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Brain Structure and Function

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12.07.2021 | Review

Prevalence of the interthalamic adhesion in the human brain: a review of literature

verfasst von: Andrew K. Wong, Daniel I. Wolfson, Alireza Borghei, Sepehr Sani

Erschienen in: Brain Structure and Function | Ausgabe 8/2021

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Abstract

The interthalamic adhesion (IA) is a midline structure connecting the two thalami. Though it has been studied for centuries its exact function remains elusive. Early studies had noted its peculiar absence even among some healthy individuals. Population studies have investigated the differences in prevalence of IA in pathologic conditions and healthy controls. However, there is a general lack of consensus on IA prevalence in the healthy population. Understanding the true prevalence is critical in providing context for future studies, as well as uncovering further clues regarding IA’s function. We systematically reviewed the existing literature to evaluate the prevalence of IA. The average prevalence among reviewed studies was higher than previously reported, at 87.3%. Studies utilizing magnetic resonance imaging rather than cadaveric specimens reported higher rates of IA prevalence. A higher prevalence among females was noted throughout the literature that persisted regardless of acquisition modality utilized.

Agarwal N, Rambaldelli G, Perlini C, Dusi N, Kitis O, Bellani M, Cerini R, Isola M, Versace A, Balestrieri M, Gasparini A, Mucelli RP, Tansella M, Brambilla P (2008) Microstructural thalamic changes in schizophrenia: a combined anatomic and diffusion weighted magnetic resonance imaging study. J Psychiatry Neurosci 33(5):440–448PubMedPubMedCentral

Allen LS, Gorski RA (1991) Sexual dimorphism of the anterior commissure and interthalamic adhesion of the human brain. J Comp Neurol 312(1):97–104. https://doi.org/10.1002/cne.903120108CrossRefPubMed

Birkl C, Langkammer C, Golob-Schwarzl N, Leoni M, Haybaeck J, Goessler W, Fazekas F, Ropele S (2016) Effects of formalin fixation and temperature on MR relaxation times in the human brain. NMR Biomed 29(4):458–465. https://doi.org/10.1002/nbm.3477CrossRefPubMed

Birnbaum R, Parodi S, Donarini G, Meccariello G, Fulcheri E, Paladini D (2018) The third ventricle of the human fetal brain: Normative data and pathologic correlation. A 3D transvaginal neurosonography study. Pren Diagn 38(9):664–672. https://doi.org/10.1002/pd.5292CrossRef

Borghei A, Cothran T, Brahimaj B, Sani S (2020) Role of interthalamic adhesion in human neurocognitive processing. Brain Struct Funct 225(3):985–993. https://doi.org/10.1007/s00429-020-02050-5CrossRefPubMed

Ceyhan M, Adapınar B, Aksaray G, Ozdemir F, Colak E (2008) Absence and size of interthalamic adhesion in patients with schizophrenia and bipolar disorder. Acta Neuropsychiatrica 20(4):193–198. https://doi.org/10.1111/j.1601-5215.2008.00296.xCrossRefPubMed

Damle NR, Ikuta T, John M, Peters BD, DeRosse P, Malhotra AK, Szeszko PR (2017) Relationship among interthalamic adhesion size, thalamic anatomy and neuropsychological functions in healthy volunteers. Brain Struct Funct 222(5):2183–2192. https://doi.org/10.1007/s00429-016-1334-6CrossRefPubMed

de Souza Crippa JA, Zuardi AW, Busatto GF, Sanches RF, Santos AC, Araújo D, Amaro E, Hallak JE, Ng V, McGuire PK (2006) Cavum septum pellucidum and adhesio interthalamica in schizophrenia: an MRI study. Eur Psych 21(5):291–299. https://doi.org/10.1016/j.eurpsy.2005.09.010CrossRef

Erbağci H, Yildirim H, Herken H, Gümüşburun E (2002) A magnetic resonance imaging study of the adhesio interthalamica in schizophrenia. Schizophr Res 55(1–2):89–92. https://doi.org/10.1016/s0920-9964(01)00199-2CrossRefPubMed

Ettinger U, Picchioni M, Landau S, Matsumoto K, van Haren NE, Marshall N, Hall MH, Schulze K, Toulopoulou T, Davies N, Ribchester T, McGuire PK, Murray RM (2007) Magnetic resonance imaging of the thalamus and adhesio interthalamica in twins with schizophrenia. Arch Gen Psychiatry 64(4):401–409. https://doi.org/10.1001/archpsyc.64.4.401CrossRefPubMed

Ferraz De Macedo F (1889) Note sur l'absence de la commissure grise du troisième ventricule et les particularités psychiques concomitantes (suite). Bulletins et Mémoires de la Société d'Anthropologie de Paris:541–548

Haghir H, Mokhber N, Azarpazhooh MR, Haghighi MB, Radmard M (2013) A magnetic resonance imaging study of adhesio interthalamica in clinical subtypes of schizophrenia. Indian J Psychiatry 55(2):135–139. https://doi.org/10.4103/0019-5545.111450CrossRefPubMedPubMedCentral

Ingalhalikar M, Smith A, Parker D, Satterthwaite TD, Elliott MA, Ruparel K, Hakonarson H, Gur RE, Gur RC, Verma R (2014) Sex differences in the structural connectome of the human brain. Proc Natl Acad Sci USA 111(2):823–828. https://doi.org/10.1073/pnas.1316909110CrossRefPubMed

Jordan WH, Young JK, Hyten MJ, Hall DG (2011) Preparation and analysis of the central nervous system. Toxicol Pathol 39(1):58–65. https://doi.org/10.1177/0192623310391480CrossRefPubMed

Kochanski RB, Dawe R, Kocak M, Sani S (2018) Identification of stria medullaris fibers in the interthalamic adhesion using diffusion tensor imaging. World Neurosurg 112:e497–e504. https://doi.org/10.1016/j.wneu.2018.01.066CrossRefPubMed

Landin-Romero R, Amann BL, Sarró S, Guerrero-Pedraza A, Vicens V, Rodriguez-Cano E, Vieta E, Salvador R, Pomarol-Clotet E, Radua J (2016) Midline brain abnormalities across psychotic and mood disorders. Schizophr Bull 42(1):229–238. https://doi.org/10.1093/schbul/sbv097CrossRefPubMed

Lansdell H, Davie JC (1972) Interthalamic adhesion: possible relation to intelligence. Neuropsychologia 10(2):207–210. https://doi.org/10.1016/0028-3932(72)90061-9CrossRefPubMed

Malobabić S, Puskas L, Blagotić M (1987) Size and position of the human adhaesio interthalamica. Gegenbaurs Morphol Jahrb 133(1):175–180PubMed

Meisenzahl EM, Frodl T, Zetzsche T, Leinsinger G, Heiss D, Maag K, Hegerl U, Hahn K, Möller HJ (2000) Adhesio interthalamica in male patients with schizophrenia. Am J Psychiatry 157(5):823–825. https://doi.org/10.1176/appi.ajp.157.5.823CrossRefPubMed

Meisenzahl EM, Frodl T, Zetzsche T, Leinsinger G, Maag K, Hegerl U, Hahn K, Möller HJ (2002) Investigation of a possible diencephalic pathology in schizophrenia. Psychiatry Res 115(3):127–135. https://doi.org/10.1016/s0925-4927(02)00044-6CrossRefPubMed

Nopoulos PC, Rideout D, Crespo-Facorro B, Andreasen NC (2001) Sex differences in the absence of interthalamic adhesion in patients with schizophrenia versus healthy controls. Schizophr Res 48(2–3):177–185. https://doi.org/10.1016/s0920-9964(00)00067-0CrossRefPubMed

Pavlović MN, Jovanović ID, Ugrenović SZ, Kostić AV, Kundalić BK, Stojanović VR, Vlajković S, Trandafilović MM, Čukuranović-Kokoris JR, Antić MM (2020) Position and size of interthalamic adhesion in Serbian brains. Folia Morphol 79(1):21–27. https://doi.org/10.5603/FM.a2019.0046CrossRef

Rosales RK, Lemay MJ, Yakovley PI (1968) The development and involution of interthalamic adhesion with regard to age and sex. J Neuropathol Exp Neurol 27(1):166PubMed

Samra KA, Cooper IS (1968) Radiology of the interthalamic adhesion. Radiology 91(6):1124–1128. https://doi.org/10.1148/91.6.1124CrossRefPubMed

Scarabino T, Nemore F, Giannatempo GM, Bertolino A, Di Salle F, Salvolini U (2003) 3.0 T magnetic resonance in neuroradiology. Eur J Radiol 48(2):154–164. https://doi.org/10.1016/j.ejrad.2003.08.008CrossRefPubMed

Sen F, Ulubay H, Ozeksi P, Sargon M, Tascioglu AB (2005) Morphometric measurements of the thalamus and interthalamic adhesion by MR imaging. Neuroanatomy 4:10–12

Severino M, Righini A, Tortora D, Pinelli L, Parazzini C, Morana G, Accorsi P, Capra V, Paladini D, Rossi A (2017) MR Imaging diagnosis of diencephalic-mesencephalic junction dysplasia in fetuses with developmental ventriculomegaly. AJNR Am J Neuroradiol 38(8):1643–1646. https://doi.org/10.3174/ajnr.A5245CrossRefPubMedPubMedCentral

Shimizu M, Fujiwara H, Hirao K, Namiki C, Fukuyama H, Hayashi T, Murai T (2008) Structural abnormalities of the adhesio interthalamica andmediodorsal nuclei of the thalamus in schizophrenia. Schizophr Res 101(1–3):331–338. https://doi.org/10.1016/j.schres.2007.12.486CrossRefPubMed

Snyder PJ, Bogerts B, Wu H, Bilder RM, Deoras KS, Lieberman JA (1998) Absence of the adhesio interthalamica as a marker of early developmental neuropathology in schizophrenia: an MRI and postmortem histologic study. J Neuroimag 8(3):159–163. https://doi.org/10.1111/jon199883159CrossRef

Springer E, Dymerska B, Cardoso PL, Robinson SD, Weisstanner C, Wiest R, Schmitt B, Trattnig S (2016) Comparison of routine brain imaging at 3 T and 7 T. Invest Radiol 51(8):469–482. https://doi.org/10.1097/rli.0000000000000256CrossRefPubMedPubMedCentral

Takahashi T, Suzuki M, Nakamura K, Tanino R, Zhou SY, Hagino H, Niu L, Kawasaki Y, Seto H, Kurachi M (2008a) Association between absence of the adhesio interthalamica and amygdala volume in schizophrenia. Psychiatry Res 162(2):101–111. https://doi.org/10.1016/j.pscychresns.2007.04.005CrossRefPubMed

Takahashi T, Suzuki M, Zhou SY, Nakamura K, Tanino R, Kawasaki Y, Seal ML, Seto H, Kurachi M (2008b) Prevalence and length of the adhesio interthalamica in schizophrenia spectrum disorders. Psychiatry Res 164(1):90–94. https://doi.org/10.1016/j.pscychresns.2008.03.001CrossRefPubMed

Takahashi T, Yücel M, Yung AR, Wood SJ, Phillips LJ, Berger GE, Ang A, Soulsby B, McGorry PD, Suzuki M, Velakoulis D, Pantelis C (2008c) Adhesio interthalamica in individuals at high-risk for developing psychosis and patients with psychotic disorders. Prog Neuropsychopharmacol Biol Psychiatry 32(7):1708–1714. https://doi.org/10.1016/j.pnpbp.2008.07.007CrossRefPubMed

Takahashi T, Chanen AM, Wood SJ, Walterfang M, Harding IH, Yücel M, Nakamura K, McGorry PD, Suzuki M, Velakoulis D, Pantelis C (2009a) Midline brain structures in teenagers with first-presentation borderline personality disorder. Prog Neuropsychopharmacol Biol Psychiatry 33(5):842–846. https://doi.org/10.1016/j.pnpbp.2009.03.035CrossRefPubMed

Takahashi T, Yücel M, Lorenzetti V, Nakamura K, Whittle S, Walterfang M, Suzuki M, Pantelis C, Allen NB (2009b) Midline brain structures in patients with current and remitted major depression. Prog Neuropsychopharmacol Biol Psychiatry 33(6):1058–1063. https://doi.org/10.1016/j.pnpbp.2009.05.020CrossRefPubMed

Takahashi T, Malhi GS, Wood SJ, Yücel M, Walterfang M, Nakamura K, Suzuki M, Pantelis C (2010) Midline brain abnormalities in established bipolar affective disorder. J Affect Disord 122(3):301–305. https://doi.org/10.1016/j.jad.2009.09.003CrossRefPubMed

Trzesniak C, Schaufelberger MS, Duran FL, Santos LC, Rosa PG, McGuire PK, Murray RM, Scazufca M, Menezes PR, Hallak JE, Crippa JA, Busatto GF (2012) Longitudinal follow-up of cavum septum pellucidum and adhesio interthalamica alterations in first-episode psychosis: apopulation-based MRI study. Psychol Med 42(12):2523–2534. https://doi.org/10.1017/s0033291712000839CrossRefPubMed

Trzesniak C, Linares IM, Coimbra ÉR, Júnior AV, Velasco TR, Santos AC, Hallak JE, Sakamoto AC, Busatto GF, Crippa JA (2016) Adhesio interthalamica and cavum septum pellucidum in mesial temporal lobe epilepsy. Brain Imag Behav 10(3):849–856. https://doi.org/10.1007/s11682-015-9461-xCrossRef

Tyan YS, Liao JR, Shen CY, Lin YC, Weng JC (2017) Gender differences in the structural connectome of the teenage brain revealed by generalized q-sampling MRI. NeuroImage Clin 15:376–382. https://doi.org/10.1016/j.nicl.2017.05.014CrossRefPubMedPubMedCentral

Whitehead MT, Najim N (2020) Thalamic Massa Intermedia in Children with and without Midline Brain Malformations. AJNR Am Jneuroradiol 41(4):729–735. https://doi.org/10.3174/ajnr.A6446CrossRef

Yasaka K, Akai H, Kunimatsu A, Kiryu S, Abe O (2019) Factors associated with the size of the adhesio interthalamica based on 3.0 T magnetic resonance images. Acta Radiol 60(1):113–119. https://doi.org/10.1177/0284185118774952CrossRefPubMed

Zijlmans M, de Kort GA, Witkamp TD, Huiskamp GM, Seppenwoolde JH, van Huffelen AC, Leijten FS (2009) 3T versus 1.5T phased-array MRI in the presurgical work-up of patients with partial epilepsy of uncertain focus. J Magn Reson Imag 30(2):256–262. https://doi.org/10.1002/jmri.21811CrossRef

Titel: Prevalence of the interthalamic adhesion in the human brain: a review of literature
verfasst von: Andrew K. Wong
Daniel I. Wolfson
Alireza Borghei
Sepehr Sani
Publikationsdatum: 12.07.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: Brain Structure and Function / Ausgabe 8/2021
Print ISSN: 1863-2653
Elektronische ISSN: 1863-2661
DOI: https://doi.org/10.1007/s00429-021-02287-8

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