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27.05.2019 | Original Paper

Reduced vascular perfusion density in idiopathic epiretinal membrane compared to macular pseudohole

verfasst von: Luisa Pierro, Lorenzo Iuliano, Alessandro Marchese, Alessandro Arrigo, Alessandro Rabiolo, Francesco Bandello

Erschienen in: International Ophthalmology | Ausgabe 12/2019

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Abstract

Purpose

To investigate the retinal capillary perfusion density by means of optical coherence tomography angiography (OCT-A) in idiopathic epiretinal membrane (ERM) and macular pseudoholes (MPH).

Methods

This observational cross-sectional study examined consecutive patients affected by ERM and MPH presenting between June 2017 and December 2017, as well as the 30 eyes of 30 healthy subjects. All patients underwent swept-source OCT-A examination. For each patient, vessel perfusion density and foveal avascular zone (FAZ) area were measured.

Results

Twenty-five eyes of 20 patients with ERM and 28 eyes of 24 patients with MPH were enrolled. Thirty eyes of 30 age-matched healthy controls were included. The perfusion density in the superficial capillary plexus (SCP) of ERM (0.401 ± 0.012) turned out to be inferior that MPH (0.419 ± 0.018) and controls (0.415 ± 0.017) (p < 0.01), while no significant differences were evident among the three subgroups in the deep capillary plexus (DCP) (p = 0.1). The FAZ area in the SCP was smaller in the ERM group (0.168 ± 0.123 mm²), respectively, than MPH (0.295 ± 0.013 mm²) and controls (0.213 ± 0.107 mm²) (p < 0.01), otherwise no difference were noted in the DCP (p = 0.14).

Conclusions

OCT-A morphological features differ between idiopathic ERM and MPH, showing lower perfusion density in idiopathic ERM compared to MPH.

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Titel: Reduced vascular perfusion density in idiopathic epiretinal membrane compared to macular pseudohole
verfasst von: Luisa Pierro
Lorenzo Iuliano
Alessandro Marchese
Alessandro Arrigo
Alessandro Rabiolo
Francesco Bandello
Publikationsdatum: 27.05.2019
Verlag: Springer Netherlands
Erschienen in: International Ophthalmology / Ausgabe 12/2019
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-019-01119-3

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Reduced vascular perfusion density in idiopathic epiretinal membrane compared to macular pseudohole

Abstract

Purpose

Methods

Results

Conclusions

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Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

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