Background
Methods
Participants
ASD subjects | Gender | Age | Dominance | FSIQ standard score | Vocabulary T-score | Matrix reasoning T-score | ADI-R social | ADI-R communication | ADIR repetitive behaviors |
---|---|---|---|---|---|---|---|---|---|
1 | M | 19.00 | R | 131.0 | 77.00 | 57.00 | 14.00 | 16.00 | 9.00 |
2 | F | 13.00 | L | 96.0 | 35.00 | 61.00 | 23.00 | 15.00 | 4.00 |
3 | M | 13.00 | R | 93.0 | 39.00 | 53.00 | 27.00 | 24.00 | 6.00 |
4 | M | 15.00 | R | 137.0 | 67.00 | 73.00 | 20.00 | 14.00 | 8.00 |
5 | M | 19.00 | R | 144.0 | 77.00 | 67.00 | 17.00 | 9.00 | 3.00 |
6 | F | 16.00 | R | 119.0 | 62.00 | 60.00 | 20.00 | 11.00 | 5.00 |
7 | M | 24.00 | R | Discontinued | 66.00 | 24.00 | 18.00 | 3.00 | |
8 | F | 16.00 | R | 79.0 | 44.00 | 28.00 | 20.00 | 18.00 | 6.00 |
9 | M | 16.00 | R | 118.0 | 61.00 | 60.00 | 13.00 | 10.00 | 7.00 |
10 | M | 15.00 | R | 92.0 | 64.00 | 28.00 | 17.00 | 16.00 | 8.00 |
Mean
| 16.60 | 112.1 | 58.44 | 55.30 | 19.50 | 15.10 | 5.90 | ||
SD
| 3.31 | 22.9 | 15.61 | 15.42 | 4.40 | 4.46 | 2.13 | ||
Range
| 11-24 | 79-144 | 35-77 | 28-73 | |||||
Control subjects
| |||||||||
1 | M | 21.00 | R | 122.0 | 64.00 | 61.00 | |||
2 | F | 13.00 | R | 120.0 | 66.00 | 57.00 | |||
3 | M | 13.00 | R | 122.0 | 59.00 | 66.00 | |||
4 | M | 15.00 | R | 118.0 | 60.00 | 60.00 | |||
5 | M | 19.00 | R | 117.0 | 58.00 | 60.00 | |||
6 | F | 19.00 | L | 119.0 | 59.00 | 63.00 | |||
7 | M | 18.00 | R | 100.0 | 44.00 | 57.00 | |||
8 | F | 18.00 | R | 117.0 | 60.00 | 57.00 | |||
Mean
| 17.00 | 116.9 | 58.75 | 60.13 | |||||
SD
| 2.98 | 7.1 | 6.56 | 3.23 | |||||
Range
| 13-21 | 100-122 | 44-66 | 57-66 | |||||
Mann–Whitney U P value
| 0.11 | 0.76 | 0.70 | 0.54 | 0.90 |
MEG data acquisition and preprocessing
Gaze cueing paradigm
MEG coherence analysis
Group difference testing
Results
Behavioral data
Total correct responses | Reaction time for correct responses | ||
---|---|---|---|
ASD | Neurotypical | ASD | Neurotypical |
47 | 45 | 673 | 915 |
43 | 46 | 1,044 | 916 |
46 | 47 | 818 | 887 |
37 | 44 | 1,096 | 717 |
45 | 45 | 683 | 718 |
38 | 45 | 936 | 855 |
53 | 45 | 935 | 862 |
45 | 38 | 761 | 929 |
45 | 557 | ||
41 | 1,136 | ||
M (SD) 44.00 (4.62) | M (SD) 44.38 (2.72) | M (SD) 863.90 (196.26) | M (SD) 849.88 (88.15) |
MEG analysis: coherence imaging of connectivity
Direct gaze condition
Brain region pairs (pathway) for direct gaze | z-score | P value |
---|---|---|
Regions with higher coherence in NT | ||
R. middle frontal gyrus and R. superior temporal gyrus | -4.69 | <0.0001 |
L. lateral orbitofrontal gyrus and R. precentral gyrus | -4.44 | <0.0001 |
L. lateral orbitofrontal gyrus and R. postcentral gyrus | -4.41 | <0.0001 |
R. inferior frontal gyrus and R. middle frontal gyrus | -4.33 | <0.0001 |
L. superior frontal gyrus and R. superior temporal gyrus | -4.32 | <0.0001 |
L. inferior frontal gyrus and R. postcentral gyrus | -4.26 | <0.0001 |
L. inferior frontal gyrus and R. precentral gyrus | -4.14 | <0.0001 |
R. middle frontal gyrus and R. postcentral gyrus | -4.19 | <0.0001 |
L. middle frontal gyrus and R. precentral gyrus | -4.11 | 0.0001 |
L. middle frontal gyrus and R. postcentral gyrus | -4.12 | 0.0001 |
Regions with higher coherence in ASD | ||
L. angular gyrus and L. middle occipital gyrus | 5.10 | <0.0001 |
L. angular gyrus and R. middle occipital gyrus | 4.77 | <0.0001 |
L. angular gyrus and L. superior occipital gyrus | 4.09 | <0.0001 |
L. angular gyrus and R. cuneus | 4.02 | 0.0001 |
L. angular gyrus and L. inferior occipital gyrus | 4.02 | 0.0001 |
L. postcentral gyrus and L. superior occipital gyrus | 3.86 | 0.0001 |
L. angular gyrus and R. inferior occipital gyrus | 3.85 | 0.0001 |
L. superior occipital gyrus and L. supramarginal gyrus | 3.85 | 0.0001 |
L. middle occipital gyrus and R. middle occipital gyrus | 3.84 | 0.0001 |
L. angular gyrus and L. supramarginal gyrus | 3.71 | 0.0002 |
Averted gaze condition
(A) Brain Region Pairs (Pathway) for 0 to 15 Hz | z-score | P value |
---|---|---|
Regions with higher coherence in NT | ||
R. inferior frontal gyrus and R. middle frontal gyrus | -5.23 | <0.0001 |
R. inferior frontal gyrus and R. superior frontal gyrus | -4.96 | <0.0001 |
L. lateral orbitofrontal gyrus and R. postcentral gyrus | -4.2 | <0.0001 |
R. superior frontal gyrus and R. superior temporal gyrus | -4.2 | <0.0001 |
R. postcentral gyrus and R. superior frontal gyrus | -4.07 | 0.00010 |
L. precentral gyrus and R. superior frontal gyrus | -4.02 | 0.00020 |
L. superior frontal gyrus and R. postcentral gyrus | -3.65 | 0.00030 |
L. inferior frontal gyrus and R. postcentral gyrus | -3.65 | 0.00040 |
L. lateral orbitofrontal gyrus and R. middle frontal gyrus | -3.61 | 0.00030 |
L. inferior frontal gyrus and R. inferior frontal gyrus | -3.61 | 0.00030 |
L. superior temporal gyrus and R. middle frontal gyrus | -3.55 | 0.00040 |
L. precentral gyrus and R. middle frontal gyrus | -3.52 | 0.00080 |
R. middle frontal gyrus and R. superior temporal gyrus | -3.51 | 0.00060 |
L. lateral orbitofrontal gyrus and R. supramarginal gyrus | -3.49 | 0.00060 |
R. middle frontal gyrus and R. postcentral gyrus | -3.49 | 0.00080 |
L. middle frontal gyrus and R. postcentral gyrus | -3.42 | 0.00100 |
L. lateral orbitofrontal gyrus and R. inferior frontal gyrus | -3.3 | 0.00130 |
L. middle frontal gyrus and R. inferior frontal gyrus | -3.27 | 0.00110 |
L. middle frontal gyrus and R. precentral gyrus | -3.27 | 0.00150 |
R. superior frontal gyrus and R. supramarginal gyrus | -3.26 | 0.00170 |
L. lateral orbitofrontal gyrus and R. precentral gyrus | -3.25 | 0.00130 |
L. superior temporal gyrus and R. superior frontal gyrus | -3.24 | 0.00120 |
L. precentral gyrus and L. superior frontal gyrus | -3.22 | 0.00190 |
R. precentral gyrus and R. superior frontal gyrus | -3.2 | 0.00150 |
R. middle frontal gyrus and R. superior frontal gyrus | -3.14 | 0.00170 |
L. lateral orbitofrontal gyrus and L. precentral gyrus | -3.14 | 0.00220 |
L. superior frontal gyrus and R. inferior frontal gyrus | -3.1 | 0.00200 |
L. inferior frontal gyrus and R. precentral gyrus | -3.08 | 0.00250 |
R. angular gyrus and R. superior frontal gyrus | -3.07 | 0.00320 |
L. inferior frontal gyrus and R. middle frontal gyrus | -3.05 | 0.00230 |
L. postcentral gyrus and R. superior frontal gyrus | -3.02 | 0.00320 |
L. inferior frontal gyrus and R. supramarginal gyrus | -3.02 | 0.00320 |
L. superior frontal gyrus and R. precentral gyrus | -3 | 0.00270 |
R. middle frontal gyrus and R. supramarginal gyrus | -2.92 | 0.00470 |
L. superior parietal gyrus and R. superior frontal gyrus | -2.88 | 0.00490 |
L. precuneus and R. superior frontal gyrus | -2.83 | 0.00730 |
L. inferior frontal gyrus and L. precentral gyrus | -2.82 | 0.00560 |
L. superior frontal gyrus and R. supramarginal gyrus | -2.81 | 0.00610 |
L. lateral orbitofrontal gyrus and R. angular gyrus | -2.8 | 0.00570 |
L. lateral orbitofrontal gyrus and L. superior parietal gyrus | -2.78 | 0.00650 |
L. middle orbitofrontal gyrus and R. postcentral gyrus | -2.78 | 0.00700 |
L. middle frontal gyrus and R. supramarginal gyrus | -2.78 | 0.00720 |
L. lateral orbitofrontal gyrus and L. precuneus | -2.76 | 0.00760 |
L. superior temporal gyrus and R. inferior frontal gyrus | -2.72 | 0.00660 |
L. middle frontal gyrus and L. precentral gyrus | -2.71 | 0.00880 |
R. middle frontal gyrus and R. precentral gyrus | -2.68 | 0.00850 |
L. superior frontal gyrus and R. superior temporal gyrus | -2.66 | 0.00780 |
Regions with higher coherence in ASD | ||
L. angular gyrus and L. inferior occipital gyrus | 4.86 | <0.0001 |
L. angular gyrus and R. lingual gyrus | 4.79 | <0.0001 |
L. middle occipital gyrus and R. cuneus | 4.7 | <0.0001 |
L. middle occipital gyrus and R. lingual gyrus | 4.51 | <0.0001 |
L. angular gyrus and L. middle occipital gyrus | 4.47 | <0.0001 |
L. angular gyrus and R. middle occipital gyrus | 4.46 | <0.0001 |
L. angular gyrus and R. cuneus | 4.38 | <0.0001 |
L. inferior occipital gyrus and R. lingual gyrus | 4.28 | <0.0001 |
L. angular gyrus and R. superior occipital gyrus | 4.17 | <0.0001 |
L. middle occipital gyrus and R. superior occipital gyrus | 4.16 | <0.0001 |
L. middle occipital gyrus and R. middle occipital gyrus | 4.11 | <0.0001 |
L. inferior occipital gyrus and R. cuneus | 4.01 | 0.00010 |
L. cuneus and R. lingual gyrus | 3.99 | 0.00010 |
L. middle occipital gyrus and R. superior parietal gyrus | 3.9 | 0.00010 |
R. lingual gyrus and R. middle occipital gyrus | 3.83 | 0.00010 |
L. inferior occipital gyrus and R. superior parietal gyrus | 3.74 | 0.00020 |
L. angular gyrus and R. inferior occipital gyrus | 3.72 | 0.00020 |
L. angular gyrus and L. cuneus | 3.68 | 0.00020 |
R. cuneus and R. middle occipital gyrus | 3.6 | 0.00040 |
L. middle occipital gyrus and R. inferior occipital gyrus | 3.59 | 0.00040 |
R. gyrus rectus and R. lingual gyrus | 3.57 | 0.00060 |
L. angular gyrus and L. lingual gyrus | 3.55 | 0.00040 |
L. middle temporal gyrus and R. lingual gyrus | 3.54 | 0.00040 |
L. angular gyrus and L. fusiform gyrus | 3.54 | 0.00060 |
R. cuneus and R. lingual gyrus | 3.51 | 0.00060 |
R. middle occipital gyrus and R. superior occipital gyrus | 3.47 | 0.00050 |
L. middle occipital gyrus and R. angular gyrus | 3.47 | 0.00050 |
L. middle occipital gyrus and R. middle temporal gyrus | 3.47 | 0.00050 |
L. superior temporal gyrus and R. cuneus | 3.45 | 0.00070 |
L. middle temporal gyrus and R. cuneus | 3.44 | 0.00070 |
L. lingual gyrus and R. lingual gyrus | 3.41 | 0.00070 |
L. inferior temporal gyrus and R. cuneus | 3.39 | 0.00070 |
L. inferior occipital gyrus and R. middle occipital gyrus | 3.34 | 0.00090 |
L. angular gyrus and L. inferior temporal gyrus | 3.34 | 0.00110 |
R. lingual gyrus and R. superior occipital gyrus | 3.32 | 0.00090 |
L. inferior occipital gyrus and R. superior occipital gyrus | 3.31 | 0.00090 |
L. postcentral gyrus and R. cuneus | 3.3 | 0.00100 |
L. fusiform gyrus and R. cuneus | 3.3 | 0.00110 |
L. angular gyrus and R. superior parietal gyrus | 3.26 | 0.00120 |
L. inferior temporal gyrus and R. lingual gyrus | 3.25 | 0.00120 |
L. inferior occipital gyrus and R. middle temporal gyrus | 3.23 | 0.00140 |
R. middle occipital gyrus and R. superior parietal gyrus | 3.21 | 0.00130 |
R. cuneus and R. superior occipital gyrus | 3.19 | 0.00150 |
L. cuneus and R. middle occipital gyrus | 3.19 | 0.00160 |
L. angular gyrus and L. middle temporal gyrus | 3.17 | 0.00160 |
L. superior temporal gyrus and R. lingual gyrus | 3.16 | 0.00170 |
L. angular gyrus and L. superior occipital gyrus | 3.12 | 0.00190 |
L. cuneus and R. cuneus | 3.1 | 0.00230 |
R. cuneus and R. gyrus rectus | 3.09 | 0.00240 |
L. cuneus and R. inferior occipital gyrus | 3.08 | 0.00210 |
L. angular gyrus and R. middle temporal gyrus | 3.04 | 0.00250 |
L. lingual gyrus and R. cuneus | 3.02 | 0.00280 |
L. cuneus and L. fusiform gyrus | 3.01 | 0.00290 |
L. inferior occipital gyrus and R. angular gyrus | 2.98 | 0.00300 |
L. cuneus and L. middle occipital gyrus | 2.98 | 0.00380 |
L. middle occipital gyrus and R. precuneus | 2.95 | 0.00320 |
L. postcentral gyrus and R. lingual gyrus | 2.94 | 0.00340 |
L. inferior occipital gyrus and L. middle occipital gyrus | 2.94 | 0.00480 |
L. postcentral gyrus and R. superior occipital gyrus | 2.88 | 0.00460 |
R. superior occipital gyrus and R. superior parietal gyrus | 2.87 | 0.00410 |
L. inferior occipital gyrus and R. inferior occipital gyrus | 2.86 | 0.00450 |
L. angular gyrus and R. angular gyrus | 2.85 | 0.00440 |
L. lingual gyrus and R. middle occipital gyrus | 2.83 | 0.00480 |
L. fusiform gyrus and R. lingual gyrus | 2.83 | 0.00490 |
L. middle occipital gyrus and R. lateral orbitofrontal gyrus | 2.81 | 0.00500 |
L. postcentral gyrus and L. superior occipital gyrus | 2.81 | 0.00530 |
R. lingual gyrus and R. superior parietal gyrus | 2.78 | 0.00540 |
L. cuneus and R. superior parietal gyrus | 2.78 | 0.00560 |
L. middle occipital gyrus and L. middle temporal gyrus | 2.76 | 0.00750 |
L. middle occipital gyrus and R. supramarginal gyrus | 2.75 | 0.00630 |
L. precentral gyrus and R. cuneus | 2.74 | 0.00630 |
R. lingual gyrus and R. middle temporal gyrus | 2.74 | 0.00680 |
R. inferior occipital gyrus and R. lingual gyrus | 2.73 | 0.00650 |
L. cuneus and R. superior occipital gyrus | 2.7 | 0.00740 |
L. angular gyrus and R. gyrus rectus | 2.69 | 0.00740 |
R. middle occipital gyrus and R. middle temporal gyrus | 2.69 | 0.00740 |
L. angular gyrus and L. superior temporal gyrus | 2.68 | 0.00740 |
L. cuneus and L. postcentral gyrus | 2.67 | 0.00770 |
L. angular gyrus and R. precuneus | 2.67 | 0.00790 |
L. middle occipital gyrus and R. superior temporal gyrus | 2.64 | 0.00850 |
(B) Brain region pairs (pathway) for 15 to 30 Hz
| z-score | P value |
Regions with higher coherence in NT | ||
R. middle frontal gyrus and R. superior temporal gyrus | -5.18 | <0.0001 |
R. inferior frontal gyrus and R. superior frontal gyrus | -5.18 | 0.0025 |
L. lateral orbitofrontal gyrus and R. precentral gyrus | -4.58 | <0.0001 |
R. inferior frontal gyrus and R. superior temporal gyrus | -4.55 | <0.0001 |
L. superior frontal gyrus and R. precentral gyrus | -4.21 | <0.0001 |
R. middle frontal gyrus and R. precentral gyrus | -4.13 | <0.0001 |
R. middle frontal gyrus and R. postcentral gyrus | -4.09 | <0.0001 |
L. superior frontal gyrus and R. superior temporal gyrus | -3.94 | <0.0001 |
L. superior frontal gyrus and R. postcentral gyrus | -3.92 | <0.0001 |
R. precentral gyrus and R. superior temporal gyrus | -3.9 | <0.0001 |
R. superior frontal gyrus and R. superior temporal gyrus | -3.9 | 0.0001 |
R. inferior frontal gyrus and R. precentral gyrus | -3.87 | 0.0001 |
R. inferior frontal gyrus and R. middle frontal gyrus | -3.84 | 0.0001 |
R. precentral gyrus and R. superior frontal gyrus | -3.76 | 0.0003 |
R. postcentral gyrus and R. superior frontal gyrus | -3.58 | 0.0005 |
L. middle frontal gyrus and R. precentral gyrus | -3.55 | 0.0005 |
L. inferior frontal gyrus and R. precentral gyrus | -3.48 | 0.0007 |
R. lateral orbitofrontal gyrus and R. precentral gyrus | -3.32 | 0.0009 |
L. lateral orbitofrontal gyrus and R. postcentral gyrus | -3.3 | 0.0001 |
R. middle orbitofrontal gyrus and R. precentral gyrus | -3.26 | 0.0017 |
R. postcentral gyrus and R. superior temporal gyrus | -3.22 | 0.0013 |
R. inferior frontal gyrus and R. postcentral gyrus | -3.22 | 0.0014 |
L. middle frontal gyrus and R. superior temporal gyrus | -3.17 | 0.0017 |
L. middle orbitofrontal gyrus and R. precentral gyrus | -3.16 | 0.0022 |
R. middle orbitofrontal gyrus and R. postcentral gyrus | -3.14 | 0.0024 |
L. middle frontal gyrus and R. postcentral gyrus | -3.1 | 0.0021 |
L. superior frontal gyrus and R. inferior frontal gyrus | -3.07 | 0.0022 |
Regions with higher coherence in ASD | ||
L. angular gyrus and L. middle occipital gyrus | 3.66 | 0.0003 |
L. superior occipital gyrus and L. supramarginal gyrus | 3.65 | 0.0003 |
L. middle occipital gyrus and L. middle temporal gyrus | 3.58 | 0.0004 |
L. angular gyrus and R. middle occipital gyrus | 3.51 | 0.0005 |
L. middle occipital gyrus and R. middle temporal gyrus | 3.48 | 0.0006 |
L. superior occipital gyrus and R. inferior occipital gyrus | 3.21 | 0.0014 |
L. angular gyrus and L. supramarginal gyrus | 3.19 | 0.0014 |
L. middle occipital gyrus and L. superior occipital gyrus | 3.15 | 0.0017 |
L. middle occipital gyrus and L. superior temporal gyrus | 3.08 | 0.0022 |
L. middle temporal gyrus and L. supramarginal gyrus | 3.08 | 0.0022 |
(C) Brain region pairs (pathway) for 30 to 45 Hz
| z-score | P value |
Regions with higher coherence in NT | ||
L. lateral orbitofrontal gyrus and R. precentral gyrus | -4.04 | 0.0001 |
L. middle frontal gyrus and R. precentral gyrus | -3.99 | 0.0001 |
R. middle frontal gyrus and R. superior temporal gyrus | -3.86 | 0.0002 |
L. inferior temporal gyrus and R. precentral gyrus | -3.79 | 0.0002 |
L. middle frontal gyrus and R. postcentral gyrus | -3.76 | 0.0003 |
R. middle frontal gyrus and R. postcentral gyrus | -3.74 | 0.0005 |
R. middle frontal gyrus and R. precentral gyrus | -3.72 | 0.0003 |
R. inferior frontal gyrus and R. middle frontal gyrus | -3.64 | 0.0003 |
L. middle frontal gyrus and R. superior temporal gyrus | -3.6 | 0.0003 |
L. inferior frontal gyrus and R. precentral gyrus | -3.6 | 0.0004 |
L. middle orbitofrontal gyrus and R. precentral gyrus | -3.59 | 0.0004 |
L. lateral orbitofrontal gyrus and R. postcentral gyrus | -3.53 | 0.0006 |
L. superior frontal gyrus and R. precentral gyrus | -3.46 | 0.0007 |
L. superior frontal gyrus and R. postcentral gyrus | -3.46 | 0.001 |
L. inferior frontal gyrus and R. postcentral gyrus | -3.44 | 0.0009 |
R. inferior frontal gyrus and R. precentral gyrus | -3.4 | 0.0007 |
L. lateral orbitofrontal gyrus and R. inferior frontal gyrus | -3.38 | 0.0007 |
R. inferior frontal gyrus and R. superior temporal gyrus | -3.37 | 0.0008 |
L. lateral orbitofrontal gyrus and R. middle frontal gyrus | -3.32 | 0.0009 |
L. superior frontal gyrus and R. superior temporal gyrus | -3.29 | 0.001 |
L. middle frontal gyrus and R. inferior frontal gyrus | -3.26 | 0.0011 |
L. inferior temporal gyrus and R. postcentral gyrus | -3.2 | 0.0014 |
R. inferior frontal gyrus and R. postcentral gyrus | -3.2 | 0.0016 |
L. middle orbitofrontal gyrus and L. precentral gyrus | -3.17 | 0.0017 |
L. middle orbitofrontal gyrus and R. postcentral gyrus | -3.16 | 0.002 |
L. superior frontal gyrus and R. inferior frontal gyrus | -3.03 | 0.0024 |
L. inferior temporal gyrus and R. inferior frontal gyrus | -2.97 | 0.003 |
L. precentral gyrus and R. superior temporal gyrus | -2.97 | 0.0031 |
L. inferior frontal gyrus and R. superior temporal gyrus | -2.91 | 0.0046 |
L. inferior frontal gyrus and R. inferior frontal gyrus | -2.84 | 0.0047 |
L. lateral orbitofrontal gyrus and R. superior temporal gyrus | -2.83 | 0.0047 |
Regions with higher coherence in ASD | ||
R. angular gyrus and R. fusiform gyrus | 4.38 | <0.0001 |
L. angular gyrus and R. angular gyrus | 4.13 | <0.0001 |
L. superior occipital gyrus and R. angular gyrus | 3.92 | 0.0001 |
R. angular gyrus and R. cuneus | 3.91 | 0.0001 |
R. fusiform gyrus and R. supramarginal gyrus | 3.87 | 0.0002 |
L. middle occipital gyrus and R. angular gyrus | 3.8 | 0.0001 |
L. superior parietal gyrus and R. fusiform gyrus | 3.71 | 0.0003 |
R. angular gyrus and R. inferior temporal gyrus | 3.67 | 0.0002 |
L. lingual gyrus and R. angular gyrus | 3.61 | 0.0003 |
R. fusiform gyrus and R. middle occipital gyrus | 3.59 | 0.0004 |
R. angular gyrus and R. middle occipital gyrus | 3.54 | 0.0004 |
R. angular gyrus and R. lingual gyrus | 3.49 | 0.0006 |
L. middle occipital gyrus and R. middle occipital gyrus | 3.44 | 0.0007 |
L. inferior occipital gyrus and R. angular gyrus | 3.39 | 0.0007 |
L. angular gyrus and R. middle occipital gyrus | 3.38 | 0.0007 |
L. superior occipital gyrus and R. supramarginal gyrus | 3.36 | 0.0008 |
R. fusiform gyrus and R. gyrus rectus | 3.34 | 0.0014 |
L. angular gyrus and L. superior temporal gyrus | 3.32 | 0.0009 |
L. angular gyrus and R. fusiform gyrus | 3.32 | 0.001 |
R. cuneus and R. supramarginal gyrus | 3.29 | 0.001 |
R. angular gyrus and R. inferior occipital gyrus | 3.28 | 0.001 |
L. angular gyrus and R. supramarginal gyrus | 3.25 | 0.0014 |
L. superior occipital gyrus and R. superior frontal gyrus | 3.14 | 0.0017 |
R. inferior temporal gyrus and R. middle occipital gyrus | 3.14 | 0.0018 |
L. angular gyrus and R. inferior temporal gyrus | 3.12 | 0.0018 |
R. angular gyrus and R. middle orbitofrontal gyrus | 3.1 | 0.002 |
L. gyrus rectus and L. superior occipital gyrus | 3.1 | 0.0031 |
L. angular gyrus and L. lateral orbitofrontal gyrus | 3.06 | 0.0022 |
L. superior parietal gyrus and R. inferior temporal gyrus | 3.04 | 0.0024 |
L. superior occipital gyrus and R. middle occipital gyrus | 2.99 | 0.0032 |
R. angular gyrus and R. lateral orbitofrontal gyrus | 2.98 | 0.0028 |
L. superior occipital gyrus and R. lateral orbitofrontal gyrus | 2.98 | 0.003 |
L. middle occipital gyrus and R. fusiform gyrus | 2.93 | 0.0034 |
R. gyrus rectus and R. inferior temporal gyrus | 2.93 | 0.0042 |
L. angular gyrus and L. middle occipital gyrus | 2.91 | 0.0037 |
L. inferior occipital gyrus and R. fusiform gyrus | 2.9 | 0.0038 |
L. fusiform gyrus and R. angular gyrus | 2.9 | 0.0046 |
L. angular gyrus and R. lateral orbitofrontal gyrus | 2.85 | 0.0044 |
Relationship between oscillatory activity and clinical symptomatology
Averted gaze | Direct gaze | ||||||
---|---|---|---|---|---|---|---|
0 to 15 Hz | τ | 15 to 30 Hz | τ | 30 to 45 Hz | τ | Collapsed across all frequencies | τ |
L. angular gyrus and L. lingual gyrus | 0.55*** | L. lateral orbitofrontal gyrus and R. postcentral gyrus | -0.53** | L. angular gyrus and R. lateral orbitofrontal gyrus | -0.55*** | L. angular gyrus and L. supramarginal gyrus | 0.46*** |
L. angular gyrus and L. middle temporal gyrus | 0.56*** | L. middle frontal gyrus and R precentral gyrus | -0.60*** | L. inferior frontal gyrus and R. precentral gyrus | -0.66**** | L. inferior frontal gyrus and R. precentral gyrus | -0.41** |
L. angular gyrus and L. superior temporal gyrus | 0.60*** | L superior occipital gyrus and R. inferior occipital gyrus | -0.52** | L. inferior occipital gyrus and R. fusiform gyrus | 0.57*** | L. lateral orbitofrontal gyrus and R. precentral gyrus | -0.44*** |
L. angular gyrus and R. angular gyrus | 0.54*** | R. inferior frontal gyrus and R. middle frontal gyrus | -0.51** | L. inferior temporal gyrus and R. precentral gyrus | -0.59*** | ||
L. angular gyrus and R. middle temporal gyrus | 0.50** | R. inferior frontal gyrus and R. superior frontal gyrus | -0.63**** | L. lateral orbitofrontal gyrus and R. precentral gyrus | -0.57*** | ||
L. inferior frontal gyrus and R. middle frontal gyrus | -0.56*** | R. middle orbitofrontal gyrus and R. precentral gyrus | 0.59*** | L. lingual gyrus and R. angular gyrus | 0.57*** | ||
L. inferior temporal gyrus and R. cuneus | 0.66**** | R. superior frontal gyrus and R. superior temporal gyrus | -0.52** | L. middle frontal gyrus and R. precentral gyrus | -0.53** | ||
L. middle occipital gyrus and L. middle temporal gyrus | 0.52** | L. middle occipital gyrus and R. fusiform gyrus | 0.51** | ||||
R. angular gyrus and R. superior frontal gyrus | -0.56*** | L. precentral gyrus and R. superior temporal gyrus | -0.50** | ||||
R cuneus and R. gyrus rectus | -0.59*** | L. superior frontal gyrus and R. superior temporal gyrus | -0.50** | ||||
R middle frontal gyrus and R superior frontal gyrus | -0.74**** | L. superior occipital gyrus and R. lateral orbitofrontal gyrus | -0.60*** | ||||
R. angular gyrus and R. cuneus | 0.64**** | ||||||
R. angular gyrus and R. fusiform gyrus | 0.62*** | ||||||
R. angular gyrus and R. inferior occipital gyrus | 0.51** | ||||||
R. angular gyrus and R. inferior temporal gyrus | 0.53** | ||||||
R. angular gyrus and R. lingual gyrus | 0.64**** | ||||||
R. angular gyrus and R. middle occipital gyrus | 0.71**** | ||||||
R. angular gyrus and R. middle orbitofrontal gyrus | 0.56*** | ||||||
R. fusiform gyrus and R. middle occipital gyrus | 0.61*** | ||||||
R. inferior temporal gyrus and R. middle occipital gyrus | 0.53** |