Skip to main content
main-content

01.12.2014 | Ausgabe 6/2014

Prevention Science 6/2014

Preventing Internalizing Symptoms Among Hispanic Adolescents: A Synthesis Across Familias Unidas Trials

Zeitschrift:
Prevention Science > Ausgabe 6/2014
Autoren:
Tatiana Perrino, Hilda Pantin, Guillermo Prado, Shi Huang, Ahnalee Brincks, George Howe, William Beardslee, Irwin Sandler, C. Hendricks Brown
Wichtige Hinweise

Author Note

Tatiana Perrino, Hilda Pantin, Guillermo Prado, Shi Huang, and Ahnalee Brincks are at the Miller School of Medicine, University of Miami in Miami, FL. George Howe is at George Washington University in Washington, DC. William Beardslee is at Children’s Hospital-Boston and Harvard University-Cambridge, MA. Irwin Sandler is at Arizona State University in Tempe, AZ. C Hendricks Brown is at the Feinberg School of Medicine, Northwestern University in Chicago, IL.
This work was supported by the following grants: National Institute of Mental Health Grant No. R01MH040859 (C. Hendricks Brown, PI); National Institute of Mental Health Grant No. R01MH61143 (Jose Szapocznik, PI); National Institute on Drug Abuse Grant No.R01DA017462 (Hilda Pantin, PI); and National Institute on Drug Abuse Grant No R01DA025894 (Guillermo Prado, PI).

Abstract

Studies document that there are efficacious interventions to prevent adolescent depression and internalizing symptoms, including several family-focused interventions. Questions remain about for whom interventions work (moderation) and by what mechanisms they work (mediation) to prevent internalizing symptoms. Unfortunately, single trials are often underpowered to address moderation and mediation, an issue addressed in this paper. This synthesis study combined individual-level, longitudinal data from 721 adolescents across 3 randomized clinical trials of Familias Unidas, a family-focused prevention intervention for Hispanic youth. Using integrative data analysis (IDA) methods applied to trials, the study examined intervention moderation and mediation effects on internalizing symptoms. Baseline internalizing symptoms were a significant moderator of the intervention’s effects on internalizing symptoms, while baseline externalizing symptoms did not moderate intervention effects. Baseline parent–adolescent communication, a modifiable risk factor and hypothesized mechanism by which the intervention works, significantly moderated the intervention’s effects. Specifically, the intervention was more efficacious in its impact on internalizing symptoms for youth with lower initial levels of parent–adolescent communication compared to those with higher communication levels. Moderated mediation analyses showed that parent–adolescent communication changes mediated the intervention’s effects on internalizing symptoms, with stronger effects for those with poorer baseline communication. Results suggest a potential benefit of identifying youth risks prior to interventions, and targeting specific modifiable mediators that lead to reductions of internalizing problems of adolescents. Findings also highlight advantages of utilizing data from combined trials and IDA for examining intervention moderators and mediators.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 6/2014

Prevention Science 6/2014 Zur Ausgabe