Background
Methods
Study cohort
Study sites
Study protocol
Parameter | Site I | Site II | Site III |
---|---|---|---|
Field strength (T) | 3 | 3 | 3 |
Vendor | Siemens | Siemens | Siemens |
Model | SkyraFIT | PrismaFIT | PrismaFIT |
RF-coil | 18-channel | 32-channel | 18-channel |
Bore size (cm) | 70 | 60 | 60 |
Bore size (cm) | 70 | 60 | 60 |
T1 scan parameters | |||
Sequence | 5-3-3 MOLLI | 5-3-3 MOLLI | 5-3-3 MOLLI |
Slice thickness (mm) | 6.0 | 6.0 | 6.0 |
Voxel size (mm × mm) | 1.4 × 1.4 | 1.4 × 1.4 | 1.4 × 1.4 |
Field of view (mm) | 360 | 360 | 360 |
Echo time (ms) | 1.12 | 1.12 | 1.12 |
Repetition time (ms) | 3.9 | 3.9 | 3.9 |
Flip angle (o) | 35 | 35 | 35 |
Bandwith (Hz/Px) | 1085 | 1085 | 1085 |
Acceleration factor | 2 | 2 | 2 |
T2 scan parameters | |||
Sequence | FLASH | FLASH | FLASH |
Slice thickness (mm) | 6.0 | 6.0 | 6.0 |
Voxel size (mm × mm) | 1.9 × 1.9 | 1.9 × 1.9 | 1.9 × 1.9 |
Field of view (mm) | 360 | 360 | 360 |
Echo time (ms) | 1.32 | 1.32 | 1.32 |
Repetition time (ms) | 3.6 | 3.6 | 3.6 |
Flip angle (degrees) | 12 | 12 | 12 |
Bandwidth (Hz/Px) | 1184 | 1184 | 1184 |
Acceleration factor | 2 | 2 | 2 |
CMR analysis
Statistical analysis
Results
Study cohort
Parameter | Site I | Site II | Site III |
---|---|---|---|
N = | 18 | 19 | 18 |
Female/Male | 8/10 | 8/11 | 7/11 |
Age (years) | 26.3 ± 6.1 | 26.1 ± 6 | 26.3 ± 6.2 |
Height (m) | 1.8 ± 0.1 | 1.8 ± 0.1 | 1.8 ± 0.1 |
Weight (kg) | 69.3 ± 11.1 | 70.2 ± 11.4 | 70.1 ± 11.7 |
Body mass index (kg/m2) | 21.5 ± 2.4 | 21.7 ± 2.4 | 21.5 ± 2.4 |
Body surface area (m2) | 1.9 ± 0.2 | 1.9 ± 0.2 | 1.9 ± 0.2 |
Heart rate | 68.6 ± 12.9 | 63.8 ± 10.1 | 69.1 ± 9 |
Systolic blood pressure (mmHg) | 123.2 ± 12.4 | 119.5 ± 7.4 | 123.1 ± 9.7 |
Diastolic blood pressure (mmHg) | 69.7 ± 14.4 | 68.7 ± 11.8 | 77.5 ± 9.5 |
CMR results—quality survey
CMR results—travelling volunteers
Parameter | Site I | Site II | Site III | p value for sites I vs. II vs. III |
---|---|---|---|---|
T1 global (ms) | 1207 ± 32 [1192–1222] | 1207 ± 40 [1184–1225] | 1219 ± 26 [1207–1232] | 0.067 |
T1 basal (ms) | 1212 ± 27 [1200–1225] | 1210 ± 33 [1194–1226] | 1224 ± 27 [1210–1237] | 0.178 |
T1 midventricular (ms) | 1205 ± 34 [1189–1220] | 1207 ± 40 [1188–1225] | 1219 ± 26 [1206–1231] | 0.028* |
T1 apical (ms) | 1203 ± 40 [1184–1221] | 1199 ± 51 [1175–1222] | 1214 ± 33 [1198–1229] | 0.089 |
T1 basal septum (ms) | 1227 ± 36 [1211–1244] | 1227 ± 31 [1213–1241] | 1240 ± 36 [1223–1257] | 0.267 |
T1 midventricular septum (ms) | 1222 ± 39 [1206–1238] | 1224 ± 37 [1208–1241] | 1232 ± 29 [1218–1245] | 0.202 |
T2 global (ms) | 40 ± 2 [39–41] | 40 ± 1 [39–41] | 39 ± 2 [39–41] | 0.543 |
T2 basal (ms) | 39 ± 2 [38–40] | 39 ± 1 [39–40] | 39 ± 2 [38–40] | 0.546 |
T2 midventricular (ms) | 40 ± 2 [39–41] | 40 ± 2 [39–41] | 40 ± 2 [39–41] | 0.954 |
T2 apical (ms) | 40 ± 3 [39–42] | 41 ± 2 [40–42] | 40 ± 2 [39–41] | 0.143 |
T2 basal septum (ms) | 40 ± 3 [39–41] | 40 ± 1 [39–41] | 40 ± 2 [39–41] | 0.815 |
T2 midventricular septum (ms) | 41 ± 3 [40–43] | 41 ± 2 [40–42] | 41 ± 3 [40–42] | 0.898 |
Parameter | Site I vs. site II | Site I vs. site III | Site II vs. site III |
---|---|---|---|
T1 global (ms/%) | 1.4 [− 3.2;6.1] / 0.1 [− 0.9; 1] | − 15.8 [− 20.5; -11.5)] / 1.2 [0.2; 2.1] | − 15.7 [− 21.0; − 10.4)]/ 1.1 [− 0.1; 2.3] |
T1 basal (ms/%) | − 0.6 [− 8.5; 7.2] / 0.1 [− 1.0; 1.2] | − 15.9 [− 22.9; − 8.9)] / 1 [− 0.1; 2.0] | − 14.3 [− 23.3; − 5.4)] / 1.1 [− 0.4; 2.6] |
T1 midventricular (ms/%) | 0.1 [− 6.7; 6.9] / 0.3 [− 0.7; 1.3] | − 16.3 [− 22.8; − 9.7] / 1.5[0.5; 2.4] | − 14.8 [− 22.5; − 7.2] /1.1 [0.1; 2.1] |
T1 apical (ms/%) | 7.2 [− 2.5; 16.9] / − 0.3 [− 1.3; 0.7] | − 14.7 [− 24.4; 5.1)] / 1.1 [0.01; 2.2] | − 19.1 [− 30.7; − 7.4)]/ 1.3 [− 0.2; 2.8] |
T2 global (ms/%) | − 0.4 [− 0.7; 0.0] / 0.8 [− 1.3; 2.9] | 1.1 [0.2; 2.0] / 0.0 [− 2.3–2.3] | 0.6 [− 0.2; 0.9] / − 1.3 [− 2.8; 0.2] |
T2 basal (ms/%) | − 0.4 [− 0.9; 0.2] / 0.9 [− 1.1; 3.0] | 0.3 [− 0.7; 1.3] / 0.3 [− 2.2; 2.7] | 0.2 [− 0.4; 0.7] / − 0.6 [− 2.6; 1.5] |
T2 midventricular (ms/%) | 0.0 [− 0.6; 0.5] / 0.05 [− 2.3; 2.4] | 1.1 [− 0.5; 2.7] / 0.1 [− 2.3; 2.6] | − 0.4 [− 1.3; 0.5] − 0.7 [− 2.8; 1.4] |
T2 apical (ms/%) | − 0.9 [− 1.8; 0.0] / 2.1 [− 1.0; 5.3] | 2.2 [− 0.1; 4.5] / − 0.8 [− 4.2; 2.7] | 1.8 [0.5; 3.2] / − 3.4 [− 5.5; − 1.4] |