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Irish Journal of Medical Science (1971 -)

Erschienen in:

01.09.2010 | Original Article

Non-steroidal anti-inflammatory drug prescriptions in hospital inpatients: are we assessing the risks?

verfasst von: J. Kitchen, D. Kane

Erschienen in: Irish Journal of Medical Science (1971 -) | Ausgabe 3/2010

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Abstract

Aim

To determine non-steroidal anti-inflammatory drug (NSAID) prescribing practices in a tertiary referral hospital.

Methods

A single time-point audit of drug kardexes and clinical notes of n = 388 patients on 2 July 2008 was carried out assessing demographics, gastrointestinal and coronary heart disease risk factors, renal function and co-prescribed medications.

Results

Fifty-seven of 388 (14.7%) hospital patients were on NSAIDs. Forty-nine were prescribed NSAID after admission. Nineteen (32.2%) were on regular NSAID (11/19 on PPI) and 38 patients were on PRN NSAID (12/38 on PPI). Seventeen of 49 patients were on other medications associated with gastrointestinal bleeding (10/17 were on PPI). Nineteen patients (33.3%) were >60 years. Eight patients had three or four risk factors for gastrointestinal bleeding; six were on PPI. Thirteen patients had two risks; 7 were on PPI. Six of 19 patients with one risk factor were on PPI. 40.3% had stage 2/3 chronic kidney disease. 35.1% had ischaemic heart disease.

Conclusions

NSAIDs and PPIs are often prescribed inappropriately.

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Titel: Non-steroidal anti-inflammatory drug prescriptions in hospital inpatients: are we assessing the risks?
verfasst von: J. Kitchen
D. Kane
Publikationsdatum: 01.09.2010
Verlag: Springer-Verlag
Erschienen in: Irish Journal of Medical Science (1971 -) / Ausgabe 3/2010
Print ISSN: 0021-1265
Elektronische ISSN: 1863-4362
DOI: https://doi.org/10.1007/s11845-010-0496-0

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Non-steroidal anti-inflammatory drug prescriptions in hospital inpatients: are we assessing the risks?

Abstract