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Erschienen in:
01.06.2009 | Review
Oral manifestations of HIV/AIDS in China: a review
Erschienen in: Oral and Maxillofacial Surgery | Ausgabe 2/2009
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Purpose
The purpose of this study is to review the Chinese-language medical and dental literature from 1982 to 2008 on oral manifestations (OMs) of patients with HIV/AIDS for introducing the spectrum of OMs of the patients in China.
Materials and methods
All data were extracted from 18 references which had used diagnostic criteria for HIV/AIDS. Four of the references had used the EC-Clearinghouse classification for oral lesions in HIV infection. The feasible overall rate and 95% confidence interval (95%CI) of the data on OMs were calculated.
Results
Risk group analysis revealed that, of 203 patients, 64.3% were men and 35.7% were women (age range, 5 months to 64 years; mean age in three studies, 34.0, 34.3, and 36.1 years). Of these patients, 22.2% were infected by sexual contacts, 11.8% by intravenous drug use (IDU), 59.6% by blood or its products, 2.9% by mother to child transmission, and 3.4% were unclear. In 203 patients, oral candidiasis (OC) was the most common lesion (66%, 95%CI = 59.48–72.52%), followed by herpes simplex (HS) (22.2%, 95%CI = 16.48–27.92%), ulcerative stomatitis (14.8%, 95%CI = 9.92–19.68%), salivary gland disease (11.3%, 95%CI = 6.94–15.66%), oral hairy leukoplakia (OHL) (9.8%, 95%CI = 5.71–13.89%), necrotizing gingivitis (5.9%, 95%CI = 2.66–9.14%), Kaposi’s sarcoma (2.9%, 95%CI = 0.59–5.21%), other malignant tumors (2.9%, 95%CI = 0.59–5.21%), and linear gingival erythema (2.0%, 95%CI = 0.07–3.93%).
Conclusions
The spectrum of OMs reported from China is similar to that described in the international literature. Present data are useful to supplement international resources of HIV/AIDS research.