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Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases 3/2017

03.11.2016 | Original Article

Paediatric antibiotic prescriptions in primary care in the Alpes-Maritimes area of southeastern France between 2008 and 2013

verfasst von: P. Touboul-Lundgren, P. Bruno, L. Bailly, B. Dunais, C. Pradier

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 3/2017

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Abstract

France has remained among the top five European countries for ambulatory antibiotic consumption since such monitoring began in 1998. Young children are major antibiotic consumers, in spite of the viral origin of most infections in this population. Recommendations were updated in 2011 to limit prescriptions. In order to assess their impact, diagnoses and prescriptions were compared in a population of children attending daycare centres in southeastern France in 2008 and 2012. Trends in the reimbursement of paediatric antibiotic prescriptions by the national health insurance (NHI) for the whole area were also studied. Distribution of diagnoses accounting for antibiotic treatment and type of antibiotic prescribed over the previous 3 months to children below 4 years of age attending daycare centres in the Alpes-Maritimes area in southeastern France were compared between 2008 and 2012 prior to and following the availability of these new recommendations. Trends in reimbursed ambulatory antibiotic prescriptions by general practitioners and paediatricians in the area were studied for this age group from 2008 to 2012 and in 2013. The majority of recorded diagnoses concerned upper respiratory tract infections (URTI). Inappropriate antibiotic prescription persisted for colds and bronchitis in similar proportions during both surveys. Improvement in the choice of antibiotic with fewer prescriptions for third-generation cephalosporins was observed both in daycare centres and according to NHI data; however, this was mainly recorded among paediatricians. The management of paediatric URTI still needs improvement, pointing to the need to investigate and adequately address the reasons for inappropriate antibiotic prescription.
Literatur
1.
Zurück zum Zitat Nyquist AC, Gonzales R, Steiner JF, Sande MA (1998) Antibiotic prescribing for children with colds, upper respiratory tract infections, and bronchitis. JAMA 279(11):875–877CrossRefPubMed Nyquist AC, Gonzales R, Steiner JF, Sande MA (1998) Antibiotic prescribing for children with colds, upper respiratory tract infections, and bronchitis. JAMA 279(11):875–877CrossRefPubMed
2.
Zurück zum Zitat Touboul-Lundgren P, Jensen S, Drai J, Lindbæk M (2015) Identification of cultural determinants of antibiotic use cited in primary care in Europe: a mixed research synthesis study of integrated design “Culture is all around us”. BMC Public Health 15(1):908. doi:10.1186/s12889-015-2254-8 CrossRefPubMedPubMedCentral Touboul-Lundgren P, Jensen S, Drai J, Lindbæk M (2015) Identification of cultural determinants of antibiotic use cited in primary care in Europe: a mixed research synthesis study of integrated design “Culture is all around us”. BMC Public Health 15(1):908. doi:10.​1186/​s12889-015-2254-8 CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Elseviers MM, Ferech M, Vander Stichele RH, Goossens H; ESAC project group (2007) Antibiotic use in ambulatory care in Europe (ESAC data 1997–2002): trends, regional differences and seasonal fluctuations. Pharmacoepidemiol Drug Saf 16(1):115–123CrossRefPubMed Elseviers MM, Ferech M, Vander Stichele RH, Goossens H; ESAC project group (2007) Antibiotic use in ambulatory care in Europe (ESAC data 1997–2002): trends, regional differences and seasonal fluctuations. Pharmacoepidemiol Drug Saf 16(1):115–123CrossRefPubMed
5.
6.
Zurück zum Zitat Dunais B, Bruno P, Touboul P, Degand N, Sakarovitch C, Fontas E, Haas H, Girard-Pipau F, Ruimy R, Pradier C (2015) Impact of the 13-valent pneumococcal conjugate vaccine on nasopharyngeal carriage of Streptococcus pneumoniae among children attending group daycare in southeastern France. Pediatr Infect Dis J 34(3):286–288. doi:10.1097/INF.0000000000000559 CrossRefPubMed Dunais B, Bruno P, Touboul P, Degand N, Sakarovitch C, Fontas E, Haas H, Girard-Pipau F, Ruimy R, Pradier C (2015) Impact of the 13-valent pneumococcal conjugate vaccine on nasopharyngeal carriage of Streptococcus pneumoniae among children attending group daycare in southeastern France. Pediatr Infect Dis J 34(3):286–288. doi:10.​1097/​INF.​0000000000000559​ CrossRefPubMed
8.
Zurück zum Zitat Blanc V, Leflon-Guibout V, Blanco J, Haenni M, Madec JY, Rafignon G, Bruno P, Mora A, Lopez C, Dahbi G, Dunais B, Anastay M, Branger C, Moreau R, Pradier C, Nicolas-Chanoine MH (2014) Prevalence of day-care centre children (France) with faecal CTX-M-producing Escherichia coli comprising O25b:H4 and O16:H5 ST131 strains. J Antimicrob Chemother 69(5):1231–1237. doi:10.1093/jac/dkt519 CrossRefPubMed Blanc V, Leflon-Guibout V, Blanco J, Haenni M, Madec JY, Rafignon G, Bruno P, Mora A, Lopez C, Dahbi G, Dunais B, Anastay M, Branger C, Moreau R, Pradier C, Nicolas-Chanoine MH (2014) Prevalence of day-care centre children (France) with faecal CTX-M-producing Escherichia coli comprising O25b:H4 and O16:H5 ST131 strains. J Antimicrob Chemother 69(5):1231–1237. doi:10.​1093/​jac/​dkt519 CrossRefPubMed
9.
Zurück zum Zitat Koningstein M, Leenen MA, Mughini-Gras L, Scholts RM, van Huisstede-Vlaanderen KW, Enserink R, Zuidema R, Kooistra-Smid MA, Veldman K, Mevius D, van Pelt W (2015) Prevalence and risk factors for colonization with extended-spectrum cephalosporin-resistant Escherichia coli in children attending daycare centers: a cohort study in the Netherlands. J Pediatric Infect Dis Soc 4(4):e93–e99. doi:10.1093/jpids/piv042 PubMed Koningstein M, Leenen MA, Mughini-Gras L, Scholts RM, van Huisstede-Vlaanderen KW, Enserink R, Zuidema R, Kooistra-Smid MA, Veldman K, Mevius D, van Pelt W (2015) Prevalence and risk factors for colonization with extended-spectrum cephalosporin-resistant Escherichia coli in children attending daycare centers: a cohort study in the Netherlands. J Pediatric Infect Dis Soc 4(4):e93–e99. doi:10.​1093/​jpids/​piv042 PubMed
10.
Zurück zum Zitat Fan NC, Chen HH, Chen CL, Ou LS, Lin TY, Tsai MH, Chiu CH (2014) Rise of community-onset urinary tract infection caused by extended-spectrum β-lactamase-producing Escherichia coli in children. J Microbiol Immunol Infect 47(5):399–405. doi:10.1016/j.jmii.2013.05.006 CrossRefPubMed Fan NC, Chen HH, Chen CL, Ou LS, Lin TY, Tsai MH, Chiu CH (2014) Rise of community-onset urinary tract infection caused by extended-spectrum β-lactamase-producing Escherichia coli in children. J Microbiol Immunol Infect 47(5):399–405. doi:10.​1016/​j.​jmii.​2013.​05.​006 CrossRefPubMed
11.
Zurück zum Zitat Boutet-Dubois A, Pantel A, Prère MF, Bellon O, Brieu-Roche N, Lecaillon E, Le Coustumier A, Davin-Regli A, Villeneuve L, Bouziges N, Gleize E, Lamarca R, Dunyach-Remy C, Sotto A, Lavigne JP (2013) Faecal carriage of oxyiminocephalosporin-resistant Enterobacteriaceae among paediatric units in different hospitals in the south of France. Eur J Clin Microbiol Infect Dis 32(8):1063–1068. doi:10.1007/s10096-013-1851-7 CrossRefPubMed Boutet-Dubois A, Pantel A, Prère MF, Bellon O, Brieu-Roche N, Lecaillon E, Le Coustumier A, Davin-Regli A, Villeneuve L, Bouziges N, Gleize E, Lamarca R, Dunyach-Remy C, Sotto A, Lavigne JP (2013) Faecal carriage of oxyiminocephalosporin-resistant Enterobacteriaceae among paediatric units in different hospitals in the south of France. Eur J Clin Microbiol Infect Dis 32(8):1063–1068. doi:10.​1007/​s10096-013-1851-7 CrossRefPubMed
13.
14.
15.
Zurück zum Zitat Tell D, Engström S, Mölstad S (2015) Adherence to guidelines on antibiotic treatment for respiratory tract infections in various categories of physicians: a retrospective cross-sectional study of data from electronic patient records. BMJ Open 5(7):e008096. doi:10.1136/bmjopen-2015-008096, Jul 15CrossRefPubMedPubMedCentral Tell D, Engström S, Mölstad S (2015) Adherence to guidelines on antibiotic treatment for respiratory tract infections in various categories of physicians: a retrospective cross-sectional study of data from electronic patient records. BMJ Open 5(7):e008096. doi:10.​1136/​bmjopen-2015-008096, Jul 15CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat de Bont EG, Peetoom KK, Moser A, Francis NA, Dinant GJ, Cals JW (2015) Childhood fever: a qualitative study on GPs’ experiences during out-of-hours care. Fam Pract 32(4):449–455. doi:10.1093/fampra/cmv029 PubMed de Bont EG, Peetoom KK, Moser A, Francis NA, Dinant GJ, Cals JW (2015) Childhood fever: a qualitative study on GPs’ experiences during out-of-hours care. Fam Pract 32(4):449–455. doi:10.​1093/​fampra/​cmv029 PubMed
21.
Zurück zum Zitat Cabral C, Lucas PJ, Ingram J, Hay AD, Horwood J (2015) “It’s safer to …” parent consulting and clinician antibiotic prescribing decisions for children with respiratory tract infections: An analysis across four qualitative studies. Soc Sci Med 136–137:156–164. doi:10.1016/j.socscimed.2015.05.027 CrossRefPubMed Cabral C, Lucas PJ, Ingram J, Hay AD, Horwood J (2015) “It’s safer to …” parent consulting and clinician antibiotic prescribing decisions for children with respiratory tract infections: An analysis across four qualitative studies. Soc Sci Med 136–137:156–164. doi:10.​1016/​j.​socscimed.​2015.​05.​027 CrossRefPubMed
Metadaten
Titel
Paediatric antibiotic prescriptions in primary care in the Alpes-Maritimes area of southeastern France between 2008 and 2013
verfasst von
P. Touboul-Lundgren
P. Bruno
L. Bailly
B. Dunais
C. Pradier
Publikationsdatum
03.11.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 3/2017
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-016-2826-2

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