The online version of this article (doi:10.1186/1477-7819-10-189) contains supplementary material, which is available to authorized users.
Xu-Dong Yao, Ya-Ping Hong contributed equally to this work.
The authors declare that they have no competing interests.
XDY and HYP conceived the concept for the study, participated in drafting the manuscript, and conducted a critical review. Both authors contributed equally to this work. DWY participated in revising the manuscript critically for important intellectual content. CFW prepared the histological figures. All authors read and approved the final manuscript.
Yolk sac tumor (endodermal sinus tumor) is a rare malignant germ cell tumor arising in the testis or ovary. Extragonadal yolk sac tumor is even rarer and has only been described in case reports. Due to the rarity of the tumors, the appropriately optimal treatment remains unclear. We report a case of yolk sac tumor in the seminal vesicle.
A 38-year-old Asian male presented with gross hematuria and hemospermia. Transrectal ultrasound scan showed a solid mass in the left seminal vesicle and the scrotal sonography showed no abnormalities. Bilateral seminal vesicles were resected, and histopathological examination showed a typical pattern of yolk sac tumor (YST). The patient responded poorly to comprehensive treatment of radiotherapy, chemotherapy and surgeries, developed systemic multiple metastases, and died of cachexia one and half years after diagnosis.
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- Primary yolk sac tumor of seminal vesicle: a case report and literature review
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