer to assess pelvic lymph node status.
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Metadaten
Titel
Laparoscopic Sentinel Node Biopsy in Cervical Cancer Using a Combined Detection: 5–Years Experience
verfasst von
Charles Coutant, MD
Olivier Morel, MD
Yann Delpech, MD, PhD
Serge Uzan, MD
Emile Daraï, MD, PhD
Emmanuel Barranger, MD
Publikationsdatum
01.08.2007
Verlag
Springer-Verlag
Erschienen in
Annals of Surgical Oncology / Ausgabe 8/2007
Print ISSN: 1068-9265
Elektronische ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-007-9424-6

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