Medical Oncology

ERCC6L is a biomarker and therapeutic target for non–small cell lung adenocarcinoma

Guoxin Hou, Zhimin Lu, Yanyu Bi, Jingjing Deng, Xinmei Yang

Blue light induces ROS mediated apoptosis and degradation of AML1-ETO oncoprotein in Kasumi-1 cells

Jianjian Zhuang, Liping Xia, Zheyu Zou, Juxin Yin

In silico bioinformatics analysis for identification of differentially expressed genes and therapeutic drug molecules in Glucocorticoid-resistant Multiple myeloma

Somnath Ghosal, Subrata Banerjee

Effects of metformin on human bone-derived mesenchymal stromal cell—breast cancer cell line interactions

Maryana Teufelsbauer, Clemens Lang, Adelina Plangger, Barbara Rath, Doris Moser, Clement Staud, Christine Radtke, Christoph Neumayer, Gerhard Hamilton

Tetrahydrobiopterin induces proteasome inhibitor resistance and tumor progression in multiple myeloma

Hua Zhang, Jintong Chen, Mingyue Zhang, Munan Zhao, Luyao Zhang, Bin Liu, Siqing Wang

In silico identification of the specific pathways in each stage of colorectal cancer and the association of their top genes with drug resistance and sensitivity

Reza Hashemi, Maryam Peymani, Kamran Ghaedi, Hana Saffar

Knockout of high-mobility group box 1 in B16F10 melanoma cells induced host immunity-mediated suppression of in vivo tumor growth

Kanako Yokomizo, Kayoko Waki, Miyako Ozawa, Keiko Yamamoto, Sachiko Ogasawara, Hirohisa Yano, Akira Yamada

Oncotype DX testing does not affect clinical practice in stage IIa colon cancer

Benjamin G. Allar, Evangelos Messaris, Vitaliy Y. Poylin, Benjamin L. Schlechter, Thomas E. Cataldo

Ambient air emissions of endocrine-disrupting metals and the incidence of hormone receptor- and HER2-dependent female breast cancer in USA

Esther Ro, Vivian Vu, Yudan Wei

In-vitro analysis on the potential use of dental pulp mesenchymal stem cells on arecoline-induced oral epithelial cells

Archana A. Gupta, Supriya Kheur, Saranya Varadarajan, Chandini Rajkumar, Vikrant R. Patil

DNA methylation marker to estimate ovarian cancer cell fraction

Takahiro Ebata, Satoshi Yamashita, Hideyuki Takeshima, Hiroshi Yoshida, Yoshiko Kawata, Nao Kino, Toshiharu Yasugi, Yasuhisa Terao, Kan Yonemori, Tomoyasu Kato, Toshikazu Ushijima

Evidence of a role for interleukin-6 in anoikis resistance in oral squamous cell carcinoma

Management of oligoprogression in non-small cell lung cancer patients

Alfredo Tartarone, Rosa Lerose, Marina Tartarone

Inhibition of DDX3 and COX-2 by forskolin and evaluation of anti-proliferative, pro-apoptotic effects on cervical cancer cells: molecular modelling and in vitro approaches

Innovation in cancer therapeutics and regulatory perspectives

Pinky Sharma, Vikas Jhawat, Pooja Mathur, Rohit Dutt

The role of miR-153 and related upstream/downstream pathways in cancers: from a potential biomarker to treatment of tumor resistance and a therapeutic target

Glioblastoma recurrent cells switch between ATM and ATR pathway as an alternative strategy to survive radiation stress

Ekjot Kaur, Madhura Ketkar, Shilpee Dutt

Interim analysis of companion, prospective, phase II, clinical trials assessing the efficacy and safety of multi-modal total eradication therapy in men with synchronous oligometastatic prostate cancer

How to ensure uninterrupted treatment of radiotherapy patients during delta variants of SARS-CoV-2 virus epidemic: the latest experience from Xi’an, China

Yongkai Lu, Ruijuan Chen, Yi Li

ERBB2 S310F mutation independently activates PI3K/AKT and MAPK pathways through homodimers to contribute gallbladder carcinoma growth

Forward to a methodological proposal to support cancer patients: the dialogics’ contribution for the precision care

Eleonora Pinto, Rita Alfieri, Luisa Orrù, Marta Silvia Dalla Riva, Gian Piero Turchi

Mutation in SF3B1 gene promotes formation of polyploid giant cells in Leukemia cells

Correction to: The role of the WNT signaling pathway in the maxillary sinus squamous cell carcinoma

Bakiye Goker Bagca, Cigir Biray Avci, Baha Sezgin, Ali Veral, Sercan Gode, Halil Bulent Karci

Effects of an enteral nutrient-rich therapy with omega-3 fatty acids in patients with unresectable or recurrent biliary tract cancer or pancreatic cancer during chemotherapy: a case–control study

Controversy of tissue-agnostic approvals in immunotherapy and targeted therapy

KRT15 promotes colorectal cancer cell migration and invasion through β-catenin/MMP-7 signaling pathway

20(s)-ginsenoside Rh2 promotes TRAIL-induced apoptosis by upregulating DR5 in human hepatocellular carcinoma cells

A bioinformatic analysis of WFDC2 (HE4) expression in high grade serous ovarian cancer reveals tumor-specific changes in metabolic and extracellular matrix gene expression

The functions, oncogenic roles, and clinical significance of circular RNAs in renal cell carcinoma

Heme-regulated inhibitor: an overlooked eIF2α kinase in cancer investigations

PIM1/STAT3 axis: a potential co-targeted therapeutic approach in triple-negative breast cancer

ENO3 promotes colorectal cancer progression by enhancing cell glycolysis

Optimized flow cytometric detection of transient receptor potential vanilloid-1 (TRPV1) in human hematological malignancies

Photodynamic therapy using mannose-conjugated chlorin e6 increases cell surface calreticulin in cancer cells and promotes macrophage phagocytosis

Tumor-associated macrophages of the M1/M2 phenotype are involved in the regulation of malignant biological behavior of breast cancer cells through the EMT pathway

The role of histone deacetylase 3 in breast cancer

Unique combinations of epigenetic modifiers synergistically impair the viability of the U87 glioblastoma cell line while exhibiting minor or moderate effects on normal stem cell growth

Chidamide augment sorafenib-derived anti-tumor activities in human osteosarcoma cells lines and xenograft mouse model

Expression of proliferation-related genes in BM-MSC-treated ALL cells in hypoxia condition is regulated under the influence of epigenetic factors in-vitro

Cell line models for drug discovery in PIK3CA-mutated colorectal cancers

The Role of NRF2/KEAP1 Pathway in Glioblastoma: Pharmacological Implications

TMCO1 expression promotes cell proliferation and induces epithelial–mesenchymal transformation in human gliomas

Novel immune subtypes identification of HER2-positive breast cancer based on immunogenomic landscape

Engineering tumor-derived small extra cellular vesicles to encapsulate miR-34a, effectively inhibits 4T1 cell proliferation, migration, and gene expression

Long non-coding RNA AC245100.4 contributes to prostate cancer migration via regulating PAR2 and activating p38-MAPK pathway

Alterations in cellular metabolisms after Imatinib therapy: a review

Olaparib for Chinese metastatic castration-resistant prostate cancer: A real-world study of efficacy and gene predictive analysis

Hippo pathway-related genes expression is deregulated in myeloproliferative neoplasms

The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells

In vitro antiproliferative and cytotoxic activities of novel triphenyltin isoselenocyanate in human breast carcinoma cell lines MCF 7 and MDA-MB-231

Therapeutic natural compounds Enzastaurin and Palbociclib inhibit MASTL kinase activity preventing breast cancer cell proliferation

Synergistic antitumor effect of Andrographolide and cisplatin through ROS-mediated ER stress and STAT3 inhibition in colon cancer

A phase 1b multicenter study of TAS-102 in combination with irinotecan in patients with advanced recurrent or unresectable gastric and gastroesophageal adenocarcinoma after at least one line of treatment with a fluoropyrimidine and platinum-containing regimen

Stereotactic body radiotherapy for spinal metastases: a review