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01.11.2020 | Review Article

Post-Thoracotomy Pain: Current Strategies for Prevention and Treatment

verfasst von: Ruchir Gupta, Thomas Van de Ven, Srinivas Pyati

Erschienen in: Drugs | Ausgabe 16/2020

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Abstract

Treating acute pain after thoracotomy surgery and preventing the development of chronic post-thoracotomy pain syndrome (PTPS) remain significant challenges in this surgical population. While appropriately treated acute thoracotomy pain often resolves, a significant number of patients develop PTPS, with up to 65% of patients experiencing some pain and 10% suffering life-altering, debilitating pain. Currently, there is very little known about specific molecular targets or novel therapeutic combinations that effectively prevent PTPS. Identifying modifiable clinical risk factors (procedure, physical and mental health, preoperative pain in the surgical area and another regions) seems to the most pragmatic approach for prevention for now. Effective acute pain management adopting a multimodal approach can result in a decreased incidence of PTPS. Interventional techniques such as paraverterbral blocks, intercostal blocks, and erector spinae blocks show some promise as well. Future research should be focused on minimally invasive surgeries and also the effect of ERAS protocols, including early mobilization, nutrition, and early removal of drains, on the development of PTPS.

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Titel: Post-Thoracotomy Pain: Current Strategies for Prevention and Treatment
verfasst von: Ruchir Gupta
Thomas Van de Ven
Srinivas Pyati
Publikationsdatum: 01.11.2020
Verlag: Springer International Publishing
Erschienen in: Drugs / Ausgabe 16/2020
Print ISSN: 0012-6667
Elektronische ISSN: 1179-1950
DOI: https://doi.org/10.1007/s40265-020-01390-0

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Post-Thoracotomy Pain: Current Strategies for Prevention and Treatment

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Live-Webinar "Urologie und Sexualmedizin in der Praxis"

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