Erschienen in:
29.04.2020 | Letter to the Editor
Reply to the letter
verfasst von:
Hirohisa Okabe, Yo-ichi Yamashita, Hatem A. Elmezayen, Hiromitsu Hayashi, Katsunori Imai, Hideo Baba
Erschienen in:
Surgery Today
|
Ausgabe 10/2020
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Excerpt
Grizzi et al. suggested the importance of a scientific method to quantitatively or semi-quantitatively evaluate liver fibrosis, which was missing in our latest report, ‘Clinical role of serum programmed death ligand 1 in patients with hepatocellular carcinoma: Where does it come from?’ [
1] In this report, we investigated the role of serum programmed death ligand 1 (PD-L1) level by analyzing both the serum PD-L1 level and the tissue PD-L1 expression status in the tumor and the corresponding background liver by an immunological approach. Grizzi et al. indicated that the New Inuyama Classification [
2] was based on the grade of fibrosis, which should be quantitatively discriminated. They recommend their original methodology, which would enable us to quantitatively or semi-quantitatively determine the extent of liver fibrosis [
3]. …
