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NeuroMolecular Medicine

NeuroMolecular Medicine OnlineFirst articles

18.11.2020 | Original Paper

Molecular Classification of Gliomas is Associated with Seizure Control: A Retrospective Analysis

Classically, histologic grading of gliomas has been used to predict seizure association, with low-grade gliomas associated with an increased incidence of seizures compared to high-grade gliomas. In 2016, WHO reclassified gliomas based on histology …

18.11.2020 | Mini-reviews Open Access

The Gut Ecosystem: A Critical Player in Stroke

The intestinal microbiome is emerging as a critical factor in health and disease. The microbes, although spatially restricted to the gut, are communicating and modulating the function of distant organs such as the brain. Stroke and other …

18.11.2020 | Review Paper Open Access

Recent Insights on the Role of PPAR-β/δ in Neuroinflammation and Neurodegeneration, and Its Potential Target for Therapy

Peroxisome proliferator-activated receptor (PPAR) β/δ belongs to the family of hormone and lipid-activated nuclear receptors, which are involved in metabolism of long-chain fatty acids, cholesterol, and sphingolipids. Similar to PPAR-α and PPAR-γ …

13.11.2020 | Original Paper

Remote Ischemic Post-Conditioning Therapy is Protective in Mouse Model of Traumatic Optic Neuropathy

Traumatic optic neuropathy (TON) is characterized by visual dysfunction after indirect or direct injury to the optic nerve following blunt head trauma. TON is associated with increased oxidative stress and inflammation resulting in retinal …

12.11.2020 | Review Paper

Preclinical and Clinical Evidence for the Involvement of Sphingosine 1-Phosphate Signaling in the Pathophysiology of Vascular Cognitive Impairment

Sphingosine 1-phosphates (S1Ps) are bioactive lipids that mediate a diverse range of effects through the activation of cognate receptors, S1P1–S1P5. Scrutiny of S1P-regulated pathways over the past three decades has identified important and …

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NeuroMolecular Medicine presents cutting-edge research articles and critical reviews on the molecular and biochemical basis of neurological disorders. Coverage ranges from genetic analyses of human populations to animal and cell culture models of neurological disorders, and includes findings concerning the identification of genetic aberrancies and their pathogenic mechanisms at the molecular and cellular levels. Coverage includes experimental analyses of molecular cascades involved in the development and adult plasticity of the nervous system, in neurological dysfunction, and in neuronal degeneration and repair. NeuroMolecular Medicine encompasses basic research in molecular genetics, signal transduction, plasticity, and cell death. The journal gives special attention to synthetic research and reviews that aim to bridge genetic aberrancies with cellular and molecular mechanisms of neurological pathogenesis.

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Neu in den Fachgebieten Neurologie und Psychiatrie