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Erschienen in: Archives of Gynecology and Obstetrics 3/2011

01.03.2011 | Short Communication

MRI diagnosis and follow-up of hepatic infarction in a patient with antiphospholipid syndrome in early pregnancy

verfasst von: Boris Guiu, Romaric Loffroy, Jean-Pierre Cercueil, Paul Sagot, Denis Krausé, Hervé Tixier

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 3/2011

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Abstract

Hepatic infarction is rare in hemolysis, elevated liver enzymes, and low platelets syndrome. We described a case of a 24-year-old woman who was admitted at week 17 of pregnancy with an antiphospholipid syndrome. Magnetic resonance imaging was the imaging modality of choice for diagnosing hepatic infarction, guiding treatment, ensuring the early detection of bleeding, and monitoring liver recovery.
Literatur
1.
Zurück zum Zitat Stella CL, Malik KM, Sibai BM (2008) HELLP syndrome: an atypical presentation. Am J Obstet Gynecol 198(5):e6–e8CrossRefPubMed Stella CL, Malik KM, Sibai BM (2008) HELLP syndrome: an atypical presentation. Am J Obstet Gynecol 198(5):e6–e8CrossRefPubMed
2.
Zurück zum Zitat Pauzner R, Dulitzky M, Carp H, Mayan H, Kenett R, Farfel Z et al (2003) Hepatic infarctions during pregnancy are associated with the antiphospholipid syndrome and in addition with complete or incomplete HELLP syndrome. J Thromb Haemost 1(8):1758–1763CrossRefPubMed Pauzner R, Dulitzky M, Carp H, Mayan H, Kenett R, Farfel Z et al (2003) Hepatic infarctions during pregnancy are associated with the antiphospholipid syndrome and in addition with complete or incomplete HELLP syndrome. J Thromb Haemost 1(8):1758–1763CrossRefPubMed
3.
Zurück zum Zitat Barton JR, Riely CA, Adamec TA, Shanklin DR, Khoury AD, Sibai BM (1992) Hepatic histopathologic condition does not correlate with laboratory abnormalities in HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count). Am J Obstet Gynecol 167(6):1538–1543PubMed Barton JR, Riely CA, Adamec TA, Shanklin DR, Khoury AD, Sibai BM (1992) Hepatic histopathologic condition does not correlate with laboratory abnormalities in HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count). Am J Obstet Gynecol 167(6):1538–1543PubMed
4.
Zurück zum Zitat Sibai BM, Ramadan MK, Usta I, Salama M, Mercer BM, Friedman SA (1993) Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome). Am J Obstet Gynecol 169(4):1000–1006PubMed Sibai BM, Ramadan MK, Usta I, Salama M, Mercer BM, Friedman SA (1993) Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome). Am J Obstet Gynecol 169(4):1000–1006PubMed
5.
Zurück zum Zitat Alsulyman OM, Castro MA, Zuckerman E, McGehee W, Goodwin TM (1996) Preeclampsia and liver infarction in early pregnancy associated with the antiphospholipid syndrome. Obstet Gynecol 88(4 Pt 2):644–646CrossRefPubMed Alsulyman OM, Castro MA, Zuckerman E, McGehee W, Goodwin TM (1996) Preeclampsia and liver infarction in early pregnancy associated with the antiphospholipid syndrome. Obstet Gynecol 88(4 Pt 2):644–646CrossRefPubMed
6.
Zurück zum Zitat Sibai BM (1990) The HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): much ado about nothing? Am J Obstet Gynecol 162(2):311–316PubMed Sibai BM (1990) The HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): much ado about nothing? Am J Obstet Gynecol 162(2):311–316PubMed
7.
Zurück zum Zitat Sibai BM (2004) Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol 103(5 Pt 1):981–991CrossRefPubMed Sibai BM (2004) Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol 103(5 Pt 1):981–991CrossRefPubMed
8.
Zurück zum Zitat Delluc C, Costedoat-Chalumeau N, Saadoun D, Vauthier-Brouzes D, Wechsler B, Piette JC (2008) Elevation of alkaline phosphatase in a pregnant patient with antiphospholipid syndrome: HELLP syndrome or not? Rheumatology (Oxford) 47(4):554–555CrossRef Delluc C, Costedoat-Chalumeau N, Saadoun D, Vauthier-Brouzes D, Wechsler B, Piette JC (2008) Elevation of alkaline phosphatase in a pregnant patient with antiphospholipid syndrome: HELLP syndrome or not? Rheumatology (Oxford) 47(4):554–555CrossRef
9.
Zurück zum Zitat Sibai BM, Stella CL (2009) Diagnosis and management of atypical preeclampsia-eclampsia. Am J Obstet Gynecol 200(5):481.e1–481.e7CrossRef Sibai BM, Stella CL (2009) Diagnosis and management of atypical preeclampsia-eclampsia. Am J Obstet Gynecol 200(5):481.e1–481.e7CrossRef
10.
Zurück zum Zitat von Tempelhoff GF, Heilmann L, Spanuth E, Kunzmann E, Hommel G (2000) Incidence of the factor V Leiden-mutation, coagulation inhibitor deficiency, and elevated antiphospholipid-antibodies in patients with preeclampsia or HELLP-syndrome. Hemolysis, elevated liver-enzymes, low platelets. Thromb Res 100(4):363–365CrossRef von Tempelhoff GF, Heilmann L, Spanuth E, Kunzmann E, Hommel G (2000) Incidence of the factor V Leiden-mutation, coagulation inhibitor deficiency, and elevated antiphospholipid-antibodies in patients with preeclampsia or HELLP-syndrome. Hemolysis, elevated liver-enzymes, low platelets. Thromb Res 100(4):363–365CrossRef
11.
Zurück zum Zitat Cervera R, Font J, Gomez-Puerta JA, Espinosa G, Cucho M, Bucciarelli S et al (2005) Validation of the preliminary criteria for the classification of catastrophic antiphospholipid syndrome. Ann Rheum Dis 64(8):1205–1209CrossRefPubMed Cervera R, Font J, Gomez-Puerta JA, Espinosa G, Cucho M, Bucciarelli S et al (2005) Validation of the preliminary criteria for the classification of catastrophic antiphospholipid syndrome. Ann Rheum Dis 64(8):1205–1209CrossRefPubMed
12.
Zurück zum Zitat O’Brien J, Buckley O, Munk PL, Torreggiani WC (2007) An unusual case of elevated liver enzymes (2006: 10b). Hepatic necrosis following HELLP syndrome. Eur Radiol 17(1):289–291CrossRefPubMed O’Brien J, Buckley O, Munk PL, Torreggiani WC (2007) An unusual case of elevated liver enzymes (2006: 10b). Hepatic necrosis following HELLP syndrome. Eur Radiol 17(1):289–291CrossRefPubMed
13.
Zurück zum Zitat Kronthal AJ, Fishman EK, Kuhlman JE, Bohlman ME (1990) Hepatic infarction in preeclampsia. Radiology 177(3):726–728PubMed Kronthal AJ, Fishman EK, Kuhlman JE, Bohlman ME (1990) Hepatic infarction in preeclampsia. Radiology 177(3):726–728PubMed
14.
Zurück zum Zitat Seige M, Schweigart U, Moessmer G, Schneider KT, Classen M (1998) Extensive hepatic infarction caused by thrombosis of right portal vein branches and arterial vasospasm in HELLP syndrome associated with homozygous factor V Leiden. Am J Gastroenterol 93(3):473–474PubMed Seige M, Schweigart U, Moessmer G, Schneider KT, Classen M (1998) Extensive hepatic infarction caused by thrombosis of right portal vein branches and arterial vasospasm in HELLP syndrome associated with homozygous factor V Leiden. Am J Gastroenterol 93(3):473–474PubMed
15.
Zurück zum Zitat Smith GS, Birnbaum BA, Jacobs JE (1998) Hepatic infarction secondary to arterial insufficiency in native livers: CT findings in 10 patients. Radiology 208(1):223–229PubMed Smith GS, Birnbaum BA, Jacobs JE (1998) Hepatic infarction secondary to arterial insufficiency in native livers: CT findings in 10 patients. Radiology 208(1):223–229PubMed
Metadaten
Titel
MRI diagnosis and follow-up of hepatic infarction in a patient with antiphospholipid syndrome in early pregnancy
verfasst von
Boris Guiu
Romaric Loffroy
Jean-Pierre Cercueil
Paul Sagot
Denis Krausé
Hervé Tixier
Publikationsdatum
01.03.2011
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 3/2011
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-010-1467-4

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