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Erschienen in: Pediatric Radiology 11/2013

01.11.2013 | Original Article

MR imaging of children and young adults with classic findings of osteonecrosis on unenhanced MR images: do contrast-enhanced sequences help?

verfasst von: Lamya A. Atweh, Robert C. Orth, R. Paul Guillerman, Wei Zhang, J. Herman Kan

Erschienen in: Pediatric Radiology | Ausgabe 11/2013

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Abstract

Background

The added value of routine contrast-enhanced MR imaging in children with classic findings of osteonecrosis on unenhanced MR images has not been determined.

Objective

Our purpose was to determine the added value of routine contrast-enhanced MR sequences for identifying complications of osteonecrosis.

Material and methods

Sixty-four patients who underwent 139 contrast-enhanced MR examinations were retrospectively identified. Unenhanced images and subsequently both unenhanced and enhanced images were reviewed in consensus. The location of osteonecrosis and the presence of complicating features (epiphyseal collapse, marrow edema, joint effusion, soft tissue edema) were recorded. Cohen’s kappa coefficients (κ) were calculated to assess agreement.

Results

A diagnosis of classic osteonecrosis was made in 22.3% of unenhanced examinations and 28.1% of enhanced examinations (κ = 0.734, P < 0.001). Among patients with complicated osteonecrosis, unenhanced images interpreted without and with contrast-enhanced images showed epiphyseal collapse in 51.2% and 42.5% (κ = 0.796, P < 0.001), marrow edema in 50.4% and 46.8% (κ = 0.727, P < 0.001), joint effusion in 44.9% and 51.2% (κ = 0.686, P < 0.001), and soft tissue edema in 12.2% and 10.1% (κ = 0.674, P < 0.001).

Conclusion

The high observed agreement between the unenhanced MR images interpreted without and with contrast-enhanced images shows little marginal benefit from the use of routine contrast-enhanced imaging in children and young adults with classic findings of osteonecrosis on unenhanced MR images.
Literatur
1.
Zurück zum Zitat Mikhael MA, Paige ML, Widen AL (1987) Magnetic resonance imaging and the diagnosis of avascular necrosis of the femoral head. Comput Radiol 11:157–163PubMedCrossRef Mikhael MA, Paige ML, Widen AL (1987) Magnetic resonance imaging and the diagnosis of avascular necrosis of the femoral head. Comput Radiol 11:157–163PubMedCrossRef
2.
Zurück zum Zitat Vande Berg B, Malghem J, Labaisse MA et al (1992) Avascular necrosis of the hip: comparison of contrast-enhanced and nonenhanced MR imaging with histologic correlation. Work in progress. Radiology 182:445–450 Vande Berg B, Malghem J, Labaisse MA et al (1992) Avascular necrosis of the hip: comparison of contrast-enhanced and nonenhanced MR imaging with histologic correlation. Work in progress. Radiology 182:445–450
3.
Zurück zum Zitat Mitchell DG, Rao VM, Dalinka MK et al (1987) Femoral head avascular necrosis: correlation of MR imaging, radiographic staging, radionuclide imaging, and clinical findings. Radiology 162:709–715PubMed Mitchell DG, Rao VM, Dalinka MK et al (1987) Femoral head avascular necrosis: correlation of MR imaging, radiographic staging, radionuclide imaging, and clinical findings. Radiology 162:709–715PubMed
4.
Zurück zum Zitat Totty WG, Murphy WA, Ganz WI et al (1984) Magnetic resonance imaging of the normal and ischemic femoral head. AJR Am J Roentgenol 143:1273–1280PubMedCrossRef Totty WG, Murphy WA, Ganz WI et al (1984) Magnetic resonance imaging of the normal and ischemic femoral head. AJR Am J Roentgenol 143:1273–1280PubMedCrossRef
5.
Zurück zum Zitat Chan WP, Liu Y-J, Huang G-S et al (2011) Relationship of idiopathic osteonecrosis of the femoral head to perfusion changes in the proximal femur by dynamic contrast-enhanced MRI. AJR Am J Roentgenol 196:637–643PubMedCrossRef Chan WP, Liu Y-J, Huang G-S et al (2011) Relationship of idiopathic osteonecrosis of the femoral head to perfusion changes in the proximal femur by dynamic contrast-enhanced MRI. AJR Am J Roentgenol 196:637–643PubMedCrossRef
6.
Zurück zum Zitat Nadel SN, Debatin JF, Richardson WJ et al (1992) Detection of acute avascular necrosis of the femoral head in dogs: dynamic contrast-enhanced MR imaging vs. spin-echo and STIR sequences. AJR Am J Roentgenol 159:1255–1261PubMedCrossRef Nadel SN, Debatin JF, Richardson WJ et al (1992) Detection of acute avascular necrosis of the femoral head in dogs: dynamic contrast-enhanced MR imaging vs. spin-echo and STIR sequences. AJR Am J Roentgenol 159:1255–1261PubMedCrossRef
7.
Zurück zum Zitat Vande Berge BE, Malghem JJ, Labaisse MA et al (1993) MR imaging of avascular necrosis and transient marrow edema of the femoral head. Radiographics 13:501–520 Vande Berge BE, Malghem JJ, Labaisse MA et al (1993) MR imaging of avascular necrosis and transient marrow edema of the femoral head. Radiographics 13:501–520
8.
Zurück zum Zitat Imhof H, Breitenseher M, Trattnig S et al (1997) Imaging of avascular necrosis of bone. Eur Radiol 7:180–186PubMedCrossRef Imhof H, Breitenseher M, Trattnig S et al (1997) Imaging of avascular necrosis of bone. Eur Radiol 7:180–186PubMedCrossRef
9.
Zurück zum Zitat Yamaguchi R, Yamamoto T, Motomura G et al (2011) MRI-detected double low-intensity bands in osteonecrosis of the femoral head. J Orthop Sci 16:471–475PubMedCrossRef Yamaguchi R, Yamamoto T, Motomura G et al (2011) MRI-detected double low-intensity bands in osteonecrosis of the femoral head. J Orthop Sci 16:471–475PubMedCrossRef
10.
Zurück zum Zitat Seiler JG III, Christie MJ, Homra L (1989) Correlation of the findings of magnetic resonance imaging with those of bone biopsy in patients who have stage-I or II ischemic necrosis of the femoral head. J Bone Joint Surg 71A:28–32 Seiler JG III, Christie MJ, Homra L (1989) Correlation of the findings of magnetic resonance imaging with those of bone biopsy in patients who have stage-I or II ischemic necrosis of the femoral head. J Bone Joint Surg 71A:28–32
11.
Zurück zum Zitat Mahnken AH, Staatz G, Ihme N et al (2002) MR signal intensity characteristics in Legg-Calve-Perthes disease. Value of fat-suppressed (STIR) images and contrast-enhanced T1-weighted images. Acta Radiol 43:329–335PubMedCrossRef Mahnken AH, Staatz G, Ihme N et al (2002) MR signal intensity characteristics in Legg-Calve-Perthes disease. Value of fat-suppressed (STIR) images and contrast-enhanced T1-weighted images. Acta Radiol 43:329–335PubMedCrossRef
12.
Zurück zum Zitat Uberoi R, Tai G, Hughes PM (1994) Gadolinium-DTPA-enhanced MRI in the evaluation of osteonecrosis. Clin Radiol 49:645–648PubMedCrossRef Uberoi R, Tai G, Hughes PM (1994) Gadolinium-DTPA-enhanced MRI in the evaluation of osteonecrosis. Clin Radiol 49:645–648PubMedCrossRef
13.
Zurück zum Zitat Sebag G, Ducou Le Pointe H, Klein I et al (1997) Dynamic gadolinium-enhanced subtraction MR imaging – a simple technique for the early diagnosis of Legg-Calve-Perthes disease: preliminary results. Pediatr Radiol 27:216–220PubMedCrossRef Sebag G, Ducou Le Pointe H, Klein I et al (1997) Dynamic gadolinium-enhanced subtraction MR imaging – a simple technique for the early diagnosis of Legg-Calve-Perthes disease: preliminary results. Pediatr Radiol 27:216–220PubMedCrossRef
Metadaten
Titel
MR imaging of children and young adults with classic findings of osteonecrosis on unenhanced MR images: do contrast-enhanced sequences help?
verfasst von
Lamya A. Atweh
Robert C. Orth
R. Paul Guillerman
Wei Zhang
J. Herman Kan
Publikationsdatum
01.11.2013
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Radiology / Ausgabe 11/2013
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-013-2714-1

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