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Journal of Natural Medicines

Erschienen in:

22.03.2018 | Note

Quantification of terpene trilactones in Ginkgo biloba with a ¹H NMR method

verfasst von: Tingfu Liang, Takuya Miyakawa, Jinwei Yang, Tsutomu Ishikawa, Masaru Tanokura

Erschienen in: Journal of Natural Medicines | Ausgabe 3/2018

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Abstract

Ginkgo biloba L. has been used as a herbal medicine in the traditional treatment of insufficient blood flow, memory deficits, and cerebral insufficiency. The terpene trilactone components, the bioactive agents of Ginkgo biloba L., have also been reported to exhibit useful functionality such as anti-inflammatory and neuroprotective effects. Therefore, in the present research, we attempted to analyze quantitatively the terpene trilactone components in Ginkgo biloba leaf extract, with quantitative ¹H NMR (qNMR) and obtained almost identical results to data reported using HPLC. Application of the qNMR method for the analysis of the terpene trilactone contents in commercial Ginkgo extract products, such as soft gel capsules and tablets, produced the same levels noted in package labels. Thus, qNMR is an alternative method for quantification of the terpene trilactone components in commercial Ginkgo extract products.

Flavonoid components are known as an alternative compound group, e.g., kaempferol, quercetin, and isorhamnetin [6].

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Titel: Quantification of terpene trilactones in Ginkgo biloba with a 1H NMR method
verfasst von: Tingfu Liang
Takuya Miyakawa
Jinwei Yang
Tsutomu Ishikawa
Masaru Tanokura
Publikationsdatum: 22.03.2018
Verlag: Springer Singapore
Erschienen in: Journal of Natural Medicines / Ausgabe 3/2018
Print ISSN: 1340-3443
Elektronische ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-018-1203-0

Springer Medizin

Abstract

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