Erschienen in:
01.12.2018 | Spondyloarthritis (M Khan, Section Editor)
Radiographic Progression in Ankylosing Spondylitis: From Prognostication to Disease Modification
verfasst von:
Ismail Sari, Nigil Haroon
Erschienen in:
Current Rheumatology Reports
|
Ausgabe 12/2018
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Abstract
Purpose of Review
Pain, functional limitation, and spinal damage are the three main domains that have significant impact on various aspects of axial spondyloarthritis (axSpA).
Recent Findings
Several randomized controlled trials (RCTs) showed a beneficial effect of non-steroid ant-inflammatory drugs (NSAIDs) and biologic treatments on pain and function. The effect of available treatments on spinal damage is still of interest and is being studied.
Summary
In this article, we review the literature on radiographic progression in axSpA. We discuss the natural course of spinal progression, predictors of spinal damage, and the effect of lifestyle changes and medications on radiographic progression in axSpA.