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Journal of Bone and Mineral Metabolism

Erschienen in:

03.03.2022 | Original Article

Relationship between oseteoporosis with fatty infiltration of paraspinal muscles based on QCT examination

verfasst von: Xiangwen Li, Yuxue Xie, Rong Lu, Yuyang Zhang, Hongyue Tao, Shuang Chen

Erschienen in: Journal of Bone and Mineral Metabolism | Ausgabe 3/2022

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Abstract

Introduction

To investigate the correlation between paraspinal muscles features and osteoporosis in lumbar spine.

Materials and methods

A total of 367 subjects who underwent quantitative computed tomography (QCT) examination were enrolled in this study. QCT pro workstation was used to obtain the mean bone mineral density (BMD) of the lower lumbar spine. Fat fraction (FF) and cross-section area (CSA) of the paraspinal muscles at the corresponding levels were measured. All participants were divided into normal, osteopenia, and osteoporosis groups. One-way ANOVA and independent samples t tests were performed to compare differences between groups. Pearson and Spearman correlation coefficients and partial correlation analysis after controlling for confounding factors were used to analyze the correlation between BMD and paraspinal muscles measurements.

Results

Among the 367 participants included, 116 were in the normal group, 130 in the osteopenia group and 121 in the osteoporosis group. There were significant differences among the three groups for the mean and multifidus FF. BMD showed negative correlations with the FF of the paraspinal muscles. Multifidus and mean FF showed the best correlation (r = − 0.654, − 0.777). There were also significant differences in the mean and multifidus FF between different age groups, while after controlling for confounding factors, there was no correlation between age and FF of the paraspinal muscles.

Conclusion

This preliminary study demonstrated the association of BMD with fatty infiltration of paraspinal muscles. Different muscles might have specific effects in different sex and age groups.

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Titel: Relationship between oseteoporosis with fatty infiltration of paraspinal muscles based on QCT examination
verfasst von: Xiangwen Li
Yuxue Xie
Rong Lu
Yuyang Zhang
Hongyue Tao
Shuang Chen
Publikationsdatum: 03.03.2022
Verlag: Springer Nature Singapore
Erschienen in: Journal of Bone and Mineral Metabolism / Ausgabe 3/2022
Print ISSN: 0914-8779
Elektronische ISSN: 1435-5604
DOI: https://doi.org/10.1007/s00774-022-01311-z

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Relationship between oseteoporosis with fatty infiltration of paraspinal muscles based on QCT examination

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Introduction

Materials and methods

Results

Conclusion

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