Skip to main content
main-content

01.12.2015 | Case report | Ausgabe 1/2015 Open Access

BMC Oral Health 1/2015

Osteolysis of unknown origin: a case report

Zeitschrift:
BMC Oral Health > Ausgabe 1/2015
Autoren:
Matthias Guido Wiesli, Katrin E. Hostettler, Michael Tamm, Claude Jaquiéry
Wichtige Hinweise

Competing interests

The authors declare that they have no competing interests.

Authors’ contribution

Conception and design of study: MGW, KH, CJ. Acquisition, analysis or interpretation of data: MGW, KH, CJ. Drafting of the manuscript: MGW, KH. Revising of the manuscript: CJ, MT. All authors approved the version submitted for publication.

Abstract

Background

Sarcoidosis is a granulomatous disease that may affect any organ of the body. The most frequent loci of manifestation are the lungs. However, there are individual cases where bones are affected. The literature describes cases in which swelling or fistula were the first findings of a bone lesion. This is the first case reporting an osteolysis in both angles of the mandibles which led to the diagnosis of sarcoidosis with multi-organ involvement.

Case presentation

The authors present a 74 years old European female patient without previous diagnosis of sarcoidosis who presented with pain in the area of the jaw angles. There were no further clinical symptoms. Bone biopsy following radiological investigation demonstrated non-caseating granulomas consistent with sarcoidosis of the bone. Further evaluation confirmed multi-organ disease with involvement of lungs, intrathoracic lymph nodes, and the central nervous system.

Conclusion

This case report shows that diagnosis of a severe disease can be missed if systematic clinical signs are not given. Furthermore, an accurate anamnesis and examination is required to receive an early diagnosis which often needs an interdisciplinary approach.
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2015

BMC Oral Health 1/2015 Zur Ausgabe

Neu im Fachgebiet Zahnmedizin

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Zahnmedizin und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise