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Erschienen in: HNO 12/2018

30.10.2018 | Tumormarker | Leitthema

Therapie der rezidivierten und fernmetastasierten Plattenepithelkarzinome des Kopf-Hals-Bereichs

Highlights des ASCO-Meetings 2018

verfasst von: L. Bußmann, A. Münscher, PD Dr. C.-J. Busch

Erschienen in: HNO | Ausgabe 12/2018

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Zusammenfassung

In diesem Jahr wurde die Therapie von Patienten mit rezidivierten und metastasierten Plattenepithelkarzinomen des Kopf-Hals-Bereichs (R/M-HNSCC) vorrangig von der Immuntherapie dominiert. Die entsprechenden Arbeiten werden in einem gesonderten Artikel präsentiert. Darüber hinaus wurden auf dem ASCO-Kongress insbesondere Ergebnisse von Phase-II-Studien präsentiert, in denen wie auch in den letzten Jahren der Einsatz neuerer Medikamente (monoklonale Antikörper, „small molecules“) eine große Rolle spielt. Des Weiteren wurde ein klinisches Scoringsystem zur Evaluation der Prognose bei R/M-HNSCC vorgestellt und der Einfluss des HPV-Status auf das Überleben in dieser Patientenkohorte untersucht. Die nun hier vorgestellten Studien geben die verschiedenen Konzepte der medikamentösen Behandlung von R/M-HNSCC wieder und repräsentieren die Vielfalt der Therapieansätze in der Rezidiv- und Metastasensituation.
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Metadaten
Titel
Therapie der rezidivierten und fernmetastasierten Plattenepithelkarzinome des Kopf-Hals-Bereichs
Highlights des ASCO-Meetings 2018
verfasst von
L. Bußmann
A. Münscher
PD Dr. C.-J. Busch
Publikationsdatum
30.10.2018
Verlag
Springer Medizin
Erschienen in
HNO / Ausgabe 12/2018
Print ISSN: 0017-6192
Elektronische ISSN: 1433-0458
DOI
https://doi.org/10.1007/s00106-018-0580-8

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