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Clinical Drug Investigation

Erschienen in:

01.11.2009 | Case Report

Pancytopenia Associated with Levetiracetam Treatment

verfasst von: Dr Massimo Gallerani, Elisa Mari, Benedetta Boari, Rossella Carletti, Anna Marra, Michele Cavallo

Erschienen in: Clinical Drug Investigation | Ausgabe 11/2009

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Abstract

Levetiracetam is a pyrrolidine derivate that is approved for the treatment of seizures. It has a favourable pharmacokinetic profile, no clearly established pharmacological interactions, good tolerability and offers the possibility of rapid treatment.

We describe a case of pancytopenia and multiple infections observed in the context of levetiracetam treatment. A 65-year-old woman who underwent surgical removal of a meningioma developed progressive pancytopenia complicated by pneumonia and multiple liver abscesses after starting levetiracetam therapy. Bone marrow aspiration and biopsy confirmed the diagnosis. A gradual spontaneous recovery of normal haematopoiesis followed discontinuation of levetiracetam.

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Titel: Pancytopenia Associated with Levetiracetam Treatment
verfasst von: Dr Massimo Gallerani
Elisa Mari
Benedetta Boari
Rossella Carletti
Anna Marra
Michele Cavallo
Publikationsdatum: 01.11.2009
Verlag: Springer International Publishing
Erschienen in: Clinical Drug Investigation / Ausgabe 11/2009
Print ISSN: 1173-2563
Elektronische ISSN: 1179-1918
DOI: https://doi.org/10.2165/11319450-000000000-00000

Springer Medizin

Abstract

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