Introduction
Materials and methods
Subjects
Recruitment
Subject preparation and preparation of MRI facility prior to scan
Sound attenuation and reducing intra-scan motion
Pediatric imaging and imaging protocols
Age group (months) | 3–9 | 9–16 | 16–28 | 28–48 |
---|---|---|---|---|
Acquisition time (min:sec) | 18:22 | 18:42 | 21:38 | 24:20 |
Field of view (cm3) | 14 × 14 × 13 | 17 × 17 × 14.4 | 18 × 18 × 15 | 20 × 20 × 15 |
Unprotected dBa
| 54 | 62 | 69 | 74 |
SPGR TR/TE (ms) | 12/5.8 | 12/5.9 | 12/5.4 | 11/5.2 |
SPGR flip angles (degrees) | 2, 3, 4, 5, 7, 9, 11, 14 | 2, 3, 4, 5, 7, 9, 11, 14 | 2, 3, 4, 5, 7, 9, 11, 14 | 2, 3, 4, 5, 7, 9, 12, 16 |
IR-SPGR inversion time (ms) | 600/950 | 600/900 | 500/850 | 500/800 |
bSSFP TR/TE (ms) | 10/5 | 10.2/5.1 | 10/5 | 9.8/4.4 |
bSSFP flip angles (degrees) | 9, 14, 20, 27, 34, 41, 56, 70 | 9, 14, 20, 27, 34, 41, 56, 70 | 9, 14, 20, 27, 34, 41, 56, 70 | 9, 14, 20, 27, 34, 41, 56, 70 |
Longitudinal MRI scans
Results
Characteristics | Males (129) | Females (91) |
---|---|---|
Gestational corrected age (initial scan, days) | 594.4 ± 455.1 | 519.9 ± 429.5 |
Gestation duration (weeks) | 39.5 ± 1.2 | 39.5 ± 1.3 |
Ethnicity (Hispanic/non-Hispanic/not reported) | 25/82/22 | 15/67/9 |
Race (African American/Asian/Caucasian/mixed race/unknown or not reported) | 11/1/74/20/23 | 7/2/61/10/11 |
Longitudinal imaging
Age group | Gender | Initial scans | Follow-up #1 scans | Follow-up #2 scans | Follow-up #3 scans |
---|---|---|---|---|---|
3–24 months | Male | 81 | 44 | 19 | 4 |
3–24 months | Female | 67 | 39 | 14 | 6 |
24–48 months | Male | 48 | 20 | 7 | 0 |
24–48 months | Female | 24 | 9 | 2 | 0 |