nach oben

Current Infectious Disease Reports

Erschienen in:

01.08.2011

Prosthetic Vascular Graft Infections: A Contemporary Approach to Diagnosis and Management

verfasst von: Avish Nagpal, Muhammad R. Sohail

Erschienen in: Current Infectious Disease Reports | Ausgabe 4/2011

Einloggen, um Zugang zu erhalten

Abstract

Improvements in manufacturing and implantation techniques, coupled with an increasing prevalence of atherosclerosis in an aging population, have led to increased utilization of prosthetic vascular grafts. The infection rates of vascular grafts are low. However, when they do occur, high rates of morbidity and mortality can be expected. The purpose of this article is to review the published literature regarding epidemiology, risk factors, pathogenesis, and clinical manifestations of prosthetic vascular graft infections. Moreover, we provide a practical approach to the diagnosis and management of these complicated infections based on empirically grounded evidence.

Darouiche RO. Treatment of infections associated with surgical implants. N Engl J Med. 2004;350:1422–9.PubMedCrossRef

Antonios VS, Baddour LM. Intra-arterial device infections. Curr Infect Dis Rep. 2004;6:263–9.PubMedCrossRef

Seeger JM, Pretus HA, Welborn MB, et al. Long-term outcome after treatment of aortic graft infection with staged extra-anatomic bypass grafting and aortic graft removal. J Vasc Surg. 2000;32:451–9. discussion 460–451.PubMedCrossRef

Mussa FF, Hedayati N, Zhou W, et al. Prevention and treatment of aortic graft infection. Expert Rev Anti Infect Ther. 2007;5:305–15.PubMedCrossRef

Quinones-Baldrich WJ, Hernandez JJ, Moore WS. Long-term results following surgical management of aortic graft infection. Arch Surg. 1991;126:507–11.PubMed

Seeger JM. Management of patients with prosthetic vascular graft infection. Am Surg. 2000;66:166–77.PubMed

Chaudhary R, Simmons RL. Pathogenesis of vascular graft infections. J Vasc Surg. 1991;13:755–6.PubMed

Antonios VS, Noel AA, Steckelberg JM, et al. Prosthetic vascular graft infection: a risk factor analysis using a case-control study. J Infect. 2006;53:49–55.PubMedCrossRef

Baddour LM, Bettmann MA, Bolger AF, et al. Nonvalvular cardiovascular device-related infections. Clin Infect Dis. 2004;38:1128–30.PubMedCrossRef

10.

Cramton SE, Gerke C, Schnell NF, et al. The intercellular adhesion (ica) locus is present in Staphylococcus aureus and is required for biofilm formation. Infect Immun. 1999;67:5427–33.PubMed

11.

Heilmann C, Schweitzer O, Gerke C, et al. Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis. Mol Microbiol. 1996;20:1083–91.PubMedCrossRef

12.

Wann ER, Gurusiddappa S, Höök M. The Fibronectin-binding MSCRAMM FnbpA of Staphylococcus aureus Is a Bifunctional Protein That Also Binds to Fibrinogen. J Biol Chem. 2000;275:13863–71.PubMedCrossRef

13.

Hayes PD, Nasim A, London NJ, et al. In situ replacement of infected aortic grafts with rifampicin-bonded prostheses: the Leicester experience (1992 to 1998). J Vasc Surg. 1999;30:92–8.PubMedCrossRef

14.

Wilson SE. New alternatives in management of the infected vascular prosthesis. Surg Infect (Larchmt). 2001;2:171–5. discussion 175–177.CrossRef

15.

Pitsch R, Lawrence P: Natural history of graft infections. B. TJ. Armonk, NY: Futura; 1994.

16.

Bandyk DF, Berni GA, Thiele BL, Towne JB. Aortofemoral graft infection due to Staphylococcus epidermidis. Arch Surg. 1984;119:102–8.PubMed

17.

Orton DF, LeVeen RF, Saigh JA, et al. Aortic prosthetic graft infections: radiologic manifestations and implications for management. Radiographics. 2000;20:977–93.PubMed

18.

Low RN, Wall SD, Jeffrey RB, et al. Aortoenteric fistula and perigraft infection: evaluation with CT. Radiology. 1990;175:157–62.PubMed

19.

Agarwal R, Brunelli SM, Williams K, et al. Gadolinium-based contrast agents and nephrogenic systemic fibrosis: a systematic review and meta-analysis. Nephrol Dial Transplant. 2009;24:856–63.PubMedCrossRef

20.

Shahidi S, Eskil A, Lundof E, et al. Detection of abdominal Aortic graft infection: comparison of magnetic resonance imaging and indium-labeled white blood cell scanning. Ann Vasc Surg. 2007;21:586–92.PubMedCrossRef

21.

Lauwers P, Van den Broeck S, Carp L, et al. The use of positron emission tomography with (18)F-fluorodeoxyglucose for the diagnosis of vascular graft infection. Angiology. 2008;58:717–24.CrossRef

22.

Keidar Z, Engel A, Hoffman A, et al. Prosthetic vascular graft infection: the role of 18F-FDG PET/CT. J Nucl Med. 2007;48:1230–6.PubMedCrossRef

23.

•• Bruggink JLM, Glaudemans AWJM, Saleem BR, et al. Accuracy of FDG-PET-CT in the diagnostic work-up of vascular prosthetic graft infection. Eur J Vasc Endovasc Surg. 2010;40:348–54. Authors compared results of FDG-PET to CT and combined FDG-PET/CT in 15 patients. FDG-PET was found to have excellent interobserver consistency and provided a better diagnostic accuracy than CT for the diagnosis of PVGIs.PubMedCrossRef

24.

•• Saleem BR, Meerwaldt R, Tielliu IFJ, et al. Conservative treatment of vascular prosthetic graft infection is associated with high mortality. Am J Surg. 2010;200:47–52. Authors report outcomes on 44 patients with PVGIs. Conservative treatment with antibiotics alone was found to be the only variable associated with poor outcome.PubMedCrossRef

25.

Roy D, Grove DI. Efficacy of long-term antibiotic suppressive therapy in proven or suspected infected abdominal aortic grafts. J Infect. 2000;40:184–7.PubMed

26.

Baddour LM, The Infectious Diseases Society of America’s Emerging Infections Network. Long-term suppressive antimicrobial therapy for intravascular device-related infections. Am J Med Sci. 2001;322:209–12.PubMedCrossRef

27.

Younis G, Reul GJ, Krajcer Z. Combined endovascular and surgical treatment of infected carotid-carotid bypass graft. J Endovasc Ther. 2006;13:687–92.PubMedCrossRef

28.

Javerliat I, Goëau-Brissonnière O, Bruneval P, Coggia M. Experimental study of a new vascular graft prebonded with antibiotic: healing, toxicity, and antibiotic retention. Ann Vasc Surg. 2007;21:603–10.PubMedCrossRef

29.

Giacometti A, Cirioni O, Ghiselli R, et al. Polycationic peptides as prophylactic agents against methicillin-susceptible or methicillin-resistant Staphylococcus epidermidis vascular graft infection. Antimicrob Agents Chemother. 2000;44:3306–9.PubMedCrossRef

30.

Huh J, Chen JC, Furman GM, et al. Local treatment of prosthetic vascular graft infection with multivesicular liposome-encapsulated amikacin. J Surg Res. 1998;74:54–8.PubMedCrossRef

31.

Yasim A, Gul M, Atahan E, et al. Efficacy of vancomycin, teicoplanin and fusidic acid as prophylactic agents in prevention of vascular graft infection: an experimental study in rat. Eur J Vasc Endovasc Surg. 2006;31:274–9.PubMedCrossRef

32.

O’Connor S, Andrew P, Batt M, Becquemin JP. A systematic review and meta-analysis of treatments for aortic graft infection. J Vasc Surg. 2006;44:38–45.e38.PubMedCrossRef

33.

Chiesa R, Astore D, Frigerio S, et al. Vascular prosthetic graft infection: epidemiology, bacteriology, pathogenesis and treatment. Acta Chir Belg. 2002;102:238–47.PubMed

34.

• Sato S, Nitta Y, Saiki Y, et al. Enhanced perigraft angiogenesis prevents prosthetic graft infection. Ann Thorac Surg. 2008;86:1278–84. In vitro experiments in this study demonstrated that incorporation of basic fibroblast growth factor into graft material was associated with decreased number of bacterial colonies and enhanced angiogenesis.PubMedCrossRef

35.

•• Sohail MR, Wilson WR, Baddour LM. Infections of nonvalvular cardiovascular devices. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practice of infectious diseases. Philadelphia: Churchill Livingstone/Elsevier; 2010. p. 1127–42. Comprehensive review of various aspects related to PVGIs.

Titel: Prosthetic Vascular Graft Infections: A Contemporary Approach to Diagnosis and Management
verfasst von: Avish Nagpal
Muhammad R. Sohail
Publikationsdatum: 01.08.2011
Verlag: Current Science Inc.
Erschienen in: Current Infectious Disease Reports / Ausgabe 4/2011
Print ISSN: 1523-3847
Elektronische ISSN: 1534-3146
DOI: https://doi.org/10.1007/s11908-011-0191-y

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

Reizdarmsyndrom: Diäten wirksamer als Medikamente

29.04.2024 Reizdarmsyndrom Nachrichten

Bei Reizdarmsyndrom scheinen Diäten, wie etwa die FODMAP-arme oder die kohlenhydratreduzierte Ernährung, effektiver als eine medikamentöse Therapie zu sein. Das hat eine Studie aus Schweden ergeben, die die drei Therapieoptionen im direkten Vergleich analysierte.

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

25.04.2024 Allergien und Intoleranzreaktionen Nachrichten

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2011

Prevention of Central Line–Associated Bloodstream Infections: A Journey Toward Eliminating Preventable Harm

Healthcare-Associated Bacterial Meningitis

Guillain-Barré Syndrome Following Influenza Vaccination: Causal or Coincidental?

Synergy: A Cautionary Tale

The Changing Landscape of Progressive Multifocal Leukoencephalopathy