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Erschienen in: Archives of Virology 10/2019

12.07.2019 | Brief Report

Molecular detection and characterization of genotype 1 bovine leukemia virus from beef cattle in the traditional sector in Zambia

verfasst von: Mundia M. Phiri, Evans Kaimoyo, Katendi Changula, Isaac Silwamba, Herman M. Chambaro, Penjaninge Kapila, Masahiro Kajihara, Martin Simuunza, John Bwalya Muma, Girja S. Pandey, Ayato Takada, Aaron S. Mweene, Simbarashe Chitanga, Edgar Simulundu

Erschienen in: Archives of Virology | Ausgabe 10/2019

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Abstract

Whilst bovine leukemia virus (BLV) causes considerable economic losses to the dairy industry worldwide, information on its molecular epidemiology and economic impact in beef cattle is limited. Here, blood from 880 animals from Zambia’s major cattle-rearing provinces was screened for BLV by nested PCR. Positive pools were sequenced and phylogenetically analyzed. The estimated pooled prevalence was 2.1%. All strains belonged to genotype 1 and formed a distinct phylogenetic cluster. The study suggests circulation of genotype 1 BLV in beef cattle in these regions. This is the first report on molecular detection and characterization of BLV from beef cattle in Africa.
Literatur
1.
Zurück zum Zitat Ooshiro M, Konnai S, Katagiri Y, Afuso M, Arakaki N, Tsuha O, Murata S, Ohashi K (2013) Horizontal transmission of bovine leukemia virus from lymphocytotic cattle, and beneficial effects of insect vector control. Vet Rec 173:527CrossRefPubMed Ooshiro M, Konnai S, Katagiri Y, Afuso M, Arakaki N, Tsuha O, Murata S, Ohashi K (2013) Horizontal transmission of bovine leukemia virus from lymphocytotic cattle, and beneficial effects of insect vector control. Vet Rec 173:527CrossRefPubMed
2.
Zurück zum Zitat Juliarena MA, Barrios NC, Lützelschwab MC, Esteban EN, Gutiérrez SE (2017) Bovine leukemia virus: current perspectives. Virus Adapt Treat 2017:13–26CrossRef Juliarena MA, Barrios NC, Lützelschwab MC, Esteban EN, Gutiérrez SE (2017) Bovine leukemia virus: current perspectives. Virus Adapt Treat 2017:13–26CrossRef
4.
Zurück zum Zitat EFSA Panel on Animal Health and Welfare (AHAW) (2015) Enzootic bovine leukosis. EFSA J 13:4188 EFSA Panel on Animal Health and Welfare (AHAW) (2015) Enzootic bovine leukosis. EFSA J 13:4188
5.
Zurück zum Zitat Bauermann FV, Ridpath JF, Dargatz DA (2017) Bovine leukemia virus seroprevalence among cattle presented for slaughter in the United States. J Vet Diagn Investig 29:704–706CrossRef Bauermann FV, Ridpath JF, Dargatz DA (2017) Bovine leukemia virus seroprevalence among cattle presented for slaughter in the United States. J Vet Diagn Investig 29:704–706CrossRef
6.
Zurück zum Zitat Bartlett PC, Sordillo LM, Byrem TM, Norby B, Grooms DL, Swenson CL, Zalucha J, Erskine EJ (2014) Options for the control of bovine leukemia virus in dairy cattle. J Am Vet Med Assoc 244:914–922CrossRefPubMed Bartlett PC, Sordillo LM, Byrem TM, Norby B, Grooms DL, Swenson CL, Zalucha J, Erskine EJ (2014) Options for the control of bovine leukemia virus in dairy cattle. J Am Vet Med Assoc 244:914–922CrossRefPubMed
7.
Zurück zum Zitat Matsumura K, Inoue E, Osawa Y, Okazaki K (2011) Molecular epidemiology of bovine leukemia virus associated with enzootic bovine leukosis in Japan. Virus Res 155:343–348CrossRefPubMed Matsumura K, Inoue E, Osawa Y, Okazaki K (2011) Molecular epidemiology of bovine leukemia virus associated with enzootic bovine leukosis in Japan. Virus Res 155:343–348CrossRefPubMed
8.
Zurück zum Zitat Polat M, Takeshima SN, Hosomichi K, Kim J, Miyasaka T, Yamada K, Arainga M, Murakami T, Matsumoto Y, de la Barra DV, Panei CJ, Gonzalez ET, Kanemaki M, Onuma M, Giovambattista G, Aida Y (2016) A new genotype of bovine leukemia virus in South America identified by NGS-based whole genome sequencing and molecular evolutionary genetic analysis. Retrovirology 13:4CrossRefPubMedPubMedCentral Polat M, Takeshima SN, Hosomichi K, Kim J, Miyasaka T, Yamada K, Arainga M, Murakami T, Matsumoto Y, de la Barra DV, Panei CJ, Gonzalez ET, Kanemaki M, Onuma M, Giovambattista G, Aida Y (2016) A new genotype of bovine leukemia virus in South America identified by NGS-based whole genome sequencing and molecular evolutionary genetic analysis. Retrovirology 13:4CrossRefPubMedPubMedCentral
9.
Zurück zum Zitat Polat M, Moe HH, Shimogiri T, Moe KK, Takeshima S, Aida Y (2017) The molecular epidemiological study of bovine leukemia virus infection in Myanmar cattle. Arch Virol 162:425–437CrossRefPubMed Polat M, Moe HH, Shimogiri T, Moe KK, Takeshima S, Aida Y (2017) The molecular epidemiological study of bovine leukemia virus infection in Myanmar cattle. Arch Virol 162:425–437CrossRefPubMed
10.
Zurück zum Zitat Pandey GS, Simulundu E, Mwiinga D, Samui KL, Mweene AS, Kajihara M, Mangani A, Mwenda R, Ndebe J, Konnai S, Takada A (2017) Clinical and subclinical bovine leukemia virus infection in a dairy cattle herd in Zambia. Arch Virol 162:1051–1056CrossRefPubMed Pandey GS, Simulundu E, Mwiinga D, Samui KL, Mweene AS, Kajihara M, Mangani A, Mwenda R, Ndebe J, Konnai S, Takada A (2017) Clinical and subclinical bovine leukemia virus infection in a dairy cattle herd in Zambia. Arch Virol 162:1051–1056CrossRefPubMed
11.
Zurück zum Zitat Walrand F, Fumoux F, Roelants G, Parodi AL, Levy D (1986) Incidence of bovine leukemia virus specific antibodies in West African cattle. Int J Cancer 37:619–621CrossRefPubMed Walrand F, Fumoux F, Roelants G, Parodi AL, Levy D (1986) Incidence of bovine leukemia virus specific antibodies in West African cattle. Int J Cancer 37:619–621CrossRefPubMed
12.
Zurück zum Zitat Mushi EZ, Wibberley G, Kupe DC (1990) Antibodies to bovine leukemia virus in Botswana. Trop Anim Health Prod 22:126CrossRefPubMed Mushi EZ, Wibberley G, Kupe DC (1990) Antibodies to bovine leukemia virus in Botswana. Trop Anim Health Prod 22:126CrossRefPubMed
13.
Zurück zum Zitat Kaura HT, Hübschle OJ (1994) The occurrence of enzootic bovine leukosis (EBL) in Namibia—an epidemiological study. Deutsche Tierarztliche Wochenschrift 101:66–67PubMed Kaura HT, Hübschle OJ (1994) The occurrence of enzootic bovine leukosis (EBL) in Namibia—an epidemiological study. Deutsche Tierarztliche Wochenschrift 101:66–67PubMed
14.
Zurück zum Zitat Heinonen M, Assefa W (1995) Some observations on bovine leukosis virus antibodies in Ethiopia. Trop Anim Health Prod 27:225–226CrossRefPubMed Heinonen M, Assefa W (1995) Some observations on bovine leukosis virus antibodies in Ethiopia. Trop Anim Health Prod 27:225–226CrossRefPubMed
15.
Zurück zum Zitat Schoepf KC, Kapaga AM, Msami HM, Hyera JM (1997) Serological evidence of the occurrence of enzootic bovine leukosis (EBL) virus infection in cattle in Tanzania. Trop Anim Health Prod 29:15–19CrossRefPubMed Schoepf KC, Kapaga AM, Msami HM, Hyera JM (1997) Serological evidence of the occurrence of enzootic bovine leukosis (EBL) virus infection in cattle in Tanzania. Trop Anim Health Prod 29:15–19CrossRefPubMed
16.
Zurück zum Zitat Meas S, Nakayama M, Usui T, Nakazato Y, Yasuda J, Ohashi K, Onuma M (2004) Evidence for bovine immunodeficiency virus infection in cattle in Zambia. Jpn J Vet Res 52:3–8PubMed Meas S, Nakayama M, Usui T, Nakazato Y, Yasuda J, Ohashi K, Onuma M (2004) Evidence for bovine immunodeficiency virus infection in cattle in Zambia. Jpn J Vet Res 52:3–8PubMed
17.
Zurück zum Zitat Ndou RV, Sejesho F, Dzoma BM, Motsei LE, Nyirenda M, Bakunzi FR (2011) A serosurvey of the prevalence of enzootic bovine leukosis in the Mafikeng area of the North West Province of South Africa. J Hum Ecol 36:53–55CrossRef Ndou RV, Sejesho F, Dzoma BM, Motsei LE, Nyirenda M, Bakunzi FR (2011) A serosurvey of the prevalence of enzootic bovine leukosis in the Mafikeng area of the North West Province of South Africa. J Hum Ecol 36:53–55CrossRef
18.
Zurück zum Zitat Zaghawa A, Beier D, Abd El-Rahim IH, Karim I, El-ballal S, Conraths FJ, Marquardt O (2002) An outbreak of enzootic bovine leukosis in upper Egypt: clinical, laboratory and molecular-epidemiological studies. J Vet Med B Infect Dis Vet Public Health 49:123–129CrossRefPubMed Zaghawa A, Beier D, Abd El-Rahim IH, Karim I, El-ballal S, Conraths FJ, Marquardt O (2002) An outbreak of enzootic bovine leukosis in upper Egypt: clinical, laboratory and molecular-epidemiological studies. J Vet Med B Infect Dis Vet Public Health 49:123–129CrossRefPubMed
19.
Zurück zum Zitat Fechner H, Blankenstein P, Looman AC, Elwert J, Geue L, Albrecht C, Kurg A, Beier D, Marquardt O, Ebner D (1997) Provirus variants of the bovine leukemia virus and their relation to the serological status of naturally infected cattle. Virology 237:261–269CrossRefPubMed Fechner H, Blankenstein P, Looman AC, Elwert J, Geue L, Albrecht C, Kurg A, Beier D, Marquardt O, Ebner D (1997) Provirus variants of the bovine leukemia virus and their relation to the serological status of naturally infected cattle. Virology 237:261–269CrossRefPubMed
20.
Zurück zum Zitat Cowling DW, Gardner IA, Johnson WO (1999) Comparison of methods for estimation of individual-level prevalence based on pooled samples. Prev Vet Med 39:211–225CrossRefPubMed Cowling DW, Gardner IA, Johnson WO (1999) Comparison of methods for estimation of individual-level prevalence based on pooled samples. Prev Vet Med 39:211–225CrossRefPubMed
21.
Zurück zum Zitat Simulundu E, Chambaro HM, Sinkala Y, Kajihara M, Ogawa H, Mori A, Ndebe J, Dautu G, Mataa L, Lubaba CH, Simuntala C, Fandamu P, Simuunza M, Pandey GS, Samui KL, Misinzo G, Takada A, Mweene AS (2018) Co-circulation of multiple genotypes of African swine fever viruses among domestic pigs in Zambia (2013–2015). Transbound Emerg Dis 65:114–122CrossRefPubMed Simulundu E, Chambaro HM, Sinkala Y, Kajihara M, Ogawa H, Mori A, Ndebe J, Dautu G, Mataa L, Lubaba CH, Simuntala C, Fandamu P, Simuunza M, Pandey GS, Samui KL, Misinzo G, Takada A, Mweene AS (2018) Co-circulation of multiple genotypes of African swine fever viruses among domestic pigs in Zambia (2013–2015). Transbound Emerg Dis 65:114–122CrossRefPubMed
22.
Zurück zum Zitat Kimura M (1980) A simple method for estimating evolutionary rate of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 16:111–120CrossRefPubMed Kimura M (1980) A simple method for estimating evolutionary rate of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 16:111–120CrossRefPubMed
23.
Zurück zum Zitat Tamura K, Stecher G, Peterson D, Filipski A, Kumar S (2013) MEGA6: molecular evolutionary genetics analysis (MEGA) software version 6.0. Mol Biol Evol 30:2725–2729CrossRefPubMedPubMedCentral Tamura K, Stecher G, Peterson D, Filipski A, Kumar S (2013) MEGA6: molecular evolutionary genetics analysis (MEGA) software version 6.0. Mol Biol Evol 30:2725–2729CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Hall TA (1999) BioEdit: a user friendly biological sequences alignment editor and analysis program for Window 95/98/NT. Nucleic Acids Symp Ser 41:95–98 Hall TA (1999) BioEdit: a user friendly biological sequences alignment editor and analysis program for Window 95/98/NT. Nucleic Acids Symp Ser 41:95–98
25.
Zurück zum Zitat Murakami H, Uchiyama J, Suzuki C, Nikaido S, Sato RS, Maeda Y, Tomioka M, TakeshimaS Kato H, Sakaguchi M, Sentsui H, Aida Y, Tsukamoto K (2018) Variations in the viral genome and biological properties of bovine leukemia virus wild-type strains. Virus Res 253:103–111CrossRefPubMed Murakami H, Uchiyama J, Suzuki C, Nikaido S, Sato RS, Maeda Y, Tomioka M, TakeshimaS Kato H, Sakaguchi M, Sentsui H, Aida Y, Tsukamoto K (2018) Variations in the viral genome and biological properties of bovine leukemia virus wild-type strains. Virus Res 253:103–111CrossRefPubMed
26.
Zurück zum Zitat Lee E, Kim EJ, Ratthanophart J, Vitoonpong R, Kim BH, Cho IS, Song JY, Lee KK, Shin YK (2016) Molecular epidemiological and serological studies of bovine leukemia virus in cattle in Thailand. Infect Genet Evol 41:245–254CrossRefPubMed Lee E, Kim EJ, Ratthanophart J, Vitoonpong R, Kim BH, Cho IS, Song JY, Lee KK, Shin YK (2016) Molecular epidemiological and serological studies of bovine leukemia virus in cattle in Thailand. Infect Genet Evol 41:245–254CrossRefPubMed
27.
Zurück zum Zitat Mumba C, Häsler B, Muma JB, Munyeme M, Chilolo SD, Skjerve E, Rich MK (2018) Practices of traditional beef farmers in their production and marketing of cattle in Zambia. Trop Anim Health Prod 50:49–62CrossRefPubMed Mumba C, Häsler B, Muma JB, Munyeme M, Chilolo SD, Skjerve E, Rich MK (2018) Practices of traditional beef farmers in their production and marketing of cattle in Zambia. Trop Anim Health Prod 50:49–62CrossRefPubMed
28.
Zurück zum Zitat Moratorio G, Obal G, Dubra A, Correa A, Bianchi S, Buschiazzo A, Cristina J, Pritsch O (2010) Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes. Arch Virol 155:481–489CrossRefPubMed Moratorio G, Obal G, Dubra A, Correa A, Bianchi S, Buschiazzo A, Cristina J, Pritsch O (2010) Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes. Arch Virol 155:481–489CrossRefPubMed
29.
Zurück zum Zitat Ababneh MM, Al-Rukibat RK, Hananeh WM, Nasar AT, Al-Zghoul MB (2012) Detection and molecular characterization of bovine leukemia viruses from Jordan. Arch Virol 157:2343–2348CrossRefPubMed Ababneh MM, Al-Rukibat RK, Hananeh WM, Nasar AT, Al-Zghoul MB (2012) Detection and molecular characterization of bovine leukemia viruses from Jordan. Arch Virol 157:2343–2348CrossRefPubMed
30.
Zurück zum Zitat Yang Y, Kelly PJ, Bai J, Zhang R, Wang C (2016) First molecular characterization of bovine leukemia virus infections in the Caribbean. PLoS One 11:e0168379CrossRefPubMedPubMedCentral Yang Y, Kelly PJ, Bai J, Zhang R, Wang C (2016) First molecular characterization of bovine leukemia virus infections in the Caribbean. PLoS One 11:e0168379CrossRefPubMedPubMedCentral
31.
Zurück zum Zitat Benavides B, Munoz S, Ceriani C (2017) Molecular analysis of a fragment of bovine leukemia virus env gene by nested-PCR in dairy cows from Pasto, Nariño. Rev Med Vet 33:67–75 Benavides B, Munoz S, Ceriani C (2017) Molecular analysis of a fragment of bovine leukemia virus env gene by nested-PCR in dairy cows from Pasto, Nariño. Rev Med Vet 33:67–75
32.
Zurück zum Zitat Pluta A, Rola-Łuszczak M, Kubiś P, Balov S, Moskalik R, Choudhury B, Kuźmak J (2017) Molecular characterization of bovine leukemia virus from Moldovan dairy cattle. Arch Virol 162:1563–1576CrossRefPubMedPubMedCentral Pluta A, Rola-Łuszczak M, Kubiś P, Balov S, Moskalik R, Choudhury B, Kuźmak J (2017) Molecular characterization of bovine leukemia virus from Moldovan dairy cattle. Arch Virol 162:1563–1576CrossRefPubMedPubMedCentral
33.
Zurück zum Zitat Dube S, Dolcini G, Abbott L, Mehta S, Dube D, Gutierrez S, Ceriani C, Esteban E, Ferrer J, Poiesz B (2000) The complete genomic sequence of a BLV strain from a Holstein cow from Argentina. Virology 277:379–386CrossRefPubMed Dube S, Dolcini G, Abbott L, Mehta S, Dube D, Gutierrez S, Ceriani C, Esteban E, Ferrer J, Poiesz B (2000) The complete genomic sequence of a BLV strain from a Holstein cow from Argentina. Virology 277:379–386CrossRefPubMed
34.
Zurück zum Zitat Gatot JS, Callebaut I, Van Lint C, Demonté D, Kerkhofs P, Portetelle D, Burny A, Willems L, Kettmann R (2002) Bovine leukemia virus SU protein interacts with zinc, and mutations within two interacting regions differently affect viral fusion and infectivity in vivo. J Virol 76:7956–7967CrossRefPubMedPubMedCentral Gatot JS, Callebaut I, Van Lint C, Demonté D, Kerkhofs P, Portetelle D, Burny A, Willems L, Kettmann R (2002) Bovine leukemia virus SU protein interacts with zinc, and mutations within two interacting regions differently affect viral fusion and infectivity in vivo. J Virol 76:7956–7967CrossRefPubMedPubMedCentral
Metadaten
Titel
Molecular detection and characterization of genotype 1 bovine leukemia virus from beef cattle in the traditional sector in Zambia
verfasst von
Mundia M. Phiri
Evans Kaimoyo
Katendi Changula
Isaac Silwamba
Herman M. Chambaro
Penjaninge Kapila
Masahiro Kajihara
Martin Simuunza
John Bwalya Muma
Girja S. Pandey
Ayato Takada
Aaron S. Mweene
Simbarashe Chitanga
Edgar Simulundu
Publikationsdatum
12.07.2019
Verlag
Springer Vienna
Erschienen in
Archives of Virology / Ausgabe 10/2019
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-019-04350-6

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