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Surgery Today

20.06.2016 | Original Article

Prognostic implications of preoperative chronic kidney disease and anemia in patients undergoing coronary artery bypass graft surgery

verfasst von: Takuya Ogami, Yuya Matsue, Ryo Kawasumi, Hiroaki Tanabe

Erschienen in: Surgery Today | Ausgabe 2/2017

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Abstract

Purpose

Chronic kidney disease (CKD) and anemia are independent preoperative risk factors for coronary artery bypass graft (CABG) surgery. We evaluated the implications of the coexistence of these two factors and their associated prognosis for CABG surgery.

Methods

We analyzed, retrospectively, consecutive patients who underwent elective CABG surgery between 2004 and 2014. The patients were classified into four groups depending on the presence or absence of preoperative CKD and anemia. We assessed the major adverse cardiac and cerebrovascular event (MACCE), defined as composite outcomes of cardio- and cerebrovascular death, revascularization through surgery or percutaneous intervention, hospitalization for congestive heart failure, and cerebral infarction.

Results

The study population consisted of 510 patients (73 % male; median age 71 years old), followed up for a median period of 2.8 years. Multivariate analysis indicated that neither the CKD/no-anemia group [hazard ratio (HR) 0.98, 95 % confidence interval (CI) 0.39–2.51, P = 0.973] nor the no-CKD/anemia group (HR 1.20, 95 % CI 0.69–2.09, P = 0.512) had significantly poorer prognoses than the no-CKD/no-anemia group. However, the CKD/anemia group had a significantly higher risk of a MACCE (HR 2.01, 95 % CI 1.01–3.98, P = 0.046).

Conclusion

The presence of both CKD and anemia in patients undergoing CABG for coronary artery disease is synergistically associated with a worse outcome.
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Metadaten
Titel
Prognostic implications of preoperative chronic kidney disease and anemia in patients undergoing coronary artery bypass graft surgery
verfasst von
Takuya Ogami
Yuya Matsue
Ryo Kawasumi
Hiroaki Tanabe
Publikationsdatum
20.06.2016
Verlag
Springer Japan
Erschienen in
Surgery Today / Ausgabe 2/2017
Print ISSN: 0941-1291
Elektronische ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-016-1368-7

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