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Journal of Neural Transmission

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01.10.2011 | Basic Neurosciences, Genetics and Immunology - Review Article

The pedunculopontine nucleus as a target for deep brain stimulation

verfasst von: Clement Hamani, Elena Moro, Andres M. Lozano

Erschienen in: Journal of Neural Transmission | Ausgabe 10/2011

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Abstract

The pedunculopontine nucleus (PPN) is a brain stem locomotive center that is also involved in the processing of sensory and behavioral information. The PPN has been recently proposed as a potential target for the treatment of axial symptoms in Parkinson’s disease (PD). To date, results of the first series of PD patients treated with PPN deep brain stimulation (DBS) have shown promising results. In this article, we review some of the basic aspects of the PPN as a target and the outcome of the recently published clinical trials.

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Titel: The pedunculopontine nucleus as a target for deep brain stimulation
verfasst von: Clement Hamani
Elena Moro
Andres M. Lozano
Publikationsdatum: 01.10.2011
Verlag: Springer Vienna
Erschienen in: Journal of Neural Transmission / Ausgabe 10/2011
Print ISSN: 0300-9564
Elektronische ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-010-0547-8

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