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Drugs & Aging
Erschienen in: Drugs & Aging 8/2020

19.06.2020 | Current Opinion

Overactive Bladder in Frail Older Adults

verfasst von: Christina Shaw, Adrian Wagg

Erschienen in: Drugs & Aging | Ausgabe 8/2020

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Abstract

Overactive bladder (OAB) and frailty are multidimensional syndromes, and the prevalence of both increases with age. Little evidence exists for a direct association between OAB and frailty, but urinary urgency may well be a precursor of frailty in older people. Frail older adults are no less deserving of treatment than fit older adults, and lifestyle, behavioral, and pharmacological interventions remain the primary options for treatment, with some evidence for efficacy. Data on onabotulinumtoxinA therapy or percutaneous tibial nerve stimulation in frail older adults are sparse. Frail older adults are often excluded from drug trials, but evidence is accumulating that antimuscarinics and, to a lesser extent, beta-adrenergic agonists are safe, well-tolerated, and effective in older adults. Cognitive impairment associated with frailty should not be used as justification for avoiding the use of antimuscarinics. More studies are required to better understand the association between OAB and frailty, as both are associated with poor outcomes and may be amenable to intervention. Drug trials for OAB treatments should be encouraged to include frail older adults, as this population is highly affected yet often excluded.
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Metadaten
Titel
Overactive Bladder in Frail Older Adults
verfasst von
Christina Shaw
Adrian Wagg
Publikationsdatum
19.06.2020
Verlag
Springer International Publishing
Erschienen in
Drugs & Aging / Ausgabe 8/2020
Print ISSN: 1170-229X
Elektronische ISSN: 1179-1969
DOI
https://doi.org/10.1007/s40266-020-00777-8

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