Erschienen in:
18.05.2019 | Introduction to Invited Review Articles
Novel therapeutic strategy based on genetic and epigenetic abnormalities for myeloid neoplasms
verfasst von:
Takahiro Yamauchi
Erschienen in:
International Journal of Clinical Oncology
|
Ausgabe 8/2019
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Excerpt
Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDSs) are representative diseases of myeloid neoplasms [
1]. There are some similarities of the molecular pathogenesis between AML and MDS, but it is not entirely identical [
1‐
3]. Genetic and epigenetic abnormalities are crucial to the understanding their pathogenesis, and are also the bases of the development of new therapeutic agents. …