Erschienen in:
01.10.2016 | Research Letter
Publication of Cost-of-Illness Studies: Does Methodological Complexity Matter?
verfasst von:
T. Joseph Mattingly II, C. Daniel Mullins, Eberechukwu Onukwugha
Erschienen in:
PharmacoEconomics
|
Ausgabe 10/2016
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Excerpt
Cost-of-illness (COI) refers to the economic framework researchers have used to measure and describe the costs associated with specific diseases [
1]. Expansion in the number as well as the types of methods used to calculate COI have been reported over time; however, utilization of more complex methods has remained unchanged [
2‐
4]. With this expansion, inconsistencies observed across cost calculations for the same disease state raise questions about the validity and usefulness of these studies [
5]. A review of 21 COI studies on Alzheimer’s disease found that total annual costs varied from US$5.6 billion to US$88.3 billion in the United States, demonstrating the wide variability [
6]. …