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Erschienen in: Forensic Science, Medicine and Pathology 4/2016

04.06.2016 | Original Article

Methods for determining time of death

verfasst von: Burkhard Madea

Erschienen in: Forensic Science, Medicine and Pathology | Ausgabe 4/2016

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Abstract

Medicolegal death time estimation must estimate the time since death reliably. Reliability can only be provided empirically by statistical analysis of errors in field studies. Determining the time since death requires the calculation of measurable data along a time-dependent curve back to the starting point. Various methods are used to estimate the time since death. The current gold standard for death time estimation is a previously established nomogram method based on the two-exponential model of body cooling. Great experimental and practical achievements have been realized using this nomogram method. To reduce the margin of error of the nomogram method, a compound method was developed based on electrical and mechanical excitability of skeletal muscle, pharmacological excitability of the iris, rigor mortis, and postmortem lividity. Further increasing the accuracy of death time estimation involves the development of conditional probability distributions for death time estimation based on the compound method. Although many studies have evaluated chemical methods of death time estimation, such methods play a marginal role in daily forensic practice. However, increased precision of death time estimation has recently been achieved by considering various influencing factors (i.e., preexisting diseases, duration of terminal episode, and ambient temperature). Putrefactive changes may be used for death time estimation in water-immersed bodies. Furthermore, recently developed technologies, such as H magnetic resonance spectroscopy, can be used to quantitatively study decompositional changes. This review addresses the gold standard method of death time estimation in forensic practice and promising technological and scientific developments in the field.
Literatur
1.
Zurück zum Zitat Henssge C, Madea B. Methoden zur Bestimmung der Todeszeit an Leichen. Lübeck: Schmidt-Römhild-Verlag; 1988. Henssge C, Madea B. Methoden zur Bestimmung der Todeszeit an Leichen. Lübeck: Schmidt-Römhild-Verlag; 1988.
2.
Zurück zum Zitat Henssge C, Madea B. Estimation of the time since death in the early post-mortem period. Forensic Sci Int. 2004;144:167–75.PubMedCrossRef Henssge C, Madea B. Estimation of the time since death in the early post-mortem period. Forensic Sci Int. 2004;144:167–75.PubMedCrossRef
3.
4.
5.
Zurück zum Zitat Madea B, Henssge C. Timing of death. In: Payne-James J, Busuttil A, editors. Forensic Medicine: clinical and pathological aspects. London: Greenwich Medical Media Limited; 2003. p. 91–114. Madea B, Henssge C. Timing of death. In: Payne-James J, Busuttil A, editors. Forensic Medicine: clinical and pathological aspects. London: Greenwich Medical Media Limited; 2003. p. 91–114.
6.
Zurück zum Zitat Madea B. Rechtsmedizin: Befunderhebung, Rekonstruktion, Begutachtung. 3rd ed. Berlin: Springer; 2015. Madea B. Rechtsmedizin: Befunderhebung, Rekonstruktion, Begutachtung. 3rd ed. Berlin: Springer; 2015.
7.
Zurück zum Zitat Albrecht A, Gerling I, Henssge C. Zur Anwendung des Rektaltemperatur-Todeszeit-Nomogramms am Leichenfundort. Z Rechtsmed. 1990;103:257–78.PubMedCrossRef Albrecht A, Gerling I, Henssge C. Zur Anwendung des Rektaltemperatur-Todeszeit-Nomogramms am Leichenfundort. Z Rechtsmed. 1990;103:257–78.PubMedCrossRef
8.
Zurück zum Zitat Althaus L, Henssge C. Rectal temperature time of death nomogram: sudden change of ambient temperature. Forensic Sci Int. 1999;99:171–8.PubMedCrossRef Althaus L, Henssge C. Rectal temperature time of death nomogram: sudden change of ambient temperature. Forensic Sci Int. 1999;99:171–8.PubMedCrossRef
9.
Zurück zum Zitat Brown A, Marshall TK. Body temperature as a means of estimating the time of death. Forensic Sci. 1974;4:125–33.PubMedCrossRef Brown A, Marshall TK. Body temperature as a means of estimating the time of death. Forensic Sci. 1974;4:125–33.PubMedCrossRef
10.
Zurück zum Zitat De Saram GSW, Webster G, Kathirgamatamby N. Post-mortem temperature and the time of death. J Crim Law Criminol. 1955;46:562–77.CrossRef De Saram GSW, Webster G, Kathirgamatamby N. Post-mortem temperature and the time of death. J Crim Law Criminol. 1955;46:562–77.CrossRef
11.
Zurück zum Zitat Henssge C. Rectal temperature time of death nomogram: dependence of corrective factors on the body weight under stronger thermic insulation conditions. Forensic Sci Int. 1992;54:51–6.PubMedCrossRef Henssge C. Rectal temperature time of death nomogram: dependence of corrective factors on the body weight under stronger thermic insulation conditions. Forensic Sci Int. 1992;54:51–6.PubMedCrossRef
12.
Zurück zum Zitat Henssge C. Precision of estimating the time of death by mathematical expression of rectal body cooling. Z Rechtsmed. 1979;83:49–67.PubMedCrossRef Henssge C. Precision of estimating the time of death by mathematical expression of rectal body cooling. Z Rechtsmed. 1979;83:49–67.PubMedCrossRef
13.
Zurück zum Zitat Henssge C. Death time estimation in case work I. The rectal temperature time of death nomogram. Forensic Sci Int. 1988;38:209–36.PubMedCrossRef Henssge C. Death time estimation in case work I. The rectal temperature time of death nomogram. Forensic Sci Int. 1988;38:209–36.PubMedCrossRef
14.
Zurück zum Zitat Henssge C. Temperature based methods II. In: Henssge C, Knight B, Krompecher T, Madea B, Nokes L, editors. The estimation of the time since death in the early post-mortem period. 2nd ed. London: Edward Arnold; 2002. Henssge C. Temperature based methods II. In: Henssge C, Knight B, Krompecher T, Madea B, Nokes L, editors. The estimation of the time since death in the early post-mortem period. 2nd ed. London: Edward Arnold; 2002.
15.
Zurück zum Zitat Henssge C, Beckmann ER, Wischhusen F, Brinkmann B. A Determination of time of death by measuring central brain temperature. Z Rechtsmed. 1984;93:1–22.PubMed Henssge C, Beckmann ER, Wischhusen F, Brinkmann B. A Determination of time of death by measuring central brain temperature. Z Rechtsmed. 1984;93:1–22.PubMed
16.
Zurück zum Zitat Henssge C, Frekers R, Reinhardt S, Beckmann ER. Determination of time of death on the basis of simultaneous measurement of brain and rectal temperature. Z Rechtsmed. 1984;93:123–33.PubMed Henssge C, Frekers R, Reinhardt S, Beckmann ER. Determination of time of death on the basis of simultaneous measurement of brain and rectal temperature. Z Rechtsmed. 1984;93:123–33.PubMed
17.
Zurück zum Zitat Henssge C, Hahn S, Madea B. Praktische Erfahrungen mit einem Abkühlungsdummy. Beitr Gerichtl Med XLIV. 1986;123–126. Henssge C, Hahn S, Madea B. Praktische Erfahrungen mit einem Abkühlungsdummy. Beitr Gerichtl Med XLIV. 1986;123–126.
18.
Zurück zum Zitat Henssge C, Madea B, Schaar U, Pitzken C. Die Abkühlung eines Dummy unter verschiedenen Bedingungen im Vergleich zur Leichenabkühlung. Beitr Gerichtl Med XLV. 1987;145–149. Henssge C, Madea B, Schaar U, Pitzken C. Die Abkühlung eines Dummy unter verschiedenen Bedingungen im Vergleich zur Leichenabkühlung. Beitr Gerichtl Med XLV. 1987;145–149.
19.
Zurück zum Zitat Henssge C, Madea B, Gallenkemper E. Death time estimation in case work II. Integration of different methods. Forensic Sci Int. 1988;39:77–87.PubMedCrossRef Henssge C, Madea B, Gallenkemper E. Death time estimation in case work II. Integration of different methods. Forensic Sci Int. 1988;39:77–87.PubMedCrossRef
20.
Zurück zum Zitat Henssge C, Althaus L, Bolt J, Freislederer A, Haffner HT, Henssge CA, et al. Experiences with a compound method for estimating the time since death. I. Rectal temperature nomogram for time since death. II. Integration of non-temperature-based methods. Int J Legal Med. 2000;6:303–31.CrossRef Henssge C, Althaus L, Bolt J, Freislederer A, Haffner HT, Henssge CA, et al. Experiences with a compound method for estimating the time since death. I. Rectal temperature nomogram for time since death. II. Integration of non-temperature-based methods. Int J Legal Med. 2000;6:303–31.CrossRef
21.
Zurück zum Zitat Henssge C, Madea B. Frühe Leichenerscheinungen und Todeszeitbestimmung im frühpostmortalen Intervall. In: Brinkmann B, Madea B, editors. Handbuch Rechtsmedizin, vol. I. Berlin: Springer; 2004. Henssge C, Madea B. Frühe Leichenerscheinungen und Todeszeitbestimmung im frühpostmortalen Intervall. In: Brinkmann B, Madea B, editors. Handbuch Rechtsmedizin, vol. I. Berlin: Springer; 2004.
22.
Zurück zum Zitat Henssge C. Basics and application of the ‘nomogram method’ at the scene. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: Taylor & Francis Group/CRC Press; 2015. p. 63–114. Henssge C. Basics and application of the ‘nomogram method’ at the scene. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: Taylor & Francis Group/CRC Press; 2015. p. 63–114.
23.
Zurück zum Zitat Henssge C, Madea B. Practical casework. Integration of different methods in casework. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 227–37. Henssge C, Madea B. Practical casework. Integration of different methods in casework. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 227–37.
24.
Zurück zum Zitat Hubig M, Muggenthaler H, Mall G. Finite element method in temperature-based death time determination. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 114–33. Hubig M, Muggenthaler H, Mall G. Finite element method in temperature-based death time determination. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 114–33.
25.
Zurück zum Zitat Hubig M, Muggenthaler H, Sinicina I, Mall G. Temperature based forensic death time estimation: The standard model in experimental test. Legal Medicine. Tokyo; 2015. Hubig M, Muggenthaler H, Sinicina I, Mall G. Temperature based forensic death time estimation: The standard model in experimental test. Legal Medicine. Tokyo; 2015.
26.
Zurück zum Zitat Marshall TK, Hoare FE. I Estimating the time of death. The rectal cooling after death and its mathematical expression. II The use of the cooling formula in the study of postmortem body cooling. III The use of the body temperature in estimating the time of death. J Forensic Sci. 1962;7:56–81, 189–210, 211–221. Marshall TK, Hoare FE. I Estimating the time of death. The rectal cooling after death and its mathematical expression. II The use of the cooling formula in the study of postmortem body cooling. III The use of the body temperature in estimating the time of death. J Forensic Sci. 1962;7:56–81, 189–210, 211–221.
27.
Zurück zum Zitat Hunnius PV, Mallach HJ, Mittmeyer HJ. Quantitative pressure measurements of livores mortis relative to the determination of the time of death. Z Rechtsmed. 1973;73:325–44.CrossRef Hunnius PV, Mallach HJ, Mittmeyer HJ. Quantitative pressure measurements of livores mortis relative to the determination of the time of death. Z Rechtsmed. 1973;73:325–44.CrossRef
28.
Zurück zum Zitat Madea B, Knight B. Postmortem lividity. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 59–62. Madea B, Knight B. Postmortem lividity. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 59–62.
29.
Zurück zum Zitat Mallach HJ. Zur Frage der Todeszeitbestimmung. Berl Med. 1964;18:577–82. Mallach HJ. Zur Frage der Todeszeitbestimmung. Berl Med. 1964;18:577–82.
30.
31.
Zurück zum Zitat Rosendahl W, Döppes D. Radiocarbon dating. Basic principles and applications. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 259–67. Rosendahl W, Döppes D. Radiocarbon dating. Basic principles and applications. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 259–67.
34.
Zurück zum Zitat Beier G, Liebhardt E, Schuck M, Spann M. Measurement of rigor mortis on human skeletal muscles in situ. Z Rechtsmed. 1977;79:277–83.PubMedCrossRef Beier G, Liebhardt E, Schuck M, Spann M. Measurement of rigor mortis on human skeletal muscles in situ. Z Rechtsmed. 1977;79:277–83.PubMedCrossRef
35.
Zurück zum Zitat Krompecher T, Bergerioux C. Experimental evaluation of rigor mortis. VII. Effect of ante- and postmortem electrocution on the evolution of rigor mortis. Forensic Sci Int. 1988;38:27–35.PubMedCrossRef Krompecher T, Bergerioux C. Experimental evaluation of rigor mortis. VII. Effect of ante- and postmortem electrocution on the evolution of rigor mortis. Forensic Sci Int. 1988;38:27–35.PubMedCrossRef
36.
Zurück zum Zitat Krompecher T, Fryc O. Experimentelle Untersuchungen an der Leichenstarre unter Einfluss von körperlicher Anstrengung. Beitr Gerichtl Med. 1978;36:345–9.PubMed Krompecher T, Fryc O. Experimentelle Untersuchungen an der Leichenstarre unter Einfluss von körperlicher Anstrengung. Beitr Gerichtl Med. 1978;36:345–9.PubMed
37.
Zurück zum Zitat Krompecher T, Fryc O. Experimental evaluation of rigor mortis. III. Comparative study of the evolution of rigor mortis in different sized muscle groups in rats. Forensic Sci Int. 1978;12:97–102.PubMedCrossRef Krompecher T, Fryc O. Experimental evaluation of rigor mortis. III. Comparative study of the evolution of rigor mortis in different sized muscle groups in rats. Forensic Sci Int. 1978;12:97–102.PubMedCrossRef
38.
Zurück zum Zitat Krompecher T, Fryc O. Experimental evaluation of rigor mortis. IV. Change in strength and evolution of rigor mortis in the case of physical exercise preceding death. Forensic Sci Int. 1978;12:103–7.PubMedCrossRef Krompecher T, Fryc O. Experimental evaluation of rigor mortis. IV. Change in strength and evolution of rigor mortis in the case of physical exercise preceding death. Forensic Sci Int. 1978;12:103–7.PubMedCrossRef
39.
Zurück zum Zitat Krompecher T, Fryc O. Zur Frage der Todeszeitbestimmung auf Grund der Leichenstarre. Beitr Gerichtl Med. 1979;37:285–9.PubMed Krompecher T, Fryc O. Zur Frage der Todeszeitbestimmung auf Grund der Leichenstarre. Beitr Gerichtl Med. 1979;37:285–9.PubMed
40.
Zurück zum Zitat Krompecher T, Fryc O. Experimental evaluation of rigor mortis. V. Effects of temperature on the evolution of rigor mortis. Forensic Sci Int. 1981;17:19–26.PubMedCrossRef Krompecher T, Fryc O. Experimental evaluation of rigor mortis. V. Effects of temperature on the evolution of rigor mortis. Forensic Sci Int. 1981;17:19–26.PubMedCrossRef
41.
Zurück zum Zitat Krompecher T. Rigor mortis: estimation of the time since death by the evaluation of the cadaveric rigidity. In: Henssge C, Knight B, Krompecher T, Madea B, Nokes L, editors. The estimation of the time since death in the early postmortem period. 2nd ed. London: Edward Arnold; 2002. p. 144–60. Krompecher T. Rigor mortis: estimation of the time since death by the evaluation of the cadaveric rigidity. In: Henssge C, Knight B, Krompecher T, Madea B, Nokes L, editors. The estimation of the time since death in the early postmortem period. 2nd ed. London: Edward Arnold; 2002. p. 144–60.
42.
Zurück zum Zitat Krompecher T. Rigor Mortis. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 41–57. Krompecher T. Rigor Mortis. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 41–57.
43.
Zurück zum Zitat Madea B, Krompecher T, Knight B. Muscles and tissue changes after death. In: Henssge C, Knight B, Krompecher T, Madea B, Nokes L, editors. The estimation of the time since death in the early postmortem period. 2nd ed. London: Edward Arnold; 2002. Madea B, Krompecher T, Knight B. Muscles and tissue changes after death. In: Henssge C, Knight B, Krompecher T, Madea B, Nokes L, editors. The estimation of the time since death in the early postmortem period. 2nd ed. London: Edward Arnold; 2002.
44.
Zurück zum Zitat Dotzauer G. Idiomuskulärer Wulst und postmortale Blutung. Dtsch Z Gerichtl Med. 1958;46:761–71. Dotzauer G. Idiomuskulärer Wulst und postmortale Blutung. Dtsch Z Gerichtl Med. 1958;46:761–71.
45.
Zurück zum Zitat Madea B. Längsschnittuntersuchungen zur supravitalen elektrischen Erregbarkeit der Skelettmuskulatur. I. Objektivierung der supravitalen Muskelkontraktion. Rechtsmed. 1990;2:107–21. Madea B. Längsschnittuntersuchungen zur supravitalen elektrischen Erregbarkeit der Skelettmuskulatur. I. Objektivierung der supravitalen Muskelkontraktion. Rechtsmed. 1990;2:107–21.
46.
Zurück zum Zitat Madea B. Längsschnittuntersuchungen zur supravitalen elektrischen Erregbarkeit der Skelettmuskulatur. II. Quantifizierung der supravitalen Muskelkontraktion. Rechtsmed. 1990;3:44–50. Madea B. Längsschnittuntersuchungen zur supravitalen elektrischen Erregbarkeit der Skelettmuskulatur. II. Quantifizierung der supravitalen Muskelkontraktion. Rechtsmed. 1990;3:44–50.
47.
Zurück zum Zitat Madea B. Estimating time of death from measurement of electrical excitability of skeletal muscle. J Forensic Sci Soc. 1992;32:117–29.PubMedCrossRef Madea B. Estimating time of death from measurement of electrical excitability of skeletal muscle. J Forensic Sci Soc. 1992;32:117–29.PubMedCrossRef
48.
Zurück zum Zitat Madea B, Henssge C. Electrical excitability of skeletal muscle postmortem in casework. Forensic Sci Int. 1990;47:207–27.PubMedCrossRef Madea B, Henssge C. Electrical excitability of skeletal muscle postmortem in casework. Forensic Sci Int. 1990;47:207–27.PubMedCrossRef
49.
Zurück zum Zitat Madea B, Rödig A. Precision of estimating the time since death using different criteria of excitability. For Sci Med Pathol. 2006;2:127–33.CrossRef Madea B, Rödig A. Precision of estimating the time since death using different criteria of excitability. For Sci Med Pathol. 2006;2:127–33.CrossRef
50.
Zurück zum Zitat Madea B. Supravitality in tissues. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 17–40. Madea B. Supravitality in tissues. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 17–40.
51.
Zurück zum Zitat Berg S. Todeszeitbestimmung in der spätpostmortalen Phase. In: Brinkmann B, Madea B, editors. Handbuch Gerichtliche Medizin, vol. 1. Berlin: Springer; 2004. p. 191–204. Berg S. Todeszeitbestimmung in der spätpostmortalen Phase. In: Brinkmann B, Madea B, editors. Handbuch Gerichtliche Medizin, vol. 1. Berlin: Springer; 2004. p. 191–204.
52.
Zurück zum Zitat Bonte W. Der postmortale Proteinkatabolismus. Experimentelle Untersuchungen zum Problem der forensischen Leichenzeitbestimmung. Habilitationsschrift, Göttingen: Medizinische Fakultät der Georg-August-Universität Göttingen; 1978. Bonte W. Der postmortale Proteinkatabolismus. Experimentelle Untersuchungen zum Problem der forensischen Leichenzeitbestimmung. Habilitationsschrift, Göttingen: Medizinische Fakultät der Georg-August-Universität Göttingen; 1978.
53.
Zurück zum Zitat Madea B. Is there recent progress in the estimation of the postmortem interval by means of thanatochemistry? Forensic Sci Int. 2005;151:139–49.PubMedCrossRef Madea B. Is there recent progress in the estimation of the postmortem interval by means of thanatochemistry? Forensic Sci Int. 2005;151:139–49.PubMedCrossRef
54.
Zurück zum Zitat Madea B, Preuss J, Musshoff F. From flourishing life to dust—the natural cycle of growth and decay. In: Wieczorek A, Rosendahl W, editors. Mummies of the world. Munich: Prestel; 2010. p. 14–29. Madea B, Preuss J, Musshoff F. From flourishing life to dust—the natural cycle of growth and decay. In: Wieczorek A, Rosendahl W, editors. Mummies of the world. Munich: Prestel; 2010. p. 14–29.
55.
Zurück zum Zitat Madea B, Kernbach-Wighton G. Autolysis (self-digestion). In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2001. p. 153–61. Madea B, Kernbach-Wighton G. Autolysis (self-digestion). In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2001. p. 153–61.
56.
Zurück zum Zitat Rutty G, Morgan B. Cross-sectional imaging and the postmortem interval. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 269–75. Rutty G, Morgan B. Cross-sectional imaging and the postmortem interval. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 269–75.
57.
Zurück zum Zitat Adelson L, Sunshine I, Rushforth NB, Mankoff M. Vitreous potassium concentration as an indicator of the postmortem interval. J Forensic Sci. 1963;8:503–14.PubMed Adelson L, Sunshine I, Rushforth NB, Mankoff M. Vitreous potassium concentration as an indicator of the postmortem interval. J Forensic Sci. 1963;8:503–14.PubMed
58.
Zurück zum Zitat Adjudantis G, Coutselinis A. Estimation of the time of death by potassioum levels in the vitreous humour. Forensic Sci. 1972;1:55–60.CrossRef Adjudantis G, Coutselinis A. Estimation of the time of death by potassioum levels in the vitreous humour. Forensic Sci. 1972;1:55–60.CrossRef
59.
Zurück zum Zitat Bortolotti F, Pascali JP, Davis GG, Smith FP, Brissie RM, Tagliaro F. Study of vitreous potassium correlation with time since death in the postmortem range from 2 to 110 hours using capillary ion analysis. Med Sci Law. 2011;51(Suppl 1):S20–3.PubMedCrossRef Bortolotti F, Pascali JP, Davis GG, Smith FP, Brissie RM, Tagliaro F. Study of vitreous potassium correlation with time since death in the postmortem range from 2 to 110 hours using capillary ion analysis. Med Sci Law. 2011;51(Suppl 1):S20–3.PubMedCrossRef
60.
Zurück zum Zitat Coe JI. Vitreous potassium as a measure of the postmortem interval: an historical review and critical evaluation. Forensic Sci Int. 1989;42:201–13.PubMedCrossRef Coe JI. Vitreous potassium as a measure of the postmortem interval: an historical review and critical evaluation. Forensic Sci Int. 1989;42:201–13.PubMedCrossRef
61.
Zurück zum Zitat Coe JI. Postmortem chemistry update. Emphasis on forensic application. Am J Forensic Med Pathol. 1993;14:91–117.PubMedCrossRef Coe JI. Postmortem chemistry update. Emphasis on forensic application. Am J Forensic Med Pathol. 1993;14:91–117.PubMedCrossRef
62.
Zurück zum Zitat Hansson L, Uotila U, Lindfors R, Laiho K. Potassium content of the vitreous body as an aid in determining the time of death. J Forensic Sci. 1966;11:390–4.PubMed Hansson L, Uotila U, Lindfors R, Laiho K. Potassium content of the vitreous body as an aid in determining the time of death. J Forensic Sci. 1966;11:390–4.PubMed
63.
Zurück zum Zitat James RA, Hoadley PA, Sampson BG. Determination of postmortem interval by sampling vitreous humour. Am J Forensic Med Pathol. 1997;18:158–62.PubMedCrossRef James RA, Hoadley PA, Sampson BG. Determination of postmortem interval by sampling vitreous humour. Am J Forensic Med Pathol. 1997;18:158–62.PubMedCrossRef
64.
Zurück zum Zitat Jashnani KD, Kale SA, Rupani AB. Vitreous humor: biochemical constituents in estimation of postmortem interval. J Forensic Sci. 2010;55:1523–7.PubMedCrossRef Jashnani KD, Kale SA, Rupani AB. Vitreous humor: biochemical constituents in estimation of postmortem interval. J Forensic Sci. 2010;55:1523–7.PubMedCrossRef
65.
Zurück zum Zitat Klein A, Klein S. Todeszeitbestimmung am menschlichen Auge. MD Thesis, Dresden University; 1978. Klein A, Klein S. Todeszeitbestimmung am menschlichen Auge. MD Thesis, Dresden University; 1978.
66.
Zurück zum Zitat Lange N, Swearer S, Sturner WQ. Human postmortem interval estimation from vitreous potassium: an analysis of original data from six different studies. Forensic Sci Int. 1994;66:159–74.PubMedCrossRef Lange N, Swearer S, Sturner WQ. Human postmortem interval estimation from vitreous potassium: an analysis of original data from six different studies. Forensic Sci Int. 1994;66:159–74.PubMedCrossRef
67.
Zurück zum Zitat Madea B, Henssge C, Hönig W, Gerbracht A. References for determining the time of death by potassium in the vitreous humour. Forensic Sci Int. 1989;8:231–43.CrossRef Madea B, Henssge C, Hönig W, Gerbracht A. References for determining the time of death by potassium in the vitreous humour. Forensic Sci Int. 1989;8:231–43.CrossRef
68.
Zurück zum Zitat Madea B, Herrmann N, Henssge C. Precision of estimating the time since death by vitreous potassium—comparison of two different equations. Forensic Sci Int. 1990;46:277–84.PubMedCrossRef Madea B, Herrmann N, Henssge C. Precision of estimating the time since death by vitreous potassium—comparison of two different equations. Forensic Sci Int. 1990;46:277–84.PubMedCrossRef
69.
Zurück zum Zitat Madea B, Käferstein H, Herrmann N, Sticht G. Hypoxanthine in vitreous humour and cerebrospinal fluid—a marker of postmortem interval and prolonged (vital) hypoxia? Remarks also on hypoxanthine in SIDS. Forensic Sci Int. 1994;65:19–31.PubMedCrossRef Madea B, Käferstein H, Herrmann N, Sticht G. Hypoxanthine in vitreous humour and cerebrospinal fluid—a marker of postmortem interval and prolonged (vital) hypoxia? Remarks also on hypoxanthine in SIDS. Forensic Sci Int. 1994;65:19–31.PubMedCrossRef
70.
Zurück zum Zitat Madea B, Kreuser C, Banaschak S. Postmortem biochemical examination of synovial fluid—a preliminary study. Forensic Sci Int. 2001;118:29–35.PubMedCrossRef Madea B, Kreuser C, Banaschak S. Postmortem biochemical examination of synovial fluid—a preliminary study. Forensic Sci Int. 2001;118:29–35.PubMedCrossRef
71.
Zurück zum Zitat Madea B, Henssge C. Eye changes after death. In: Henssge C, Knight B, Krompecher T, Madea B, Nokes L, editors. The estimation of the time since death in the early postmortem period. 2nd ed. London: Edward Arnold; 2002. Madea B, Henssge C. Eye changes after death. In: Henssge C, Knight B, Krompecher T, Madea B, Nokes L, editors. The estimation of the time since death in the early postmortem period. 2nd ed. London: Edward Arnold; 2002.
72.
Zurück zum Zitat Madea B, Rödig A. Time of death dependent criteria in vitreous humor—precision of estimating the time since death. Forensic Sci Int. 2006;164:87–92.PubMedCrossRef Madea B, Rödig A. Time of death dependent criteria in vitreous humor—precision of estimating the time since death. Forensic Sci Int. 2006;164:87–92.PubMedCrossRef
73.
Zurück zum Zitat Madea B, Henssge C. Eye changes after death. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 161–85. Madea B, Henssge C. Eye changes after death. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 161–85.
74.
Zurück zum Zitat Madea B, Henssge C. Cerebrospinal fluid chemistry. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 186–9. Madea B, Henssge C. Cerebrospinal fluid chemistry. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 186–9.
75.
Zurück zum Zitat Mathur A, Agrawal YK. An overview of methods used for estimation of time since death. Aust J Forensic Sci. 2011;43:275–85.CrossRef Mathur A, Agrawal YK. An overview of methods used for estimation of time since death. Aust J Forensic Sci. 2011;43:275–85.CrossRef
76.
Zurück zum Zitat Mihailovic Z, Atanasijevic T, Popovic V, Milosevic MB, Sperhake JP. Estimation of the postmortem interval by analyzing potassium in the vitreous humor: could repetitive sampling enhance accuracy? Am J Forensic Med Pathol. 2012;33:400–3.PubMedCrossRef Mihailovic Z, Atanasijevic T, Popovic V, Milosevic MB, Sperhake JP. Estimation of the postmortem interval by analyzing potassium in the vitreous humor: could repetitive sampling enhance accuracy? Am J Forensic Med Pathol. 2012;33:400–3.PubMedCrossRef
77.
Zurück zum Zitat Munoz JI, Suarez-Penaranda JM, Otero XL, Rodriguez-Calvo MS, Costas E, Miguens X, et al. A new perspecitive in the estimation of postmortem interval (PMI) based on vitreous. J Forensic Sci. 2001;45:209–2014. Munoz JI, Suarez-Penaranda JM, Otero XL, Rodriguez-Calvo MS, Costas E, Miguens X, et al. A new perspecitive in the estimation of postmortem interval (PMI) based on vitreous. J Forensic Sci. 2001;45:209–2014.
78.
Zurück zum Zitat Munoz Barus JI, Suarez-Penaranda J, Otero XL, Rodriguez-Calvo MS, Costas E, Miguens X, et al. Improved estimation of postmortem interval based on differential behavior of vitreous potassium and hypoxanthine in death by hanging. For Sci Int. 2002;125:67–74. Munoz Barus JI, Suarez-Penaranda J, Otero XL, Rodriguez-Calvo MS, Costas E, Miguens X, et al. Improved estimation of postmortem interval based on differential behavior of vitreous potassium and hypoxanthine in death by hanging. For Sci Int. 2002;125:67–74.
79.
Zurück zum Zitat Pounder J. Postmortem interval. In: Siegel JA, Saukko PJ, Knupfer GC, editors. Encyclopaedia of forensic sciences, vol. 3. San Diego: Academic Press; 2000. p. 1167–72.CrossRef Pounder J. Postmortem interval. In: Siegel JA, Saukko PJ, Knupfer GC, editors. Encyclopaedia of forensic sciences, vol. 3. San Diego: Academic Press; 2000. p. 1167–72.CrossRef
80.
Zurück zum Zitat Rognum TO, Hauge S, Oyasaeter S, Saugstad OD. A new biochemical method for estimation of postmortem time. For Sci Int. 1991;51:139–46. Rognum TO, Hauge S, Oyasaeter S, Saugstad OD. A new biochemical method for estimation of postmortem time. For Sci Int. 1991;51:139–46.
81.
Zurück zum Zitat Siddamsetty AK, Verma SK, Kohli A, Puri D, Singh A. Estimation of time since death form electrolyte, glucose and calcium analysis of postmortem vitreous humour in semi-arid climate. Med Sci Law. 2014;54:158–66.PubMedCrossRef Siddamsetty AK, Verma SK, Kohli A, Puri D, Singh A. Estimation of time since death form electrolyte, glucose and calcium analysis of postmortem vitreous humour in semi-arid climate. Med Sci Law. 2014;54:158–66.PubMedCrossRef
82.
Zurück zum Zitat Stephens RJ, Richards RG. Vitreous humor chemistry: the use of potassium concentration for the prediction of the postmortem interval. J Forensic Sci. 1987;32:503–9.PubMedCrossRef Stephens RJ, Richards RG. Vitreous humor chemistry: the use of potassium concentration for the prediction of the postmortem interval. J Forensic Sci. 1987;32:503–9.PubMedCrossRef
83.
84.
Zurück zum Zitat Sturner WQ, Gantner GE. The postmortem interval. A study of potassium in the vitreous humor. Am J Clin Pathol. 1964;42:137–44.PubMedCrossRef Sturner WQ, Gantner GE. The postmortem interval. A study of potassium in the vitreous humor. Am J Clin Pathol. 1964;42:137–44.PubMedCrossRef
85.
Zurück zum Zitat Tumrana NK, Ambadea VN, Dongreb AP. Thanatochemistry: study of vitreous humor potassium. Alexandria J Med. 2014;50:365–8.CrossRef Tumrana NK, Ambadea VN, Dongreb AP. Thanatochemistry: study of vitreous humor potassium. Alexandria J Med. 2014;50:365–8.CrossRef
86.
Zurück zum Zitat Zhou B, Zhang L, Zhang G, Zhang X, Jiang X. The determination of potassium concentration in vitreous humor by low pressure ion chromatography and its application in the estimation of postmortem interval. J Chromatogr B Analyt Technol Biomed Life Sci. 2007;852:278–81.PubMedCrossRef Zhou B, Zhang L, Zhang G, Zhang X, Jiang X. The determination of potassium concentration in vitreous humor by low pressure ion chromatography and its application in the estimation of postmortem interval. J Chromatogr B Analyt Technol Biomed Life Sci. 2007;852:278–81.PubMedCrossRef
87.
Zurück zum Zitat Zilg B, Bernard S, Alkass K, Berg S, Druid H. A new model for the estimation of time of death from vitreous potassium levels corrected for age and temperature. For Sci Int. 2015;254:158–66. Zilg B, Bernard S, Alkass K, Berg S, Druid H. A new model for the estimation of time of death from vitreous potassium levels corrected for age and temperature. For Sci Int. 2015;254:158–66.
88.
Zurück zum Zitat Zilg B. Postmortem analyses of virtreous fluid. MD Thesis, Department of Oncology-Pathology. Karolinska Institutet, Stockholm, Sweden; 2015. Zilg B. Postmortem analyses of virtreous fluid. MD Thesis, Department of Oncology-Pathology. Karolinska Institutet, Stockholm, Sweden; 2015.
89.
Zurück zum Zitat Reibe S, Doetinchem PV, Madea B. A new simulation-based model for calculating post-mortem intervals using developmental data for Lucilia sericata (Dipt.: Calliphhoridae). Parasitol Res. 2010;107:9–16.PubMedCrossRef Reibe S, Doetinchem PV, Madea B. A new simulation-based model for calculating post-mortem intervals using developmental data for Lucilia sericata (Dipt.: Calliphhoridae). Parasitol Res. 2010;107:9–16.PubMedCrossRef
90.
Zurück zum Zitat Reibe S, Madea B. How promptly do blowflieds colonise fresh carcasses? A study comparing indoor with outdoor locations. For Sci Int. 2010;195:52–7. Reibe S, Madea B. How promptly do blowflieds colonise fresh carcasses? A study comparing indoor with outdoor locations. For Sci Int. 2010;195:52–7.
91.
Zurück zum Zitat Reibe S, Madea B. Use of Megaselia scalaris (Dipt.: Phoridae) for post-mortem interval estimation indoors. Parasitol Res. 2010;106:637–40.PubMedCrossRef Reibe S, Madea B. Use of Megaselia scalaris (Dipt.: Phoridae) for post-mortem interval estimation indoors. Parasitol Res. 2010;106:637–40.PubMedCrossRef
92.
Zurück zum Zitat Reibe S. Forensic entomolgy. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 249–57. Reibe S. Forensic entomolgy. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 249–57.
93.
Zurück zum Zitat Van den Oever R. A review of the literature as to the present possibilities and limitations in estimating the time of death. Med Sci Law. 1976;16:269–76.PubMed Van den Oever R. A review of the literature as to the present possibilities and limitations in estimating the time of death. Med Sci Law. 1976;16:269–76.PubMed
94.
Zurück zum Zitat Camps FE. Establishment of the time of death—a critical assessment. J Forensic Sci. 1959;4:73–82. Camps FE. Establishment of the time of death—a critical assessment. J Forensic Sci. 1959;4:73–82.
95.
Zurück zum Zitat Horowitz M, Maddern GJ, Chatterton BE, Collins PJ, Harding PE, Sherman DJC. Changes in gastric emptying rates with age. Clin Sci. 1984;67:213–8.PubMedCrossRef Horowitz M, Maddern GJ, Chatterton BE, Collins PJ, Harding PE, Sherman DJC. Changes in gastric emptying rates with age. Clin Sci. 1984;67:213–8.PubMedCrossRef
96.
Zurück zum Zitat Horowitz M, Pounder DJ. Gastric emptying—forensic implications of current concepts. Med Sci Law. 1985;25:201–14.PubMed Horowitz M, Pounder DJ. Gastric emptying—forensic implications of current concepts. Med Sci Law. 1985;25:201–14.PubMed
97.
98.
Zurück zum Zitat Madea B, Oehmichen M, Henssge C. Postmortaler Transport von Mageninhalt. Z Rechtsmed. 1986;97:201–6.PubMed Madea B, Oehmichen M, Henssge C. Postmortaler Transport von Mageninhalt. Z Rechtsmed. 1986;97:201–6.PubMed
99.
Zurück zum Zitat Madea B, Knight B. Gastric contents and time since death. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 213–22. Madea B, Knight B. Gastric contents and time since death. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 213–22.
100.
Zurück zum Zitat Tröger HD, Baur C, Spann KW. Mageninhalt und Todeszeitbestimmung. Lübeck: Schmidt-Römhild; 1987. Tröger HD, Baur C, Spann KW. Mageninhalt und Todeszeitbestimmung. Lübeck: Schmidt-Römhild; 1987.
101.
Zurück zum Zitat Madea B, Henssge C. General remarks on estimating the time since death. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 1–6. Madea B, Henssge C. General remarks on estimating the time since death. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 1–6.
102.
Zurück zum Zitat Knight B, Madea B. Historical review on early work on estimating the time since death. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 7–16. Knight B, Madea B. Historical review on early work on estimating the time since death. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 7–16.
103.
Zurück zum Zitat Madea B. Importance of supravitality in forensic medicine. Forensic Sci Int. 1994;69:221–41.PubMedCrossRef Madea B. Importance of supravitality in forensic medicine. Forensic Sci Int. 1994;69:221–41.PubMedCrossRef
104.
Zurück zum Zitat Rutty G. The use of temperatures recorded from the external auditory canal for the estimation of the postmortem interval. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 134–51. Rutty G. The use of temperatures recorded from the external auditory canal for the estimation of the postmortem interval. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 134–51.
105.
Zurück zum Zitat Biermann FM, Potente S. The deployment of conditional probability distributions for death time estimation. Forensic Sci Int. 2011;210:82–6.PubMedCrossRef Biermann FM, Potente S. The deployment of conditional probability distributions for death time estimation. Forensic Sci Int. 2011;210:82–6.PubMedCrossRef
106.
Zurück zum Zitat Potente S. Practical casework. Conditional probability in death time estimation. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 237–48. Potente S. Practical casework. Conditional probability in death time estimation. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 237–48.
107.
Zurück zum Zitat Musshoff F, Klotzbach H, Block W, Traeber F, Schild H, Madea B. Comparison of post-mortem metabolic changes in sheep brain tissue in isolated heads and whole animals using 1H-MR spectroscopy—preliminary results. Int J Legal Med. 2011;125:741–4.PubMedCrossRef Musshoff F, Klotzbach H, Block W, Traeber F, Schild H, Madea B. Comparison of post-mortem metabolic changes in sheep brain tissue in isolated heads and whole animals using 1H-MR spectroscopy—preliminary results. Int J Legal Med. 2011;125:741–4.PubMedCrossRef
108.
Zurück zum Zitat Musshoff F, Madea B. H3-Magnetic resonance spectroscopy. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 203–12. Musshoff F, Madea B. H3-Magnetic resonance spectroscopy. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 203–12.
109.
Zurück zum Zitat Reh H. Diagnostik des Ertrinkungstodes und Bestimmung der Wasserzeit. Düsseldorf: Triltsch; 1969. Reh H. Diagnostik des Ertrinkungstodes und Bestimmung der Wasserzeit. Düsseldorf: Triltsch; 1969.
110.
Zurück zum Zitat Reh H. Anhaltspunkte für die Bestimmung der Wasserliegezeit. Dtsch Z Ges Gerichtl Med. 1967;59:235–45. Reh H. Anhaltspunkte für die Bestimmung der Wasserliegezeit. Dtsch Z Ges Gerichtl Med. 1967;59:235–45.
111.
Zurück zum Zitat Doberentz E, Madea B. Schätzung der Wasserliegezeit. Retrospektive Untersuchung zur Reliabilität. Rechtsmed. 2010;20:393–9. Doberentz E, Madea B. Schätzung der Wasserliegezeit. Retrospektive Untersuchung zur Reliabilität. Rechtsmed. 2010;20:393–9.
112.
Zurück zum Zitat Doberentz E, Madea B. Estimating the time of immersion of bodies found in water—an evaluation of a common method to estimate the minimum time interval of immersion. Revista Espanola de Medicina Legal. 2010;36:51–61.CrossRef Doberentz E, Madea B. Estimating the time of immersion of bodies found in water—an evaluation of a common method to estimate the minimum time interval of immersion. Revista Espanola de Medicina Legal. 2010;36:51–61.CrossRef
113.
Zurück zum Zitat Doberentz E, Madea B. Estimation of duration of immersion. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 189–202. Doberentz E, Madea B. Estimation of duration of immersion. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 189–202.
114.
Zurück zum Zitat Madea B. Estimation of duration of immersion. Nordisk Rettsmedisin. 2002;8:4–10. Madea B. Estimation of duration of immersion. Nordisk Rettsmedisin. 2002;8:4–10.
115.
Zurück zum Zitat Madea B, Stockhausen S, Doberentz E. Bestimmung der Wasserliegezeit nach Reh – weitere Untersuchungen zur Prüfung der Reliabilität. Arch Kriminol. 2016;237:1–2.PubMed Madea B, Stockhausen S, Doberentz E. Bestimmung der Wasserliegezeit nach Reh – weitere Untersuchungen zur Prüfung der Reliabilität. Arch Kriminol. 2016;237:1–2.PubMed
116.
Zurück zum Zitat Wehner F. Die Eingrenzung der Leichenliegezeit im spätpostmortalen Intervall. Neue Ansätze mittels immunhistochemischer. Verfahren Med Welt. 2009;11–12:402–6. Wehner F. Die Eingrenzung der Leichenliegezeit im spätpostmortalen Intervall. Neue Ansätze mittels immunhistochemischer. Verfahren Med Welt. 2009;11–12:402–6.
117.
Zurück zum Zitat Wehner F, et al. Delimitation of the time of death by immunohistochemical insulin detection in pancreatic ß-cells. Forensic Sci Int. 1999;105:161–9.PubMedCrossRef Wehner F, et al. Delimitation of the time of death by immunohistochemical insulin detection in pancreatic ß-cells. Forensic Sci Int. 1999;105:161–9.PubMedCrossRef
118.
Zurück zum Zitat Wehner F, et al. Delimitation of the time of death by immunohistochemical detection of thyroglobulin. Forensic Sci Int. 2000;110:199–206.PubMedCrossRef Wehner F, et al. Delimitation of the time of death by immunohistochemical detection of thyroglobulin. Forensic Sci Int. 2000;110:199–206.PubMedCrossRef
119.
Zurück zum Zitat Wehner F, Wehner H-D, Subke J. Delimitation of the time of death by immunohistochemical detection of calcitonin. Forensic Sci Int. 2001;122:89–94.PubMedCrossRef Wehner F, Wehner H-D, Subke J. Delimitation of the time of death by immunohistochemical detection of calcitonin. Forensic Sci Int. 2001;122:89–94.PubMedCrossRef
120.
Zurück zum Zitat Wehner F, Wehner H-D, Subke J. Delimitation of the time of death by immunohistochemical detection of glucagon on pancreatic ß-cells. Forensic Sci Int. 2002;124:241–8. Wehner F, Wehner H-D, Subke J. Delimitation of the time of death by immunohistochemical detection of glucagon on pancreatic ß-cells. Forensic Sci Int. 2002;124:241–8.
121.
Zurück zum Zitat Madea B. Immunohistochemical methods as an aid in estimating the time since death. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 223–5. Madea B. Immunohistochemical methods as an aid in estimating the time since death. In: Madea B, editor. Estimation of the time since death. 3rd ed. Boca Raton: CRC Press; 2015. p. 223–5.
122.
Zurück zum Zitat Ondrizola A, Riancho JA, de la Vega R, Agudo G, Garcia-Blanco A, de Cos E, et al. miRNA analysis in vitreous humor to determine the time of death: a proof-of-concept pilot study. Int J Legal Med. 2013;127:573–8.CrossRef Ondrizola A, Riancho JA, de la Vega R, Agudo G, Garcia-Blanco A, de Cos E, et al. miRNA analysis in vitreous humor to determine the time of death: a proof-of-concept pilot study. Int J Legal Med. 2013;127:573–8.CrossRef
123.
Zurück zum Zitat Zubakov D, Kokshoorn M, Kloosterman A, Kayser M. New markers for old stains: stable mRNA markers for blood and saliva identification from up to 16-years-old stains. Int J Legal Med. 2009;123:71–4.PubMedCrossRef Zubakov D, Kokshoorn M, Kloosterman A, Kayser M. New markers for old stains: stable mRNA markers for blood and saliva identification from up to 16-years-old stains. Int J Legal Med. 2009;123:71–4.PubMedCrossRef
124.
Zurück zum Zitat Sampaio-Silva F, Magalhaes T, Carvalho F, Dinis-Oliveira RJ, Silvestre R. Profilingo f RNA degradation for estimation of post mortem interval. PLoS ONE. 2013;8:e56507.PubMedPubMedCentralCrossRef Sampaio-Silva F, Magalhaes T, Carvalho F, Dinis-Oliveira RJ, Silvestre R. Profilingo f RNA degradation for estimation of post mortem interval. PLoS ONE. 2013;8:e56507.PubMedPubMedCentralCrossRef
125.
Zurück zum Zitat Li JZ, Bunney BG, Meng F, Hagenauer MH, Walsh DM, Vawter MP, et al. Circadian patterns of gene expression in the human brain and disruption in major depressive disorder. PNAS. 2013;110:9950–5.PubMedPubMedCentralCrossRef Li JZ, Bunney BG, Meng F, Hagenauer MH, Walsh DM, Vawter MP, et al. Circadian patterns of gene expression in the human brain and disruption in major depressive disorder. PNAS. 2013;110:9950–5.PubMedPubMedCentralCrossRef
126.
Zurück zum Zitat Kimura A, Ishida Y, Hayashi T, Nosaka M, Kondo T. Estimating time of death based on the biological clock. Int J Legal Med. 2011;125:385–91.PubMedCrossRef Kimura A, Ishida Y, Hayashi T, Nosaka M, Kondo T. Estimating time of death based on the biological clock. Int J Legal Med. 2011;125:385–91.PubMedCrossRef
127.
Zurück zum Zitat Naeve W. Gerichtliche Medizin für Polizeibeamte. Heidelberg: Kriminalistik Verlag; 1978. Naeve W. Gerichtliche Medizin für Polizeibeamte. Heidelberg: Kriminalistik Verlag; 1978.
Metadaten
Titel
Methods for determining time of death
verfasst von
Burkhard Madea
Publikationsdatum
04.06.2016
Verlag
Springer US
Erschienen in
Forensic Science, Medicine and Pathology / Ausgabe 4/2016
Print ISSN: 1547-769X
Elektronische ISSN: 1556-2891
DOI
https://doi.org/10.1007/s12024-016-9776-y

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