nach oben

European Journal of Applied Physiology

Erschienen in:

01.09.2006 | Original Article

Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress

verfasst von: Hsueh-Kuan Lu, Chin-Cheng Hsieh, Jen-Jung Hsu, Yuh-Kuan Yang, Hong-Nong Chou

Erschienen in: European Journal of Applied Physiology | Ausgabe 2/2006

Einloggen, um Zugang zu erhalten

Abstract

The effects of spirulina supplementation on preventing skeletal muscle damage on untrained human beings were examined. Sixteen students volunteered to take Spirulina platensis in addition to their normal diet for 3-weeks. Blood samples were taken after finishing the Bruce incremental treadmill exercise before and after treatment. The results showed that plasma concentrations of malondialdehyde (MDA) were significantly decreased after supplementation with spirulina (P < 0.05). The activity of blood superoxide dismutase (SOD) was significantly raised after supplementation with spirulina or soy protein (P < 0.05). Both of the blood glutathione peroxidaes (GP_x) and lactate dehydrogenase (LDH) levels were significantly different between spirulina and soy protein supplementation by an ANCOVA analysis (P < 0.05). In addition, the lactate (LA) concentration was higher and the time to exhaustion (TE) was significantly extended in the spirulina trail (P < 0.05). These results suggest that ingestion of S. platensis showed preventive effect of the skeletal muscle damage and that probably led to postponement of the time of exhaustion during the all-out exercise.

Al-Batshan HA, Al-Mufarrej SI, Al-Homaidan AA, Qureshi MA (2001) Enhancement of chicken macrophage phagocytic function and nitrite production by dietary Spirulina platensis. Immunopharm Immunotox 2(23):281–289CrossRef

Alessio HM, Hagerman AE, Fulkerson BK, Ambrose J, Rice RE, Wiley RL (2000) Generation of reactive oxygen species after exhaustive aerobic and isometric exercise. Med Sci Sports Exerc 32(9):1576–1581PubMedCrossRef

Ashmaig ME, Starkey BJ, Ziada AM, Amro AA, Sobki SH, Ferns GA (2001) Changes in serum concentrations of markers of myocardial injury following treadmill exercise testing in patients with suspected ischemic heart disease. Int Med J Exp Clin Res 7(1):54–57

Bagchi D, Bagchi M, Stohs SJ, Das DK, Ray SD, Kuszynski CA, Joshi SS, Pruess HG (2000) Free radicals and grape seed proanthocyanidin extract: importance in humanhealth and disease prevention. Toxicology 148(2–3):187–197PubMedCrossRef

Beaton LJ, Allan DA, Tarnopolsky MA, Tiidus PM, Phillips SM (2002) Contraction-induced muscle damage is unaffected by vitamin E supplementation. Med Sci Sports Exerc 34(5):798–805PubMedCrossRef

Belay A, Kato T, Ota Y (1996) Spirulina (Arthrospira): potential application as an animal feed supplement. J Appl Phycol 4–5(8):303–311CrossRef

Bruce RA (1972) Multi-stage treadmill tests of maximal and submaximal exercise. In: American Heart Association (ed)Exercise testing and training of apparently healthy individuals: a handbook for physicians, New York, pp 32–34

Chen TC, Hsieh SS (2001) Effects of a 7-day eccentric training period on muscle damage and inflammation. Med Sci Sports Exerc 33(10):1732–1738PubMedCrossRef

Chen YJ, Serfass RC, Apple FS (2000) Loss of myocardial CK-MB into the circulation following 3.5 hours of swimming in a rat model. Int J Sports Med 21(8):561–565PubMedCrossRef

Chien YH, Pan CH, Hunter B (2003) The resistance to physical stress by Penaeus monodon juveniles fed diets supplemented with astaxanthin. Aquaculture 216(1–4):177–192CrossRef

Farooq SM, Asokan D, Sakthivel R, Kalaiselvi P, Varalakshmi P (2004) Salubrious effect of C-phycocyanin against oxalate-mediated renal cell injury. Clin Chim Acta 348(1–2):199–205PubMedCrossRef

Fox RD (1996) Spirulina, production and potential. Aix-en-Provence, Edisud, pp 9–232

Goldfarb AH (1995) Nutritional anti-oxidants as therapeutic and preventive modalities in exercise—induced muscle damage. Can J Appl Physiol 24(3):249–266

Gireesh T, Nair PP, Sudhakaran PR (2004) Studies on the bioavailability of the provitamin A carotenoid, beta-carotene, using human exfoliated colonic epithelial cells. Br J Nutr 92(2):241–245PubMedCrossRef

Hayashi K, Hayashi T, Kojima I (1996) A natural sulfated polysaccharide, calcium spirulan, isolated from Spirulina platensis: in vitro and ex vivo evaluation of anti-herpes simplex virus and anti-human immunodeficiency virus activities. AIDS Res Human Retrovir 15(12):1463–1471CrossRef

Hayashi O, Hirahashi T, Katoh T, Miyajima H, Hirano T, Okuwaki Y (1998) Class specific influence of dietary Spirulina platensis on antibody production in mice. J Nutr Sci Vitaminol 6(44):841–851

Huang LX, Lu XC, Yang B, Lin JS (2000) Effects of Spirulina platensis on exercise-induced muscle damage in rats. Sport Sci 20(2):58–59

Jackson MJ (1998) Free radical mechanisms in exercise-related muscle damage. In: Reznick AZ, Packer L, Sen CK, Holloszy JO, Jackson MJ (eds) Oxidative stress in skeletal muscle. Birkhauser Verlag, Basel, pp 75–86

Jain SK (1988) Evidence for membrane lipid peroxidation during the in vivo aging of human erythrocytes. Biochim Biophys Acta 937:205–210PubMedCrossRef

Kanter MM, Williamhe MH (1995) Anti-oxydants, carnitine and choline as putative ergogenic aids. Int J Sports Nutr 5(2):120–131

Langberg H, Skovgaard D, Asp S, Kjaer M (2000) Time pattern of exercise induced changes in type I collagen turnover after prolonged endurance exercise in humans. Calcif Tissue Int 67(1):41–44PubMedCrossRef

Mani UV, Desai S, Iyer U (2000) Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. J Nutra Func Med Foods 3(2):25–32CrossRef

Mastaloudis A, Leonard SW, Traber MG (2001) Oxidative stress in athletes during extreme endurance exercise. Free Radic Biol Med 31:911–922PubMedCrossRef

Mathew B, Rengaswamy S, Nair PP, Varghese C, Thara S, Amma BP, Amma NS, Nair MK (1995) Evaluation of chemoprevention of oral cancer with Spirulina fusiformis. Nutr Cancer 2(24):197–202CrossRef

Matuschek E, Svanberg U (2002) Oxidation of polyphenols and the effect of in vitro iron accessibility in a model food system. J Food Sci 67(1):420–424CrossRef

Micheletti A, Rossi R, Rufini S (2001) Zinc status in athletes: relation to diet and exercise. Sports Med 31(8):577–582PubMedCrossRef

Nosaka K, Newton M, Sacco P (2002) Muscle damage and soreness after endurance exercise of the elbow flexors. Med Sci Sports Exerc 34(6):920–926PubMedCrossRef

Overgaard K, Lindstrom T, Ingemann-Hansen T, Clausen T (2002) Membrane leakage and increased content of Na+ -K+ pumps and Ca2+ in human muscle after a 100-km run. J Appl Physiol: Resp Envir Exerc Physiol 92(5):1891–1898

Paredes-Carbajal MC, Torres-Duran PV, Diaz-Zagoya JC, Mascher D, Juarez-Oropeza MA (2001) Effects of the ethanolic extract of Spirulina maxima on endothelium dependent vasomotor responses of rat aortic rings. J Ethnopharm 1(75):37–44CrossRef

Powers SK, Deruisseau KC, Quindry J, Hamilton KL (2004) Dietary anti-oxidants and exercise. J Sports Sci 22:81–94PubMedCrossRef

Rodriguez-Hernandez A, Ble-Castillo JL, Juarez-Oropeza MA, Diaz-Zagoya JC (2001) Spirulina maxima prevents fatty liver formation in CD-1 male and female mice with experimental diabetes. Life Sci 9(69):1029–1037CrossRef

Song Y, Igawa S, Horii A (1996) Anti-oxidant enzymes response to endurance exercise training and dietary proteins in rat skeletal muscle and liver. Appl Human Sci 15(5):219–525PubMedCrossRef

Stuewe SR, Gwirtz PA, Mallet RT (2001) Exercise training increases creatine kinase capacity in canine myocardium. Med Sci Sports Exerc 33(1):92–98PubMed

Svensson M, Malm C, Tonkonogi M, Ekblom B, Sjodin B, Sahlin K (1999) Effect of Q10 supplementation on tissue Q10 levels and adenine nucleotide catabolism during high-intensity exercise. Int J Sports Nutr 9(2):166–180

Tanticharoen M, Reungjitchachawali M, Boonag B, Vonktaveesuk P, Vonshak A, Cohen Z (1994) Optimization of gamma-linolenic acid (GLA) production in Spirulina platensis. J Appl Phycol 3(6):295–300CrossRef

Uliyar M, Alefia S, Uma I, Panam P (2000) The effect of Spirulina supplementation on blood hemoglobin levels of anaemic adult girls. J Food Sci Technol (Mysore) 6(37):642–644

Vonshak A (1997) Spirulina platensis (Arthrospira): physiology, cell-biology, and biotechnology, Taylor and Francis, London, pp 1–233

Wu GX, Feng LS, Feng WQ (2000) Effects of co-lecithin on serum testosterone and cortisone of athletes. Sport Sci 20(4):53–55

Zhang YF, Liu XC (1999) Study on the anti-fatigue effect of polysaccharide and polysaccharide-protein from Spirulina platensis. Mar Sci Bull/Haiyang Tongbao Tianjin 18(3):89–91

Titel: Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress
verfasst von: Hsueh-Kuan Lu
Chin-Cheng Hsieh
Jen-Jung Hsu
Yuh-Kuan Yang
Hong-Nong Chou
Publikationsdatum: 01.09.2006
Verlag: Springer-Verlag
Erschienen in: European Journal of Applied Physiology / Ausgabe 2/2006
Print ISSN: 1439-6319
Elektronische ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-006-0263-0

Neu im Fachgebiet Arbeitsmedizin

Elterliches Belastungserleben, Unaufmerksamkeits‑/Hyperaktivitätssymptome und elternberichtete ADHS bei Kindern und Jugendlichen: Ergebnisse aus der KiGGS-Studie

Open Access ADHS Leitthema

Die Aufmerksamkeitsdefizit‑/Hyperaktivitätsstörung (ADHS) ist eine der häufigsten psychischen Störungen im Kindes- und Jugendalter [ 1 ]. In Deutschland beträgt die Prävalenz einer elternberichteten ADHS-Diagnose bei Kindern und Jugendlichen 4,4 % …

Substanzkonsum und Nutzung von sozialen Medien, Computerspielen und Glücksspielen unter Auszubildenden an beruflichen Schulen

Open Access Leitthema

Die Begrenzung von Schäden durch Substanzkonsum und andere abhängige Verhaltensweisen von Jugendlichen und jungen Erwachsenen ist ein wichtiges Anliegen der öffentlichen Gesundheit. Der Übergang von der Adoleszenz zum jungen Erwachsenenalter ist …

Berufsbelastung und Stressbewältigung von weiblichen und männlichen Auszubildenden

Leitthema

In der Öffentlichkeit wird die berufliche Ausbildung oftmals unter ökonomischen Gesichtspunkten diskutiert: Mit den geburtenstarken Jahrgängen gehen erfahrene Fachkräfte in Rente und von nachfolgenden Generationen rücken zu wenige Arbeitskräfte …

Rauschtrinken in der frühen Adoleszenz

COVID-19 Leitthema

Alkohol ist in Deutschland die mit Abstand am häufigsten konsumierte psychoaktive Substanz. Mehr als 2 Drittel aller Erwachsenen im Alter von 18 bis 64 Jahren (70,5 %) hat 2021 in den letzten 30 Tagen Alkohol konsumiert [ 1 ]. Von diesen …

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2006

Indicators of maximal hiking performance in Laser sailors

Prolonged exercise does not cause lymphocyte DNA damage or increased apoptosis in well-trained endurance athletes

Effect of equitation training on health and physical fitness of college females

Late neural adaptations to electrostimulation resistance training of the plantar flexor muscles

Critical velocity during continuous and intermittent exercises in children

Effect of single-leg resistance exercise on regional arterial stiffness

Neu im Fachgebiet Arbeitsmedizin

Elterliches Belastungserleben, Unaufmerksamkeits‑/Hyperaktivitätssymptome und elternberichtete ADHS bei Kindern und Jugendlichen: Ergebnisse aus der KiGGS-Studie

Substanzkonsum und Nutzung von sozialen Medien, Computerspielen und Glücksspielen unter Auszubildenden an beruflichen Schulen

Berufsbelastung und Stressbewältigung von weiblichen und männlichen Auszubildenden

Rauschtrinken in der frühen Adoleszenz