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Die Highlights vom Kongress des American College of Cardiology 2024

Im April diskutierten die Herz-Kreislauf-Spezialisten aus der ganzen Welt auf dem  Kongress des American College of Cardiology (ACC) u.a. neue Therapieansätze bei akutem Myokardinfarkt, koronarer Herzerkrankung, kardiogenem Schock oder Aortenklappenstenose. In unserem Kongress-Dossier haben wir für Sie Berichte über die „Late-Breaking Trials“ und andere wichtige Studien zusammengestellt. 
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Arthritis Research & Therapy
Erschienen in: Arthritis Research & Therapy 1/2009

01.02.2009 | Review

Randomized controlled trial design in rheumatoid arthritis: the past decade

verfasst von: Vibeke Strand, Jeremy Sokolove

Erschienen in: Arthritis Research & Therapy | Ausgabe 1/2009

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Abstract

Much progress has occurred over the past decade in rheumatoid arthritis trial design. Recognized challenges have led to the establishment of a clear regulatory pathway to demonstrate efficacy of a new therapeutic. The use of pure placebo beyond 12 to 16 weeks has been demonstrated to be unethical and thus background therapy and/or early rescue has become regular practice. Goals of remission and 'treating to targets' may prove more relevant to identify real-world use of new and existing therapeutics. Identification of rare adverse events associated with new therapies has resulted in intensive safety evaluation during randomized controlled trials and emphasis on postmarketing surveillance and use of registries.
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Metadaten
Titel
Randomized controlled trial design in rheumatoid arthritis: the past decade
verfasst von
Vibeke Strand
Jeremy Sokolove
Publikationsdatum
01.02.2009
Verlag
BioMed Central
Erschienen in
Arthritis Research & Therapy / Ausgabe 1/2009
Elektronische ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar2555

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