Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende
Erweiterte Suche
Anmelden
nach oben
AIDS and Behavior
Erschienen in: AIDS and Behavior 5/2020

13.11.2019 | Original Paper

Preferences for Pre-exposure Prophylaxis Service Delivery Among Female Sex Workers in Malawi: A Discrete Choice Experiment

verfasst von: Kathryn E. Lancaster, Thandie Lungu, Agatha Bula, Jaclyn M. Shea, Abigail Shoben, Mina C. Hosseinipour, Racquel E. Kohler, Irving F. Hoffman, Vivian F. Go, Carol E. Golin, Stephanie B. Wheeler, William C. Miller

Erschienen in: AIDS and Behavior | Ausgabe 5/2020

Einloggen, um Zugang zu erhalten

Abstract

Female sex workers (FSW) in Malawi have among the highest HIV prevalence estimates worldwide. Daily oral pre-exposure prophylaxis (PrEP) is an effective HIV prevention method, yet preferences for PrEP delivery among FSW are lacking. Eight focus group discussions, a literature review, and cognitive interviews were conducted to identify modifiable PrEP delivery attributes and inform discrete-choice experiment (DCE) development for FSW in Lilongwe. Enrolled FSW received an interviewer-assisted DCE. Data were analyzed using mixed logit regression. Dispensing location was most preferred, followed by the provision of additional services. Women preferred receiving PrEP at family planning clinics or non-governmental organization run drop-in centers. Cervical cancer screening was the most preferred additional service, while pregnancy testing and partner risk reduction counseling were less valued. This study was the first study to examine PrEP delivery preferences in Malawi using DCE—a powerful elicitation tool to apply to other key populations at risk for HIV.
Literatur
1.
World Health Organization (WHO). Prevention and treatment of HIV and other sexually transmitted infections for sex workers in low- and middle-income countries: Recommendations for a public health approach. Geneva, Switzerland; 2013.
2.
Baral S, Beyrer C, Muessig K, Poteat T, Wirtz AL, Decker MR, et al. Burden of HIV among female sex workers in low-income and middle-income countries: a systematic review and meta-analysis. The Lancet Infectious Diseases. 2012.
3.
Matovu J, Ssebadduka B. Sexual risk behaviours, condom use and sexually transmitted infection treatment-seeking behaviours among female sex workers and truck drivers in Uganda. Int J STD AIDS. 2012;23(4):267–73.PubMed
4.
Scorgie F, Chersich MF, Ntaganira I, Gerbase A, Lule F, Lo YR. Socio-demographic characteristics and behavioral risk factors of female sex workers in sub-saharan Africa: a systematic review. AIDS Behav. 2012;16(4):920–33.PubMed
5.
Vuylsteke B, Semdé G, Sika L, Crucitti T, Traoré VE, Buvé A, et al. HIV and STI Prevalence among Female Sex Workers in Côte d’Ivoire: Why Targeted Prevention Programs Should Be Continued and Strengthened. PLoS ONE. 2012;7(3):e32627.PubMedPubMedCentral
6.
Zachariah R, Spielmann M, Harries A, Nkhoma W, Chantulo A, Arendt V. Sexually transmitted infections and sexual behaviour among commercial sex workers in a rural district of Malawi. Int J STD AIDS. 2003;14(3):185–8.PubMed
7.
Lancaster KE, Powers KA, Lungu T, Mmodzi P, Hosseinipour MC, Chadwick K, et al. The HIV Care Continuum among Female Sex Workers: a Key Population in Lilongwe, Malawi. PLoS ONE. 2016;11(1):e0147662.PubMedPubMedCentral
8.
President of the Republic of Malawi. 2012 Global AIDS Response Progress Report: Malawi Country Report for 2010 and 2011. 2012.
9.
Family Planning Association of Malawi. Counting the uncatchables: Report of the situation analysis of the magnitude, behavioral patterns, contributing factors, current interventions and impact of sex work in HIV prevention in Malawi. Lilongwe: Family Planning Association of Malawi; 2011.
10.
Baeten JM, Donnell D, Ndase P, Mugo NR, Campbell JD, Wangisi J, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012;367(5):399–410.PubMedPubMedCentral
11.
Thigpen MC, Kebaabetswe PM, Paxton LA, Smith DK, Rose CE, Segolodi TM, et al. Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana. N Engl J Med. 2012;367(5):423–34.PubMed
12.
Bekker LG, Johnson L, Cowan F, Overs C, Besada D, Hillier S, et al. Combination HIV prevention for female sex workers: what is the evidence? Lancet. 2015;385(9962):72–87.PubMed
13.
Murnane PM, Celum C, Mugo N, Campbell JD, Donnell D, Bukusi E, et al. Efficacy of preexposure prophylaxis for HIV-1 prevention among high-risk heterosexuals: subgroup analyses from a randomized trial. AIDS. 2013;27(13):2155–60.PubMed
14.
Kahle EM, Hughes JP, Lingappa JR, John-Stewart G, Celum C, Nakku-Joloba E, et al. An empiric risk scoring tool for identifying high-risk heterosexual HIV-1-serodiscordant couples for targeted HIV-1 prevention. J Acquir Immune Defic Syndr. 2013;62(3):339–47.PubMedPubMedCentral
15.
Marrazzo JM, Ramjee G, Richardson BA, Gomez K, Mgodi N, Nair G, et al. Tenofovir-based preexposure prophylaxis for HIV infection among African women. N Engl J Med. 2015;372(6):509–18.PubMedPubMedCentral
16.
Van Damme L, Corneli A, Ahmed K, Agot K, Lombaard J, Kapiga S, et al. Preexposure prophylaxis for HIV infection among African women. N Engl J Med. 2012;367(5):411–22.PubMedPubMedCentral
17.
Gomez GB, Eakle R, Mbogua J, Akpomiemie G, Venter WDF, Rees H. Treatment And Prevention for female Sex workers in South Africa: protocol for the TAPS Demonstration Project. BMJ Open. 2016;6(9):e011595.PubMedPubMedCentral
18.
Ware NC, Wyatt MA, Haberer JE, Baeten JM, Kintu A, Psaros C, et al. What’s love got to do with it? Explaining adherence to oral antiretroviral pre-exposure prophylaxis for HIV-serodiscordant couples. J Acquir Immune Defic Syndr. 2012;59(5):463–8.PubMed
19.
O’Laughlin KN, Wyatt MA, Kaaya S, Bangsberg DR, Ware NC. How treatment partners help: social analysis of an African adherence support intervention. AIDS Behav. 2012;16(5):1308–15.PubMed
20.
van der Straten A, Stadler J, Montgomery E, Hartmann M, Magazi B, Mathebula F, et al. Women’s experiences with oral and vaginal pre-exposure prophylaxis: the VOICE-C qualitative study in Johannesburg, South Africa. PLoS ONE. 2014;9(2):e89118.PubMedPubMedCentral
21.
Guest G, Shattuck D, Johnson L, Akumatey B, Clarke EE, Chen PL, et al. Changes in sexual risk behavior among participants in a PrEP HIV prevention trial. Sex Transm Dis. 2008;35(12):1002–8.PubMed
22.
Fearon E, Phillips A, Mtetwa S, Chabata ST, Mushati P, Cambiano V, et al. How can programmes better support female sex workers to avoid HIV infection in Zimbabwe? A prevention cascade analysis. J Acquir Immune Defic Syndr. 2019;81(1):24.PubMedPubMedCentral
23.
Lancaster KE, Cernigliaro D, Zulliger R, Fleming PF. HIV care and treatment experiences among female sex workers living with HIV in sub-Saharan Africa: a systematic review. Afr J AIDS Res. 2016;15(4):377–86.PubMedPubMedCentral
24.
Mangham LJ, Hanson K, McPake B. How to do (or not to do)… Designing a discrete choice experiment for application in a low-income country. Health Policy Plan. 2009;24(2):151–8.PubMed
25.
Lancaster KJ. A new approach to consumer theory. J Polit Econ. 1966;74(2):132–57.
26.
McFadden D. Conditional logit analysis of qualitative choice behavior. 1973.
27.
Pfarr C, Schmid A, Schneider U. Using discrete choice experiments to understand preferences in health care. Dev Health Econ Public Policy. 2014;12:27–48.PubMed
28.
Street DJ, Burgess L. The construction of optimal stated choice experiments: theory and methods. New York: Wiley; 2007.
29.
Muhlbacher AC, Stoll M, Mahlich J, Nubling M. Patient preferences for HIV/AIDS therapy—a discrete choice experiment. Health Econ Rev. 2013;3(1):14.PubMedPubMedCentral
30.
Minnis AM, Browne EN, Boeri M, Agot K, van der Straten A, Ahmed K, et al. Young Women’s stated preferences for biomedical HIV prevention: results of a discrete choice experiment in Kenya and South Africa. JAIDS J Acquir Immune Defic Syndr. 2019;80(4):394–403.PubMed
31.
Terris-Prestholt F, Hanson K, MacPhail C, Vickerman P, Rees H, Watts C. How much demand for New HIV prevention technologies can we really expect? Results from a discrete choice experiment in South Africa. PLoS ONE. 2013;8(12):e83193.PubMedPubMedCentral
32.
Quaife M, Eakle R, Cabrera Escobar MA, Vickerman P, Kilbourne-Brook M, Mvundura M, et al. Divergent preferences for HIV prevention: a discrete choice experiment for multipurpose HIV prevention products in South Africa. Med Decis Mak. 2018;38(1):120–33.
33.
Ye L, Wei S, Zou Y, Yang X, Abdullah AS, Zhong X, et al. HIV pre-exposure prophylaxis interest among female sex workers in Guangxi, China. PLoS ONE. 2014;9(1):e86200.PubMedPubMedCentral
34.
Wheelock A, Eisingerich AB, Ananworanich J, Gomez GB, Hallett TB, Dybul MR, et al. Are Thai MSM willing to take PrEP for HIV prevention? An analysis of attitudes, preferences and acceptance. PLoS ONE. 2013;8(1):e54288.PubMedPubMedCentral
35.
Braun V, Clarke V. Using thematic analysis in psychology. Qual Res Psychol. 2006;3(2):77–101.
36.
Bridges JF, Hauber AB, Marshall D, Lloyd A, Prosser LA, Regier DA, et al. Conjoint analysis applications in health—a checklist: a report of the ISPOR good research practices for conjoint analysis task force. Value Health. 2011;14(4):403–13.PubMed
37.
Hauber AB, Gonzalez JM, Groothuis-Oudshoorn CG, Prior T, Marshall DA, Cunningham C, et al. Statistical methods for the analysis of discrete choice experiments: a report of the ISPOR conjoint analysis good research practices task force. Value Health. 2016;19(4):300–15.PubMed
38.
Reed Johnson F, Lancsar E, Marshall D, Kilambi V, Muhlbacher A, Regier DA, et al. Constructing experimental designs for discrete-choice experiments: report of the ISPOR Conjoint Analysis Experimental Design Good Research Practices Task Force. Value Health. 2013;16(1):3–13.PubMed
39.
Kohler RE, Gopal S, Lee CN, Weiner BJ, Reeve BB, Wheeler SB. Breast cancer knowledge, behaviors, and preferences in Malawi: implications for early detection interventions from a discrete choice experiment. J Glob Oncol. 2017;3(5):480–9.PubMedPubMedCentral
40.
Marshall D, Bridges JF, Hauber B, Cameron R, Donnalley L, Fyie K, et al. Conjoint analysis applications in health—how are studies being designed and reported?: An update on current practice in the published literature between 2005 and 2008. Patient. 2010;3(4):249–56.PubMed
41.
Herce ME, Miller WM, Bula A, Edwards JK, Sapalalo P, Lancaster KE, et al. Achieving the first 90 for key populations in sub-Saharan Africa through venue-based outreach: challenges and opportunities for HIV prevention based on PLACE study findings from Malawi and Angola. J Int AIDS Soc. 2018;21(Suppl 5(Suppl Suppl 5)):e25132.PubMedPubMedCentral
42.
World Health Organization. Guideline on when to start ART and on PrEP for HIV. Geneva: WHO; 2015.
43.
Malawi National AIDS Commission. National HIV prevention strategy: 2015-2020. Malawi: Lilonwe; 2015.
44.
The Secretary for Health and Population. Malawi HIV policy updates: the Government of Malawi’s Commitment and plan to reach HIV epidemic control through 90-90-90 in Malawi by 2020. Lilongwe: The Secretary for Health and Population; 2019.
45.
Rendina HJ, Whitfield THF, Grov C, Starks TJ, Parsons JT. Distinguishing hypothetical willingness from behavioral intentions to initiate HIV pre-exposure prophylaxis (PrEP): findings from a large cohort of gay and bisexual men in the U.S. Soc Sci Med. 2017;172:115–23.PubMed
46.
Gorman SE, Martinez JM, Olson J. An assessment of HIV treatment outcomes among utilizers of semi-mobile clinics in rural Kenya. AIDS Care. 2015;27(5):665–8.PubMed
47.
Nakanwagi S, Matovu JKB, Kintu BN, Kaharuza F, Wanyenze RK. Facilitators and barriers to linkage to HIV care among female sex workers receiving HIV testing services at a community-based organization in Periurban Uganda: a qualitative study. J Sex Transm Dis. 2016;2016:7673014.PubMedPubMedCentral
48.
Campos PE, Buffardi AL, Carcamo CP, Garcia PJ, Buendia C, Chiappe M, et al. Reaching the unreachable: providing STI control services to female sex workers via mobile team outreach. PLoS ONE. 2013;8(11):e81041.PubMedPubMedCentral
49.
Mulongo S, Kapila G, Hatton T, Canagasabey D, Arney J, Kazadi T, et al. Applying innovative approaches for reaching men who have sex with men and female sex workers in the Democratic Republic of Congo. J Acquir Immune Defic Syndr. 2015;68(Suppl 2):S248–51.PubMed
50.
51.
Vlassoff M, et al. Benefits of meeting the contraceptive needs of Malawian women, In Brief. New York: Guttmacher Institute; 2014.
52.
53.
Scorgie F, Nakato D, Harper E, Richter M, Maseko S, Nare P, et al. ‘We are despised in the hospitals’: sex workers’ experiences of accessing health care in four African countries. Cult Health Sex. 2013;15(4):450–65.PubMed
54.
Lafort Y, Greener R, Roy A, Greener L, Ombidi W, Lessitala F, et al. Sexual and reproductive health services utilization by female sex workers is context-specific: results from a cross-sectional survey in India, Kenya, Mozambique and South Africa. Reprod Health. 2017;14(1):13.PubMedPubMedCentral
Metadaten
Titel
Preferences for Pre-exposure Prophylaxis Service Delivery Among Female Sex Workers in Malawi: A Discrete Choice Experiment
verfasst von
Kathryn E. Lancaster
Thandie Lungu
Agatha Bula
Jaclyn M. Shea
Abigail Shoben
Mina C. Hosseinipour
Racquel E. Kohler
Irving F. Hoffman
Vivian F. Go
Carol E. Golin
Stephanie B. Wheeler
William C. Miller
Publikationsdatum
13.11.2019
Verlag
Springer US
Erschienen in
AIDS and Behavior / Ausgabe 5/2020
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-019-02705-3

Weitere Artikel der Ausgabe 5/2020

AIDS and Behavior 5/2020 Zur Ausgabe

Original Paper

Can Self-Management Improve HIV Treatment Engagement, Adherence, and Retention? A Mixed Methods Evaluation in Tanzania and Uganda

Original Paper

Associations Between Relationship Power and Pre-Exposure Prophylaxis (PrEP) Use Among Men Who Have Sex With Men

Original Paper

Social Determinants of Potential eHealth Engagement Among People Living with HIV Receiving Ryan White Case Management: Health Equity Implications from Project TECH

Original Paper

The Unanticipated Benefits of PrEP for Young Black Gay, Bisexual, and Other Men Who Have Sex with Men

Original Paper

Efficacy is Not Everything: Eliciting Women’s Preferences for a Vaginal HIV Prevention Product Using a Discrete-Choice Experiment

Original Paper

Effects of a Combined Exercise Training Program on Health Indicators and Quality of Life of People Living with HIV: A Randomized Clinical Trial

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

25.04.2024 Allergien und Intoleranzreaktionen Nachrichten

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen
Bildnachweise