nach oben

Journal of Cancer Survivorship

Erschienen in:

22.08.2019

Prevalence of cardiovascular disease and risk factors, quality of life, and health behaviors of cancer survivors and their spouses: findings from MEPS

verfasst von: Lixin Song, Ting Guan, Peiran Guo, Thomas C. Keyserling, Courtney Van Houtven, Xianming Tan

Erschienen in: Journal of Cancer Survivorship | Ausgabe 5/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Few population-based studies have examined the prevalence of cardiovascular disease (CVD) and risk factors, quality of life (QOL), and health behaviors of cancer survivors and their spouses. This case-control study aimed to fill this gap using the data from a set of large-scale surveys of individuals and families across the USA.

Methods

Data were obtained from the 2010–2015 Medical Expenditure Panel Survey (MEPS). Using one-to-many (1:5) propensity score matching, we identified cancer survivors (N = 1037) and noncancer-matched controls (N = 5185), as well as survivor spouses (N = 1038) and matched controls (N = 5190). We used weighted multivariable logistic and linear regressions to examine the categorical and numerical outcomes.

Results

Compared with noncancer controls, survivors have higher rates of stroke (p < .05), hypertension (p < .05), high cholesterol (p < .01), fair or poor health (p < .0001), and report self-reported worse physical QOL scores (PCS) (p < .0001). A higher percentage of survivors report receiving BP checks (p < .01), serum cholesterol assessments (p < .001), routine physical checkups (p < .01), blood stool tests (p < .05), colonoscopies (p < .0001), and flu vaccinations (p < .05). Survivor spouses, compared to their respective matched controls, reported higher rates of serum cholesterol testing (p < .001), routine physical checkups (p < .01), and flu vaccinations (p < .01).

Conclusions

Compared to the general population, cancer survivors are at higher risk for CVD, report worse physical QOL, and, along with their spouses, more frequently receive certain preventive health care services.

Implications for Cancer Survivors

There is a need for intervention to more fully engage cancer survivors and spouses in lifestyle behavior change associated with decreased CVD and related risk factors and improved QOL.

National Cancer Institution. Cancer statistics. 2018. https://www.cancer.gov/about-cancer/understanding/statistics. Accessed 6 Jan 2019.

Edwards BK, Noone AM, Mariotto AB, Simard EP, Boscoe FP, Henley SJ, et al. Annual report to the nation on the status of cancer, 1975-2010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer. Cancer. 2014;120:1290–314.CrossRefPubMed

Zaorsky NG, Churilla TM, Egleston BL, Fisher SG, Ridge JA, Horwitz EM, et al. Causes of death among cancer patients. Ann Oncol. 2017;28:400–7.PubMed

Centers for Disease Control and Prevention. Conditions that increase risk for heart disease. 2019. https://www.cdc.gov/heartdisease/conditions.htm. Accessed 6 Jan 2019.

Van de Poll-Franse LV, Sadetsky N, Kwan L, Litwin MS. Severity of cardiovascular disease and health-related quality of life in men with prostate cancer: a longitudinal analysis from CaPSURE. Qual Life Res. 2008;17:845–55.CrossRefPubMedPubMedCentral

Schoormans D, Czene K, Hall P, Brandberg Y. The impact of co-morbidity on health-related quality of life in breast cancer survivors and controls. Acta Oncol. 2015;54:727–34.CrossRefPubMed

Denlinger CS, Ligibel JA, Are M, Baker KS, Broderick G, Demark-Wahnefried W, et al. NCCN guidelines insights: survivorship, version 1. 2016. J Natl Compr Cancer Netw. 2016;14:715–24.CrossRef

Demark-Wahnefried W, Rogers LQ, Alfano CM, Thomson CA, Courneya KS, Meyerhardt JA, et al. Practical clinical interventions for diet, physical activity, and weight control in cancer survivors. CA Cancer J Clin. 2015;65:167–89.CrossRefPubMed

Kasl SV, Cobb S. Health behavior, illness behavior and sick role behavior: I. Health and illness behavior. Arch Environ Health. 1966;12:246–66.CrossRefPubMed

10.

McCullough ML, Patel AV, Kushi LH, Patel R, Willett WC, Doyle C, et al. Following cancer prevention guidelines reduces risk of cancer, cardiovascular disease, and all-cause mortality. Cancer Epidemiol Biomark Prev. 2011;20:1089–97.CrossRef

11.

Schwingshackl L, Bogensberger B, Hoffmann G. Diet quality as assessed by the healthy eating index, alternate healthy eating index, dietary approaches to stop hypertension score, and health outcomes: an updated systematic review and meta-analysis of cohort studies. J Acad Nutr Diet. 2018;118:74–100.CrossRefPubMed

12.

Jones LW, Habel LA, Weltzien E, Castillo A, Gupta D, Kroenke CH, et al. Exercise and risk of cardiovascular events in women with nonmetastatic breast cancer. J Clin Oncol. 2016;34:2743–9.CrossRefPubMedPubMedCentral

13.

Sturgeon KM, Ky B, Libonati JR, Schmitz KH. The effects of exercise on cardiovascular outcomes before, during, and after treatment for breast cancer. Breast Cancer Res Treat. 2014;143:219–26.CrossRefPubMed

14.

Keats MR, Cui Y, Grandy SA, Parker L. Cardiovascular disease and physical activity in adult cancer survivors: a nested, retrospective study from the Atlantic PATH cohort. J Cancer Surviv. 2017;11:264–73.CrossRefPubMed

15.

Bluethmann SM, Basen-Engquist K, Vernon SW, Cox M, Gabriel KP, Stansberry SA, et al. Grasping the ‘teachable moment’: time since diagnosis, symptom burden and health behaviors in breast, colorectal and prostate cancer survivors. Psychooncology. 2015;24:1250–7.CrossRefPubMedPubMedCentral

16.

Hawkins NA, Smith T, Zhao L, Rodriguez J, Berkowitz Z, Stein KD. Health-related behavior change after cancer: results of the American Cancer Society’s studies of cancer survivors (SCS). J Cancer Surviv. 2010;4:20–32.CrossRefPubMed

17.

Centers for Disease Control and Prevention. Surveillance of demographic characteristics and health behaviors among adult cancer survivors—behavioral risk factor surveillance system, United States, 2009. MMWR. 2012;61:1–23.

18.

Romito F, Goldzweig G, Cormio C, Hagedoorn M, Andersen BL. Informal caregiving for cancer patients. Cancer. 2013;119:2160–9.CrossRefPubMed

19.

Kent EE, Rowland JH, Northouse L, Litzelman K, Chou WY, Shelburne N, et al. Caring for caregivers and patients: research and clinical priorities for informal cancer caregiving. Cancer. 2016;122:1987–95.CrossRefPubMed

20.

Gregorio SW, Carpenter KM, Dorfman CS, Yang HC, Simonelli LE, Carson WE III. Impact of breast cancer recurrence and cancer-specific stress on spouse health and immune function. Brain Behav Immun. 2012;26:228–33.CrossRefPubMed

21.

Ji J, Zoller B, Sundquist K, Sundquist J. Increased risks of coronary heart disease and stroke among spousal caregivers of cancer patients. Circulation. 2012;125:1742–7.CrossRefPubMed

22.

Kim Y, Spillers RL, Hall DL. Quality of life of family caregivers 5 years after a relative’s cancer diagnosis: follow-up of the national quality of life survey for caregivers. Psychooncology. 2012;21:273–81.CrossRefPubMed

23.

Mazanec SR, Flocke SA, Daly BJ. Health behaviors in family members of patients completing cancer treatment. Oncol Nurs Forum. 2015;42:54–62.CrossRefPubMedPubMedCentral

24.

Son KY, Park SM, Lee CH, Choi GJ, Lee D, Jo S, et al. Behavioral risk factors and use of preventive screening services among spousal caregivers of cancer patients. Support Care Cancer. 2011;19:919–27.CrossRefPubMed

25.

Litzelman K, Kent EE, Rowland JH. Interrelationships between health behaviors and coping strategies among informal caregivers of cancer survivors. Health Educ Behav. 2018;45:90–100.CrossRefPubMed

26.

Miller KD, Siegel RL, Lin CC, Mariotto AB, Kramer JL, Rowland JH, et al. Cancer treatment and survivorship statistics, 2016. CA Cancer J Clin. 2016;66:271–89.CrossRefPubMed

27.

Lee Y, Lin PY, Chien CY, Fang FM, Wang LJ. A comparison of psychological well-being and quality of life between spouse and non-spouse caregivers in patients with head and neck cancer: a 6-month follow-up study. Neuropsychiatr Dis Treat. 2018;14:1697–704.CrossRefPubMedPubMedCentral

28.

Yabroff KR, Dowling E, Rodriguez J, Ekwueme DU, Meissner H, Soni A, et al. The Medical Expenditure Panel Survey (MEPS) experiences with cancer survivorship supplement. J Cancer Surviv. 2012;6:407–19.CrossRefPubMedPubMedCentral

29.

American Cancer Society. Cancer facts & figures 2010. 2010. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2010/cancer-facts-and-figures-2010.pdf. Accessed 6 Jan 2019.

30.

American Cancer Society. Cancer facts & figures 2011. 2011. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2011/cancer-facts-and-figures-2011.pdf. Accessed 6 Jan 2019.

31.

American Cancer Society. Cancer facts & figures 2012. 2012. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2012/cancer-facts-and-figures-2012.pdf. Accessed 6 Jan 2019.

32.

American Cancer Society. Cancer facts & figures 2013. 2013. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2013/cancer-facts-and-figures-2013.pdf. Accessed 6 Jan 2019.

33.

American Cancer Society. Cancer facts & figures 2014. 2014. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2014/cancer-facts-and-figures-2014.pdf. Accessed 6 Jan 2019.

34.

American Cancer Society. Cancer facts & figures 2015. 2015. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2015/cancer-facts-and-figures-2015.pdf. Accessed 6 Jan 2019.

35.

American Heart Association. What is cardiovascular disease? 2017. https://www.heart.org/en/health-topics/consumer-healthcare/what-is-cardiovascular-disease. Accessed 6 Jan 2019.

36.

Agency for Healthcare Research and Quality. MEPS HC-181: 2015 full year population characteristics. 2017. https://meps.ahrq.gov/data_stats/download_data_files_detail.jsp?cboPufNumber=HC-181. Accessed 6 Jan 2019.

37.

Hayes CJ, Bhandari NR, Kathe N, Payakachat N. Reliability and validity of the Medical Outcomes Study Short Form-12 Version 2 (SF-12v2) in adults with non-cancer pain. Healthcare. 2017;5:22.CrossRefPubMedCentral

38.

Hays RD, Spritzer KL, Thompson WW, Cella D. U.S. general population estimate for “excellent” to “poor” self-rated health item. J Gen Intern Med. 2015;30:1511–6.CrossRefPubMedPubMedCentral

39.

U.S. Preventive Services Task Force. USPSTF A and B recommendations by date. 2018. https://www.uspreventiveservicestaskforce.org/Page/Name/uspstf-a-and-b-recommendations-by-date/. Accessed 20 Nov 2018.

40.

World Health Organization. What is moderate-intensity and vigorous-intensity physical activity? n.d. https://www.who.int/dietphysicalactivity/physical_activity_intensity/en/. Accessed 9 Jan 2019.

41.

Centers for Disease Controls and Prevention. Defining adult overweight and obesity. 2017. https://www.cdc.gov/obesity/adult/defining.html. Accessed 29 Jan 2019.

42.

Ho DE, Imai K, King G, Stuart EA. MatchIt: nonparametric preprocessing for parametric causal inference. J Stat Softw. 2011;42.

43.

Rassen JA, Shelat AA, Myers J, Glynn RJ, Rothman KJ, Schneeweiss S. Optimal approaches to one-to-many propensity score matching in cohort studies. Pharmacoepidemiol Drug Saf Pharmacoepidemiology and Drug Safety. 2012;21:34–5.CrossRef

44.

Agency for Healthcare Research and Quality. MEPS HC-138: 2010 full year consolidated data file. 2012. https://meps.ahrq.gov/data_stats/download_data/pufs/h138/h138doc.shtml#254Income. Accessed 1 Dec 2018.

45.

Agency for Healthcare Research and Quality. Using statistical software packages to produce estimates from MEPS data files. n.d. https://meps.ahrq.gov/survey_comp/hc_samplecodes_se.shtml. Accessed 14 Dec 2018.

46.

Resseguier N, Giorgi R, Paoletti X. Sensitivity analysis when data are missing not-at-random. Epidemiology. 2011;22:282.CrossRefPubMed

47.

Mishra SI, Scherer RW, Geigle PM, Berlanstein DR, Topaloglu O, Gotay CC, et al. Exercise interventions on health-related quality of life for cancer survivors. Cochrane Database Syst Rev. 2012;8:CD007566.

48.

Mishra SI, Scherer RW, Snyder C, Geigle PM, Berlanstein DR, Topaloglu O. Exercise interventions on health-related quality of life for people with cancer during active treatment. Cochrane Database Syst Rev. 2012;8:CD008465.

49.

Kenfield SA, DuPre N, Richman EL, Stampfer MJ, Chan JM, Giovannucci EL. Mediterranean diet and prostate cancer risk and mortality in the Health Professionals Follow-up Study. Eur Urol. 2014;65:887–94.CrossRefPubMed

50.

Aleman BM, Moser EC, Nuver J, Suter TM, Maraldo MV, Specht L, et al. Cardiovascular disease after cancer therapy. EJC Suppl. 2014;12:18–28.CrossRefPubMedPubMedCentral

51.

Armenian SH, Xu L, Ky B, Sun C, Farol LT, Pal SK, et al. Cardiovascular disease among survivors of adult-onset cancer: a community-based retrospective cohort study. J Clin Oncol. 2016;34:1122–30.CrossRefPubMedPubMedCentral

52.

Courneya KS, Katzmarzyk PT, Bacon E. Physical activity and obesity in Canadian cancer survivors: population-based estimates from the 2005 Canadian Community Health Survey. Cancer. 2008;112:2475–82.CrossRefPubMed

53.

Bellizzi KM, Rowland JH, Jeffery DD, McNeel T. Health behaviors of cancer survivors: examining opportunities for cancer control intervention. J Clin Oncol. 2005;23:8884–93.CrossRefPubMed

54.

Shih YC, Pan IW. Influenza vaccination among individuals with cancer and their family members. Am J Prev Med. 2010;38:61–9.CrossRefPubMed

55.

Fairley TL, Hawk H, Pierre S. Health behaviors and quality of life of cancer survivors in Massachusetts, 2006: data use for comprehensive cancer control. Prev Chronic Dis. 2010;7.

56.

Di Castelnuovo A, Quacquaruccio G, Donati MB, de Gaetano G, Iacoviello L. Spousal concordance for major coronary risk factors: a systematic review and meta-analysis. Am J Epidemiol. 2009;169:1–8.CrossRefPubMed

57.

Reblin M, Birmingham WC, Kohlmann W, Graff T. Support and negation of colorectal cancer risk prevention behaviors: analysis of spousal discussions. Psychol Health Med. 2018;23:548–54.CrossRefPubMed

58.

Falba TA, Sindelar JL. Spousal concordance in health behavior change. Health Serv Res. 2008;43:96–116.CrossRefPubMedPubMedCentral

59.

Gritz ER, Fingeret MC, Vidrine DJ, Lazev AB, Mehta NV, Reece GP. Successes and failures of the teachable moment: smoking cessation in cancer patients. Cancer. 2006;106:17–27.CrossRefPubMed

60.

Centers for Disease Control and Prevention. Heart disease facts. 2017. https://www.cdc.gov/heartdisease/facts.htm. Accessed 1 May 2019.

61.

Correia LCL. Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts. N Engl J Med. 2018;379:e34.CrossRef

62.

de Lorgeril M, Renaud S, Mamelle N, Salen P, Martin JL, Monjaud I, et al. Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet. 1994;343:1454–9.CrossRefPubMed

63.

U.S. Department of Health and Human Services. The health consequences of smoking—50 years of progress: a report of the surgeon general. 2014. https://www.ncbi.nlm.nih.gov/books/NBK179276/pdf/Bookshelf_NBK179276.pdf. Accessed 29 June2019.

64.

Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation. 2006;113:898–918.CrossRefPubMed

65.

Li J, Siegrist J. Physical activity and risk of cardiovascular disease—a meta-analysis of prospective cohort studies. Int J Environ Res Public Health. 2012;9:391–407.CrossRefPubMedPubMedCentral

Titel: Prevalence of cardiovascular disease and risk factors, quality of life, and health behaviors of cancer survivors and their spouses: findings from MEPS
verfasst von: Lixin Song
Ting Guan
Peiran Guo
Thomas C. Keyserling
Courtney Van Houtven
Xianming Tan
Publikationsdatum: 22.08.2019
Verlag: Springer US
Erschienen in: Journal of Cancer Survivorship / Ausgabe 5/2019
Print ISSN: 1932-2259
Elektronische ISSN: 1932-2267
DOI: https://doi.org/10.1007/s11764-019-00792-8

Neu im Fachgebiet Onkologie

25.04.2024 | Nierenkarzinom | Nachrichten

Springer Medizin

Prevalence of cardiovascular disease and risk factors, quality of life, and health behaviors of cancer survivors and their spouses: findings from MEPS

Abstract

Purpose

Methods

Results

Conclusions

Implications for Cancer Survivors

Neu im Fachgebiet Onkologie

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Bei Senioren mit Prostatakarzinom auf Anämie achten!

ICI-Therapie in der Schwangerschaft wird gut toleriert

Update Onkologie

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

Implications for Cancer Survivors

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 5/2019

Implementing physical activity programs for patients with cancer in current practice: patients’ experienced barriers and facilitators

Subjective cognitive functioning and associations with psychological distress in adult brain tumour survivors

Drivers of cost differences between US breast cancer survivors with or without lymphedema

Cancer specialist nurses’ perspectives of physical activity promotion and the potential role of physical activity apps in cancer care

The relationship between diet and cognitive function in adult cancer survivors: a systematic review

Nicotinic treatment of post-chemotherapy subjective cognitive impairment: a pilot study

Neu im Fachgebiet Onkologie

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Bei Senioren mit Prostatakarzinom auf Anämie achten!

ICI-Therapie in der Schwangerschaft wird gut toleriert

Update Onkologie