nach oben

Erschienen in:

24.12.2022 | Original Article

Physical and nonphysical effects of weekly music therapy intervention on the condition of radiooncology patients

verfasst von: Patrick Clemens, Philipp Szeverinski, Peter Tschann, Marion Dietl, Joyce Gurk, Matthias Kowatsch, Gerhard Tucek, Alexander de Vries

Erschienen in: Strahlentherapie und Onkologie | Ausgabe 3/2023

Einloggen, um Zugang zu erhalten

Abstract

Purpose

In oncology settings, music, especially music therapy (MT), is frequently used to improve patients’ quality of life, pain situation, anxiety, depression, fatigue, and comfort. However, to date, there are no prospectively collected data correlating regular standardized MT sessions during radiotherapy (RT) to physical parameters such as heart rate, blood pressure, respiratory rate, and oxygen saturation and corresponding quality of life measures using quantitative descriptive scales in oncological patients. Thus, the aim of this study was to investigate the effect of MT on the condition of radiooncology patients using these parameters.

Materials and methods

During this study, patients participated weekly MT sessions guided by a board-certified music therapist. Data such as pain, physical comfort, and respiratory comfort based on the visual analogue scale (VAS) were collected before and after MT sessions. Furthermore, vital signs including heart rate, blood pressure, respiratory rate, and oxygen saturation as well as RT side effects were recorded.

Results

A total of 57 patients (age 61 ± 11 years) were enrolled in the study. Median VAS score was significantly different before and after MT for pain: VAS 1 (interquartile range [IQR]: 0–3) vs. VAS 0 (IQR: 0–2; p < 0.001); physical comfort: VAS 7 (IQR: 6–7) vs. VAS 8 (IQR: 7–9; p < 0.001); and respiratory comfort only in the patients with pre-existing symptoms (VAS < 10 before therapy): VAS 8 (IQR: 6–8) vs. VAS 9 (IQR: 8–10; p = 0.002). Furthermore, vital signs were significantly reduced from pre-session to post-session (p > 0.001): heart rate 81 ± 14 min⁻¹ to 76 ± 13 min⁻¹ and respiratory rate from 12 ± 5 min⁻¹ to 10 ± 4 min⁻¹. RT-related side effects did not interfere with participation in MT sessions.

Conclusion

In our study cohort of radiooncology patients, weekly MT sessions improved defined physical parameters as well as pain, physical comfort, and respiratory comfort. Establishing MT in the routine clinical setting should be more readily considered to further improve patient outcomes.

McConnell T, Graham-Wisener L, Regan J et al (2016) Evaluation of the effectiveness of music therapy in improving the quality of life of palliative care patients: a randomised controlled pilot and feasibility study. Pilot Feasibility Stud 2:70. https://doi.org/10.1186/s40814-016-0111-xCrossRefPubMedPubMedCentral

Preissler P, Kordovan S, Ullrich A et al (2016) Favored subjects and psychosocial needs in music therapy in terminally ill cancer patients: a content analysis. BMC Palliat Care 15:48. https://doi.org/10.1186/s12904-016-0122-7CrossRefPubMedPubMedCentral

Demmer C (2004) A survey of complementary therapy services provided by hospices. J Palliat Med 7:510–516. https://doi.org/10.1089/jpm.2004.7.510CrossRefPubMed

Hilliard RE (2003) The effects of music therapy on the quality and length of life of people diagnosed with terminal cancer. J Music Ther 40:113–137CrossRefPubMed

Bradt J, Dileo C, Magill L, Teague A (2016) Music interventions for improving psychological and physical outcomes in cancer patients. Cochrane Database Syst Rev 8:CD6911. https://doi.org/10.1002/14651858.CD006911.pub3CrossRef

Horne-Thompson A, Grocke D (2008) The effect of music therapy on anxiety in patients who are terminally ill. J Palliat Med 11:582–590. https://doi.org/10.1089/jpm.2007.0193CrossRefPubMed

Greenlee H, DuPont-Reyes MJ, Balneaves LG et al (2017) Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment. CA Cancer J Clin 67:194–232. https://doi.org/10.3322/caac.21397CrossRefPubMedPubMedCentral

Bradt J, Dileo C, Myers-Coffman K, Biondo J (2021) Music interventions for improving psychological and physical outcomes in people with cancer. Cochrane Database Syst Rev 10:CD6911. https://doi.org/10.1002/14651858.CD006911.pub4CrossRefPubMed

Rossetti A, Loewy JV (2021) The music ‘question’ in research and practice. Int J Radiat Oncol Biol Phys 109:675–677. https://doi.org/10.1016/j.ijrobp.2020.11.025CrossRefPubMed

10.

Wheeler BL, Lesiuk TL, Burns DS et al (2019) Music therapy and music medicine studies in oncology: part I: a comparison. Music Med 11:145–159. https://doi.org/10.47513/mmd.v11i3.671CrossRef

11.

Bailey LM (1983) The effects of live music versus tape-recorded music on hospitalized cancer patients. Music Ther 3:17–28. https://doi.org/10.1093/mt/3.1.17CrossRef

12.

Dileo C (2006) Effects of music and music therapy on medical patients: a meta-analysis of the research and implications for the future. J Soc Integr Oncol 4:67–70. https://doi.org/10.2310/7200.2006.002CrossRefPubMed

13.

Stanczyk MM (2011) Music therapy in supportive cancer care. Rep Pract Oncol Radiother 16:170–172. https://doi.org/10.1016/j.rpor.2011.04.005CrossRefPubMedPubMedCentral

14.

Carlson LE, Waller A, Groff SL et al (2013) What goes up does not always come down: patterns of distress, physical and psychosocial morbidity in people with cancer over a one year period. Psychooncology 22:168–176. https://doi.org/10.1002/pon.2068CrossRefPubMed

15.

Okuyama T, Kizawa Y, Morita T et al (2016) Current status of distress screening in designated cancer hospitals: a cross-sectional nationwide survey in Japan. J Natl Compr Canc Netw 14:1098–1104. https://doi.org/10.6004/jnccn.2016.0119CrossRefPubMed

16.

Yang Y‑L, Liu L, Wang Y et al (2013) The prevalence of depression and anxiety among Chinese adults with cancer: a systematic review and meta-analysis. BMC Cancer 13:393. https://doi.org/10.1186/1471-2407-13-393CrossRefPubMedPubMedCentral

17.

Meggiolaro E, Berardi MA, Andritsch E et al (2016) Cancer patients’ emotional distress, coping styles and perception of doctor-patient interaction in European cancer settings. Palliat Support Care 14:204–211. https://doi.org/10.1017/S1478951515000760CrossRefPubMed

18.

Stiegelis HE, Ranchor AV, Sanderman R (2004) Psychological functioning in cancer patients treated with radiotherapy. Patient Educ Couns 52:131–141. https://doi.org/10.1016/s0738-3991(03)00021-1CrossRefPubMed

19.

Piroth MD, Draia S, Jawad JA, Piefke M (2022) Anxiety and depression in patients with breast cancer undergoing radiotherapy: the role of intelligence, life history, and social support—preliminary results from a monocentric analysis. Strahlenther Onkol. https://doi.org/10.1007/s00066-022-01904-7CrossRefPubMedPubMedCentral

20.

Voigtmann K, Köllner V, Einsle F et al (2010) Emotional state of patients in radiotherapy and how they deal with their disorder. Strahlenther Onkol 186:229–235. https://doi.org/10.1007/s00066-010-2109-2CrossRefPubMed

21.

Janda M, Newman B, Obermair A et al (2004) Impaired quality of life in patients commencing radiotherapy for cancer. Strahlenther Onkol 180:78–83. https://doi.org/10.1007/s00066-004-1160-2CrossRefPubMed

22.

Körner P, Ehrmann K, Hartmannsgruber J et al (2017) Patient-reported symptoms during radiotherapy. Strahlenther Onkol 193:570–577. https://doi.org/10.1007/s00066-017-1146-5CrossRefPubMed

23.

Sehlen S, Hollenhorst H, Schymura B et al (2003) Psychosocial stress in cancer patients during and after radiotherapy. Strahlenther Onkol 179:175–180. https://doi.org/10.1007/s00066-003-1018-zCrossRefPubMed

24.

de Vries A, Söllner W, Steixner E et al (1998) Subjektiv erlebte Belastung und Bedarf an psychosozialer Unterstützung bei Tumorpatienten in strahlentherapeutischer Behandlung. Strahlenther Onkol 174:408–414. https://doi.org/10.1007/BF03038562CrossRefPubMed

25.

Chen AM, Jennelle RLS, Grady V et al (2009) Prospective study of psychosocial distress among patients undergoing radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys 73:187–193. https://doi.org/10.1016/j.ijrobp.2008.04.010CrossRefPubMed

26.

Klug N, Butow PN, Burns M et al (2020) Unmasking anxiety: a qualitative investigation of health professionals; perspectives of mask anxiety in head and neck cancer. J Med Imaging Radiat Sci 51:12–21. https://doi.org/10.1016/j.jmir.2019.09.009CrossRefPubMed

27.

Thuné-Boyle ICV, Myers LB, Newman SP (2006) The role of illness beliefs, treatment beliefs, and perceived severity of symptoms in explaining distress in cancer patients during chemotherapy treatment. Behav Med 32:19–29. https://doi.org/10.3200/BMED.32.1.19-29CrossRefPubMed

28.

Letwin L, Silverman MJ (2017) No between-group difference but tendencies for patient support: A pilot study of a resilience-focused music therapy protocol for adults on a medical oncology/hematology unit. Arts Psychother 55:116–125. https://doi.org/10.1016/j.aip.2017.06.002CrossRef

29.

Rossetti A, Chadha M, Torres BN et al (2017) The impact of music therapy on anxiety in cancer patients undergoing simulation for radiation therapy. Int J Radiat Oncol Biol Phys 99:103–110. https://doi.org/10.1016/j.ijrobp.2017.05.003CrossRefPubMedPubMedCentral

30.

Soo MS, Jarosz JA, Wren AA et al (2016) Imaging-guided core-needle breast biopsy: impact of meditation and music interventions on patient anxiety, pain, and fatigue. J Am Coll Radiol 13:526–534. https://doi.org/10.1016/j.jacr.2015.12.004CrossRefPubMed

31.

Alcântara-Silva TR, de Freitas-Junior R, Freitas NMA et al (2018) Music therapy reduces radiotherapy-induced fatigue in patients with breast or gynecological cancer: a randomized trial. Integr Cancer Ther 17:628–635. https://doi.org/10.1177/1534735418757349CrossRefPubMedPubMedCentral

32.

Saito T, Murotani K, Yamaguchi K et al (2021) Influence of pain duration on pain outcomes following palliative radiotherapy for painful tumors: the sooner the irradiation, the better? Strahlenther Onkol 197:916–925. https://doi.org/10.1007/s00066-021-01760-xCrossRefPubMed

33.

Kal HB (1999) Single-dose radiotherapy for painful bone metastases. Strahlenther Onkol 175:495–499. https://doi.org/10.1007/s000660050060CrossRefPubMed

34.

Sauer N, Leising D, Wild B et al (2006) Pain and quality of life following palliative radiotherapy of bone metastases. Strahlenther Onkol 182:550–556. https://doi.org/10.1007/s00066-006-1510-3CrossRefPubMed

35.

Sahgal A, Myrehaug SD, Siva S et al (2021) Stereotactic body radiotherapy versus conventional external beam radiotherapy in patients with painful spinal metastases: an open-label, multicentre, randomised, controlled, phase 2/3 trial. Lancet Oncol 22:1023–1033. https://doi.org/10.1016/S1470-2045(21)00196-0CrossRefPubMed

36.

Chow E, Meyer RM, Ding K et al (2015) Dexamethasone in the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a double-blind, randomised placebo-controlled, phase 3 trial. Lancet Oncol 16:1463–1472. https://doi.org/10.1016/S1470-2045(15)00199-0CrossRefPubMed

37.

Skiba-Tatarska M, Kusa-Podkańska M, Surtel A, Wysokińska-Miszczuk J (2016) The side-effects of head and neck tumors radiotherapy. Pol Merkur Lekarski 41:47–49PubMed

38.

Selzer E, Liederer S, Lemaire C et al (2011) Incidence of dermatitis in head and neck cancer patients treated with primary radiotherapy and cetuximab. Strahlenther Onkol 187:373–377. https://doi.org/10.1007/s00066-011-2217-7CrossRefPubMed

39.

Janssen S, Käsmann L, Fahlbusch FB et al (2018) Side effects of radiotherapy in breast cancer patients : the internet as an information source. Strahlenther Onkol 194:136–142. https://doi.org/10.1007/s00066-017-1197-7CrossRefPubMed

40.

Hauth F, De-Colle C, Weidner N et al (2021) Quality of life and fatigue before and after radiotherapy in breast cancer patients. Strahlenther Onkol 197:281–287. https://doi.org/10.1007/s00066-020-01700-1CrossRefPubMed

41.

Clements-Cortés A (2016) Development and efficacy of music therapy techniques within palliative care. Complement Ther Clin Pract 23:125–129. https://doi.org/10.1016/j.ctcp.2015.04.004CrossRefPubMed

42.

Gallagher LM, Lagman R, Rybicki L (2018) Outcomes of music therapy interventions on symptom management in palliative medicine patients. Am J Hosp Palliat Care 35:250–257. https://doi.org/10.1177/1049909117696723CrossRefPubMed

43.

Gutgsell KJ, Schluchter M, Margevicius S et al (2013) Music therapy reduces pain in palliative care patients: a randomized controlled trial. J Pain Symptom Manage 45:822–831. https://doi.org/10.1016/j.jpainsymman.2012.05.008CrossRefPubMed

44.

O’Callaghan CC, McDermott F, Michael N et al (2014) “A quiet still voice that just touches”: music’s relevance for adults living with life-threatening cancer diagnoses. Support Care Cancer 22:1037–1047. https://doi.org/10.1007/s00520-013-2059-1CrossRefPubMed

45.

Nardone V, Vinciguerra C, Correale P et al (2020) Music therapy and radiation oncology: state of art and future directions. Complement Ther Clin Pract 39:101124. https://doi.org/10.1016/j.ctcp.2020.101124CrossRefPubMed

46.

Breivik EK, Björnsson GA, Skovlund E (2000) A comparison of pain rating scales by sampling from clinical trial data. Clin J Pain 16:22–28CrossRefPubMed

47.

Hjermstad MJ, Fayers PM, Haugen DF et al (2011) Studies comparing numerical rating scales, verbal rating scales, and visual analogue scales for assessment of pain intensity in adults: a systematic literature review. J Pain Symptom Manage 41:1073–1093. https://doi.org/10.1016/j.jpainsymman.2010.08.016CrossRefPubMed

48.

Maurer J, Schäfer C, Maurer O, Kölbl O (2012) Anxiety and depression in cancer patients during the course of radiotherapy treatment. Strahlenther Onkol 188:940–945. https://doi.org/10.1007/s00066-012-0143-yCrossRefPubMed

49.

Peck A, Boland J (1977) Emotional reactions to radiation treatment. Cancer 40:180–184CrossRefPubMed

50.

Wren AA, Shelby RA, Soo MS et al (2019) Preliminary efficacy of a lovingkindness meditation intervention for patients undergoing biopsy and breast cancer surgery: a randomized controlled pilot study. Support Care Cancer 27:3583–3592. https://doi.org/10.1007/s00520-019-4657-zCrossRefPubMed

51.

Verstegen AL, Silverman MJ (2018) Effects of music therapy on mood and pain with patients hospitalized for bone marrow transplantation: a randomized effectiveness pilot study. J Creat Ment Health 13:418–428. https://doi.org/10.1080/15401383.2018.1486257CrossRef

52.

Reimnitz L, Silverman MJ (2020) A randomized pilot study of music therapy in the form of patient-preferred live music on fatigue, energy and pain in hospitalized adult oncology patients on a blood and marrow transplant unit. Arts Health 12:154–168. https://doi.org/10.1080/17533015.2018.1534251CrossRefPubMed

53.

Tuinmann G, Preissler P, Böhmer H et al (2017) The effects of music therapy in patients with high-dose chemotherapy and stem cell support: a randomized pilot study. Psychooncology 26:377–384. https://doi.org/10.1002/pon.4142CrossRefPubMed

54.

Alam M, Roongpisuthipong W, Kim NA et al (2016) Utility of recorded guided imagery and relaxing music in reducing patient pain and anxiety, and surgeon anxiety, during cutaneous surgical procedures: a single-blinded randomized controlled trial. J Am Acad Dermatol 75:585–589. https://doi.org/10.1016/j.jaad.2016.02.1143CrossRefPubMed

55.

Bro ML, Johansen C, Vuust P et al (2019) Effects of live music during chemotherapy in lymphoma patients: a randomized, controlled, multi-center trial. Support Care Cancer 27:3887–3896. https://doi.org/10.1007/s00520-019-04666-8CrossRefPubMed

56.

Firmeza MA, Rodrigues AB, Melo GAA et al (2017) Control of anxiety through music in a head and neckoutpatient clinic: a randomized clinical trial. Rev Esc Enferm USP. https://doi.org/10.1590/S1980-220X2016030503201CrossRefPubMed

57.

Mou Q, Wang X, Xu H et al (2020) Effects of passive music therapy on anxiety and vital signs in lung cancer patients undergoing peripherally inserted central catheter placement procedure. J Vasc Access 21:875–882. https://doi.org/10.1177/1129729820908088CrossRefPubMed

58.

Burrai F, Micheluzzi V, Bugani V (2014) Effects of live sax music on various physiological parameters, pain level, and mood level in cancer patients: a randomized controlled trial. Holist Nurs Pract 28:301–311. https://doi.org/10.1097/HNP.0000000000000041CrossRefPubMed

59.

Chen L‑C, Wang T‑F, Shih Y‑N, Wu L‑J (2012) Fifteen-minute music intervention reduces pre-radiotherapy anxiety in oncology patients. Eur J Oncol Nurs. https://doi.org/10.1016/j.ejon.2012.11.002CrossRefPubMed

60.

Palmer JB, Lane D, Mayo D et al (2015) Effects of music therapy on anesthesia requirements and anxiety in women undergoing ambulatory breast surgery for cancer diagnosis and treatment: a randomized controlled trial. J Clin Oncol 33:3162–3168. https://doi.org/10.1200/JCO.2014.59.6049CrossRefPubMed

61.

Wang Y, Tang H, Guo Q et al (2015) Effects of intravenous patient-controlled sufentanil analgesia and music therapy on pain and hemodynamics after surgery for lung cancer: a randomized parallel study. J Altern Complement Med 21:667–672. https://doi.org/10.1089/acm.2014.0310CrossRefPubMed

Titel: Physical and nonphysical effects of weekly music therapy intervention on the condition of radiooncology patients
verfasst von: Patrick Clemens
Philipp Szeverinski
Peter Tschann
Marion Dietl
Joyce Gurk
Matthias Kowatsch
Gerhard Tucek
Alexander de Vries
Publikationsdatum: 24.12.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: Strahlentherapie und Onkologie / Ausgabe 3/2023
Print ISSN: 0179-7158
Elektronische ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-022-02033-x

Springer Medizin

Physical and nonphysical effects of weekly music therapy intervention on the condition of radiooncology patients