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Erschienen in: European Journal of Applied Physiology 5/2008

01.07.2008 | Original Article

Myosin heavy chain isoform distribution in single fibres of bodybuilders

verfasst von: Nikolaos Kesidis, Thomas I. Metaxas, Ioannis S. Vrabas, Panagiotis Stefanidis, Efstratios Vamvakoudis, Kosmas Christoulas, Athanasios Mandroukas, Dimitrios Balasas, Konstantinos Mandroukas

Erschienen in: European Journal of Applied Physiology | Ausgabe 5/2008

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Abstract

The purpose of this study was to investigate the long-term effects of high intensity resistance training on myosin heavy chain (MHC) isoform composition of single fibres. Muscle biopsies were obtained from the right vastus lateralis of eight bodybuilders (BB) and seven physical education students (PES). Histochemical analyses were used to determine the fibre type distribution and the fibre cross-sectional area. MHC isoform composition of single fibres was determined with protein electrophoresis. The percentage of fibres expressing MHC IIA and MHC I/IIA was larger in BB (P < 0.05), while MHC IIX was completely absent (P < 0.05). In contrast, myofibrilar ATPase histochemistry only revealed a significantly lower percentage of type IIX fibres in BB (P < 0.05). The muscle fibre profile in the vastus lateralis muscle of BB may represent an adaptation based on the mechanical and biochemical demands of the long-term resistance training.
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Metadaten
Titel
Myosin heavy chain isoform distribution in single fibres of bodybuilders
verfasst von
Nikolaos Kesidis
Thomas I. Metaxas
Ioannis S. Vrabas
Panagiotis Stefanidis
Efstratios Vamvakoudis
Kosmas Christoulas
Athanasios Mandroukas
Dimitrios Balasas
Konstantinos Mandroukas
Publikationsdatum
01.07.2008
Verlag
Springer-Verlag
Erschienen in
European Journal of Applied Physiology / Ausgabe 5/2008
Print ISSN: 1439-6319
Elektronische ISSN: 1439-6327
DOI
https://doi.org/10.1007/s00421-008-0751-5

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