Erschienen in:
01.04.2012 | Case Report
Littoral Cell Angioma and Angiosarcoma of the Spleen: Report of Two Cases in Siblings and Review of the Literature
verfasst von:
Michael Kranzfelder, Margit Bauer, Thomas Richter, Martina Rudelius, Martin Huth, Peter Wagner, Helmut Friess, Josef Stadler
Erschienen in:
Journal of Gastrointestinal Surgery
|
Ausgabe 4/2012
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Excerpt
Littoral cell angioma (LCA), a primary benign tumour of the spleen, was first described by Falk et al. in 1991.
1 Arising from the normal littoral cells lining the sinus channels of the splenic red pulp due to yet unknown stimuli,
2 LCA presents with intermediate features between those of endothelial and histiocytic cells. The most frequent clinical sign is splenomegaly. A malignant transformation to littoral cell angiosarcoma is very rare;
3‐
5 however, an association with other malignancies has been reported recently.
6 …