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01.12.2012 | Research | Ausgabe 1/2012 Open Access

Malaria Journal 1/2012

Malaria rapid diagnostic test transport and storage conditions in Burkina Faso, Senegal, Ethiopia and the Philippines

Zeitschrift:
Malaria Journal > Ausgabe 1/2012
Autoren:
Audrey Albertini, Evan Lee, Sheick Oumar Coulibaly, Markos Sleshi, Babacar Faye, Mary Lorraine Mationg, Kadi Ouedraogo, Abeba G Tsadik, Sendeaw Maksha Feleke, Ibrahima Diallo, Oumar Gaye, Jennifer Luchavez, Jessica Bennett, David Bell
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1475-2875-11-406) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare they have no competing interests.

Authors’ contributions

AA, DB and EL designed the study protocol and instructions. MM, KO, ID, OG, AG and SM carried out the monitoring and data collection process. AA and EL carried out the analysis. AA, SOC, BF, MS, JB, DB and EL drafted the manuscript. All authors have read and approved the manuscript.

Abstract

Background

As more point of care diagnostics become available, the need to transport and store perishable medical commodities to remote locations increases. As with other diagnostics, malaria rapid diagnostic tests (RDTs) must be highly reliable at point of use, but exposure to adverse environmental conditions during distribution has the potential to degrade tests and accuracy. In remote locations, poor quality diagnostics and drugs may have significant negative health impact that is not readily detectable by routine monitoring. This study assessed temperature and humidity throughout supply chains used to transport and store health commodities, such as RDTs.

Methods

Monitoring devices capable of recording temperature and humidity were deployed to Burkina Faso (8), Senegal (10), Ethiopia (13) and the Philippines (6) over a 13-month period. The devices travelled through government supply chains, usually alongside RDTs, to health facilities where RDTs are stored, distributed and used. The recording period spanned just over a year, in order to avoid any biases related to seasonal temperature variations.

Results

In the four countries, storage and transport temperatures regularly exceeded 30.0°C; maximum humidity level recorded was above 94% for the four countries. In three of the four countries, temperatures recorded at central storage facilities exceeded pharmaceutical storage standards for over 20% of the time, in another case for a majority of the time; and sometimes exceeded storage temperatures at peripheral sites.

Conclusions

Malaria RDTs were regularly exposed to temperatures above recommended limits for many commercially-available RDTs and other medical commodities such as drugs, but rarely exceeded the recommended storage limits for particular products in use in these countries. The results underline the need to select RDTs, and other commodities, according to expected field conditions, actively manage the environmental conditions in supply chains in tropical and sub-tropical climates. This would benefit from a re-visit of current global standards on stability of medical commodities based in tropical and sub-tropical climatic zones.
Zusatzmaterial
Authors’ original file for figure 1
12936_2012_2603_MOESM1_ESM.pdf
Authors’ original file for figure 2
12936_2012_2603_MOESM2_ESM.pdf
Authors’ original file for figure 3
12936_2012_2603_MOESM3_ESM.pdf
Literatur
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