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01.09.2013

Pituitary stem cells: candidates and implications

verfasst von: Farshad Nassiri, Michael Cusimano, Jeff A. Zuccato, Safraz Mohammed, Fabio Rotondo, Eva Horvath, Luis V. Syro, Kalman Kovacs, Ricardo V. Lloyd

Erschienen in: Pituitary | Ausgabe 3/2013

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Abstract

The pituitary is the master endocrine gland of the body. It undergoes many changes after birth, and these changes may be mediated by the differentiation of pituitary stem cells. Stem cells in any tissue source must display (1) pluripotent capacity, (2) capacity for indefinite self-renewal, and (3) a lack of specialization. Unlike neural stem cells identified in the hippocampus and subventricular zone, pituitary stem cells are not associated with one specific cell type. There are many major candidates that are thought to be potential pituitary stem cell sources. This article reviews the evidence for each of the major cell types and discuss the implications of identifying a definitive pituitary stem cell type.

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Titel: Pituitary stem cells: candidates and implications
verfasst von: Farshad Nassiri
Michael Cusimano
Jeff A. Zuccato
Safraz Mohammed
Fabio Rotondo
Eva Horvath
Luis V. Syro
Kalman Kovacs
Ricardo V. Lloyd
Publikationsdatum: 01.09.2013
Verlag: Springer US
Erschienen in: Pituitary / Ausgabe 3/2013
Print ISSN: 1386-341X
Elektronische ISSN: 1573-7403
DOI: https://doi.org/10.1007/s11102-013-0470-8

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