The online version of this article (doi:10.1186/1477-7819-10-33) contains supplementary material, which is available to authorized users.
The authors declare that they have no competing interests.
JL wrote the initial draft. ZH and FJ participated in the pathology. YW, YH and CW are surgeons of the patient and help to collect clinical materials. QC conceived of the study design and helped to draft the manuscript. All authors read and approved the final manuscript.
Clear cell carcinoma of the bladder is a rare tumor of the bladder. There are few reports available on this rare disease, and no cases with recurrence were reported. Here we present a case of 68-year-old woman with primary clear cell carcinoma of the bladder, who underwent repeat TUR-BT and tumor recurrence. We also reviewed the previous treatments and prognoses in previous case reports and evaluate the proper treatment for this disease. Once the diagnosis is determined, the radical surgery should be recommended. The recurrence is not prevented based on post-TUR intravesical therapy.
Authors’ original file for figure 112957_2011_960_MOESM1_ESM.jpeg
Authors’ original file for figure 212957_2011_960_MOESM2_ESM.jpeg
Authors’ original file for figure 312957_2011_960_MOESM3_ESM.jpeg
Authors’ original file for figure 412957_2011_960_MOESM4_ESM.jpeg
Authors’ original file for figure 512957_2011_960_MOESM5_ESM.jpeg
Authors’ original file for figure 612957_2011_960_MOESM6_ESM.jpeg
Fleshner NE, Herr HW, Stewart AK, Murphy GP, Mettlin C, Menck HR: The National Cancer Data Base report on bladder carcinoma. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer. 1996, 78 (7): 1505-13. 10.1002/(SICI)1097-0142(19961001)78:7<1505::AID-CNCR19>3.0.CO;2-3. CrossRefPubMed
Kantor AF, Hartge P, Hoover RN, Fraumeni JF: Epidemiological characteristics of squamous cell carcinoma and adenocarcinoma of the bladder. Cancer Res. 1988, 48 (13): 3853-5. PubMed
Eble JN, Epstein JI, Seternhenn IA: World Health Organization Classification of Tumours Pathology and Genetics, Tumours of the Urinary System and Male Genital track. 2004, Lyon: IARC Press, 128-132.
Dow JA, Young JD: Mesonephric adenocarcinoma of the bladder. J Urol. 1968, 100 (4): 466-9. PubMed
Chor PJ, Gaum LD, Young RH: Clear cell adenocarcinoma of the urinary bladder: report of a case of probable mullerian origin. Mod Pathol. 1993, 6 (2): 225-8. PubMed
Ito K, Yamanaka H, Ichinose Y, Kurihara J: A case of adenocarcinoma with clear cell carcinoma of the bladder. Hinyokika Kiyo. 1999, 45 (9): 637-40. PubMed
Mai KT, Yazdi HM, Perkins DG, Morash C, Green J: Multicentric clear cell adenocarcinoma in the urinary bladder and the urethral diverticulum: evidence of origin of clear cell adenocarcinoma of the female lower urinary tract from Mullerian duct remnants. Histopathology. 2000, 36 (4): 380-2. 10.1046/j.1365-2559.2000.0855e.x. CrossRefPubMed
Honda N, Yamada Y, Nanaura H, Fukatsu H, Nonomura H, Hatano Y: Mesonephric adenocarcinoma of the urinary bladder: a case report. Hinyokika Kiyo. 2000, 46 (1): 27-31. PubMed
Sun K, Huan Y, Unger PD: Clear cell adenocarcinoma of urinary bladder and urethra: another urinary tract lesion immunoreactive for P504S. Arch Pathol Lab Med. 2008, 132 (9): 1417-22. PubMed
Oliva E, Amin MB, Jimenez R, Young RH: Clear cell carcinoma of the urinary bladder: a report and comparison of four tumors of mullerian origin and nine of probable urothelial origin with discussion of histogenesis and diagnostic problems. Am J Surg Pathol. 2002, 26 (2): 190-7. 10.1097/00000478-200202000-00005. CrossRefPubMed
Balat O, Kudelka AP, Edwards CL, Silva E, Kavanagh JJ: Malignant transformation in endometriosis of the urinary bladder: case report of clear cell adenocarcinoma. Eur J Gynaecol Oncol. 1996, 17 (1): 13-6. PubMed
- Primary clear cell adenocarcinoma of the bladder with recurrence: a case report and literature review
- BioMed Central
Neu im Fachgebiet Chirurgie
Mail Icon II