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Journal of Neural Transmission

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01.10.2011 | Movement Disorders - Original Article

Pedunculopontine stimulation from primate to patient

verfasst von: Erlick A. C. Pereira, Dipankar Nandi, Ned Jenkinson, John F. Stein, Alexander L. Green, Tipu Z. Aziz

Erschienen in: Journal of Neural Transmission | Ausgabe 10/2011

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Abstract

Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a novel neurosurgical therapy developed to address symptoms of gait freezing and postural instability in Parkinson’s disease and related disorders. Here we summarise our non-human primate investigations of relevance to our surgical targeting of the PPN and relate the primate research to initial clinical experience of PPN DBS.

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Titel: Pedunculopontine stimulation from primate to patient
verfasst von: Erlick A. C. Pereira
Dipankar Nandi
Ned Jenkinson
John F. Stein
Alexander L. Green
Tipu Z. Aziz
Publikationsdatum: 01.10.2011
Verlag: Springer Vienna
Erschienen in: Journal of Neural Transmission / Ausgabe 10/2011
Print ISSN: 0300-9564
Elektronische ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-011-0631-8

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