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Canadian Journal of Anesthesia/Journal canadien d'anesthésie

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28.07.2016 | Editorials

Newer isn’t always better: comparative effectiveness of sevoflurane and isoflurane in cardiac surgery

verfasst von: Michael R. Mathis, MD, Sachin Kheterpal, MD, MBA

Erschienen in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Ausgabe 10/2016

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Excerpt

In this issue of the Journal, Jones et al. 1 present a comparative effectiveness trial showing no difference in clinically relevant outcomes between sevoflurane and isoflurane when used for anesthetic maintenance during cardiac surgery. Specifically, the authors showed that sevoflurane is non-inferior to isoflurane based on a primary outcome composite measure of prolonged intensive care unit (ICU) length of stay (LOS) and all-cause 30-day mortality. Furthermore, the authors found that sevoflurane is not superior to isoflurane on any other clinically important outcome. …

Jones PM. Bainbridge D, Chu MW, et al. Comparison of isoflurane and sevoflurane in cardiac surgery: a randomized non-inferiority comparative effectiveness trial. Can J Anesth 2016; 63: this issue. DOI: 10.1007/s12630-016-0706-y

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Titel: Newer isn’t always better: comparative effectiveness of sevoflurane and isoflurane in cardiac surgery
verfasst von: Michael R. Mathis, MD
Sachin Kheterpal, MD, MBA
Publikationsdatum: 28.07.2016
Verlag: Springer US
Erschienen in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Ausgabe 10/2016
Print ISSN: 0832-610X
Elektronische ISSN: 1496-8975
DOI: https://doi.org/10.1007/s12630-016-0705-z

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Newer isn’t always better: comparative effectiveness of sevoflurane and isoflurane in cardiac surgery

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