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2015 | OriginalPaper | Buchkapitel

10. Markerallergene und Panallergene bei Baum- und Gräserpollenallergie

verfasst von : DDr. med. Katharina Gangl, Univ.-Prof. Dr. Verena Niederberger, Univ.-Prof. Dr. med. Rudolf Valenta, Dr. rer. nat. Andreas Nandy

Erschienen in: Molekulare Allergiediagnostik

Verlag: Springer Berlin Heidelberg

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Zusammenfassung

Die molekulare Allergiediagnostik (komponentenaufgelöste Diagnostik, „component resolved diagnostic“, CRD) erlaubt bei Verdacht auf Gräser- und Baumpollenallergie die Identifikation der verantwortlichen Allergenquelle durch den Nachweis von spezifischem IgE. Insbesondere kann mit geeigneten Markerallergenen eine echte Sensibilisierung gegen Baum- oder Gräserpollen von der Kreuzreaktivität durch Pollenpanallergene (Profilin und Polcalcine) unterschieden und die fehlende analytische Spezifität von Allergenextrakten überwunden werden. Vor allem bei scheinbar polysensibilisierten Patienten mit zahlreichen Reaktionen auf Pollenextrakte ermöglicht die CRD somit eine allergenspezifische Diagnose unabhängig von den Panallergenen sowie eine fundierte Entscheidung für oder gegen eine spezifische Immuntherapie und ihre Zusammensetzung. Im folgenden Kapitel werden jene Allergene näher beschrieben, die eine eindeutige Sensibilisierung widerspiegeln und daher als Markerallergene für Baum- und Gräserpollenallergie gelten:

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Titel: Markerallergene und Panallergene bei Baum- und Gräserpollenallergie
verfasst von: DDr. med. Katharina Gangl
Univ.-Prof. Dr. Verena Niederberger
Univ.-Prof. Dr. med. Rudolf Valenta
Dr. rer. nat. Andreas Nandy
Verlag: Springer Berlin Heidelberg
Buch: Molekulare Allergiediagnostik
Print ISBN: 978-3-662-45220-2

Electronic ISBN: 978-3-662-45221-9

Copyright-Jahr: 2015
DOI: https://doi.org/10.1007/978-3-662-45221-9_10

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10. Markerallergene und Panallergene bei Baum- und Gräserpollenallergie

Zusammenfassung

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Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

HNO-Op. auch mit über 90?

Intrakapsuläre Tonsillektomie gewinnt an Boden

Bilateraler Hörsturz hat eine schlechte Prognose

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Zusammenfassung

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Neu im Fachgebiet HNO

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

HNO-Op. auch mit über 90?

Intrakapsuläre Tonsillektomie gewinnt an Boden

Bilateraler Hörsturz hat eine schlechte Prognose

Update HNO