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01.12.2023 | Research

Meaning and Purpose (MaP) therapy in advanced cancer patients: a randomised controlled trial

verfasst von: David W. Kissane, Irene Bobevski, Jane Appleton, Genevieve Murphy, Anna Laverty-Wilson, Pauley Kessel, Natasha Michael, Richard Chye, Carrie Lethborg

Erschienen in: Supportive Care in Cancer | Ausgabe 12/2023

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Abstract

Purpose

We aimed to examine the efficacy of Meaning and Purpose (MaP) Therapy in promoting posttraumatic growth and meaningful life attitudes (choices and goal seeking) in people living with advanced cancer.

Methods

Patients with a prognosis ≥ 1 year were stratified across two sites and randomised to receive MaP therapy and regular oncology/palliative care (Intervention) or usual care (Control). They completed measures at baseline (t0), post-intervention (12 weeks, t1) and 12 weeks later (t2). Our primary outcome was posttraumatic growth (PTGI); secondary outcome measures included life attitudes (LAPR), spiritual wellbeing (FACIT-Sp), anxiety, demoralization and depression. Trial Registration Number: ACTRN12618001751268, 7 January 2019.

Results

We consented 107 from 404 eligible patients (26.5%) and randomised 55 to MaP Invention (35 completing t1, 25 t2) and 52 to Control (32 completing t1, 25 t2). Fidelity of the intervention was sustained. PTGI mean scores were significantly higher post-intervention on analysis by covariance (Cohen’s d = 0.7 at t1 & d = 0.5 at t2). Secondary measures were significant, including LAPR (d = 0.4) and FACIT-Sp (meaning subscale d = 0.4; total d = 0.4). Participants completing six sessions achieved more noteworthy effect sizes.

Conclusion

This brief, structured individual intervention shows promise for sustaining sense of coherence, meaning and choices in life despite living with advanced cancer.

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Titel: Meaning and Purpose (MaP) therapy in advanced cancer patients: a randomised controlled trial
verfasst von: David W. Kissane
Irene Bobevski
Jane Appleton
Genevieve Murphy
Anna Laverty-Wilson
Pauley Kessel
Natasha Michael
Richard Chye
Carrie Lethborg
Publikationsdatum: 01.12.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Supportive Care in Cancer / Ausgabe 12/2023
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-023-08189-1

Springer Medizin

Meaning and Purpose (MaP) therapy in advanced cancer patients: a randomised controlled trial