Erschienen in:
01.05.2008 | Case Report
Pelvic Cancer Ten Years after Restorative Proctocolectomy in Indeterminate Colitis: Report of a Case
verfasst von:
David Stern, M.D., Dipen Maun, M.D., Stephen R. Gorfine, M.D., Joel J. Bauer, M.D.
Erschienen in:
Diseases of the Colon & Rectum
|
Ausgabe 5/2008
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Excerpt
Restorative proctocolectomy is generally accepted as the procedure of choice for patients with chronic ulcerative colitis requiring surgery. Restorative proctocolectomy for patients with indeterminate colitis is somewhat more controversial because the reported complication rate is higher after this procedure.
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4 For either diagnosis, most surgeons believe that restorative proctocolectomy greatly reduces or even eliminates the risk of inflammatory bowel disease-associated colorectal cancer. Although restorative proctocolectomy does seem to lower the cancer risk, it is not eliminated. Eighteen cases of postoperative “pouch-related” cancers after restorative proctocolectomy have been reported in the literature.
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22 Most of these cancers were discovered fairly soon after restorative proctocolectomy, and all but two were found in patients with chronic ulcerative colitis. There have been no reports of pouch-related cancer in patients with indeterminate colitis. We present a patient with indeterminate colitis who developed pouch-related adenocarcinoma ten years after restorative proctocolectomy despite on-going pouch surveillance. …