Neuroendocrine responses to traumatic brain injury

Excerpt

Traumatic brain injury (TBI) is a serious public health problem worldwide associated with increased mortality and disability especially among young people. Pituitary dysfunction was described for the first time a century ago occurring as a consequence of TBI [1]. Until 20 years ago, post-traumatic pituitary dysfunction received little attention, and during the following years, increasing numbers of papers were published in the literature. A special issue of Pituitary was devoted to TBI-induced hypopituitarism in 2005. Studies of neuroendocrine changes and brain injury have expanded the frontiers of endocrinology. The increasing amount of new data has required this current special issue on TBI-induced neuroendocrine changes. Scientists and clinicians from a variety of disciplines including endocrinology, neurology, pathology, immunology, stem cell, developmental biology and neurosurgery kindly contributed to this special issue of Pituitary.

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